Results 51 to 60 of about 43,164 (298)

Sampling algorithms for validation of supervised learning models for Ising-like systems

open access: yes, 2016
In this paper, we build and explore supervised learning models of ferromagnetic system behavior, using Monte-Carlo sampling of the spin configuration space generated by the 2D Ising model.
Portman, Nataliya, Tamblyn, Isaac
core   +1 more source

Rapid flipping of parametric phase states

open access: yes, 2019
Since the invention of the solid-state transistor, the overwhelming majority of computers followed the von Neumann architecture that strictly separates logic operations and memory.
Akin, Abdulkadir   +10 more
core   +1 more source

QUBO Simplification by Singular Value Decomposition and Coefficient Elimination for Ising Machines

open access: yesIEEE Access
Ising machines, including quantum annealing machines, can efficiently solve combinatorial optimization problems by formulating them as Quadratic Unconstrained Binary Optimization (QUBO). However, it is known that the solving performance of Ising machines
Shinnosuke Inaba   +2 more
doaj   +1 more source

Scale-invariant Feature Extraction of Neural Network and Renormalization Group Flow

open access: yes, 2018
Theoretical understanding of how deep neural network (DNN) extracts features from input images is still unclear, but it is widely believed that the extraction is performed hierarchically through a process of coarse-graining.
Iso, Satoshi   +2 more
core   +1 more source

Geometric Theory of Ising Machines

open access: yesCoRR
We contribute to the mathematical theory of the design of low temperature Ising machines, a type of experimental probabilistic computing device implementing the Ising model. Encoding the output of a function in the ground state of a physical system allows efficient and distributed computation, but the design of the energy function is a difficult puzzle.
Andrew G. Moore   +2 more
openaire   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

AAA+ protein unfoldases—the Moirai of the proteome

open access: yesFEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

A GPU-Based Ising Machine With a Multi-Spin-Flip Capability for Constrained Combinatorial Optimization

open access: yesIEEE Access
Ising machines are domain-specific computers that solve combinatorial optimization problems (COPs). They utilize an Ising model to represent a COP and search for the optimal spin configuration of the Ising model to solve the COP.
Satoru Jimbo   +4 more
doaj   +1 more source

A note on analyzing the stability of oscillator Ising machines

open access: yesElectronics Letters, 2023
Abstract The rich non‐linear dynamics of the coupled oscillators (under second harmonic injection) can be leveraged to solve computationally hard problems in combinatorial optimization such as finding the ground state of the Ising Hamiltonian. While prior work on the stability of the so‐called Oscillator Ising Machines (OIMs) has used
Mohammad Khairul Bashar   +2 more
openaire   +3 more sources

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett   +8 more
wiley   +1 more source

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