Results 271 to 280 of about 20,721,849 (338)

A modified Ising model of Barabási-Albert network with gene-type spins. [PDF]

open access: yesJ Math Biol, 2020
Krishnan J   +3 more
europepmc   +1 more source

Critical Role of IL1R2‐ENO1 Interaction in Inhibiting Glycolysis‐Mediated Pyroptosis for Protection Against Lethal Sepsis

open access: yesAdvanced Science, EarlyView.
The authors have discovered that intracellular interleukin 1 receptor 2 (IL1R2) negatively regulates pyroptosis and inflammation by inhibiting glycolysis in sepsis. Soluble IL1R2 is released from macrophages undergoing pyroptosis. IL1R2 acts as a novel negative regulator of glycolysis by interacting with enolase 1 (ENO1), thereby inhibiting gasdermin D
Chuyi Tan   +13 more
wiley   +1 more source

Bionic Nanostructures Create Mechanical Signals to Mediate the Composite Structural Bone Regeneration Through Multi‐System Regulation

open access: yesAdvanced Science, EarlyView.
Inspired by the structural and functional characteristics of bone, bionic nanomaterials combined with nanotechnology can more accurately replicate stem cell niches, enabling the design of bone tissue engineering scaffolds with diverse nanoscale properties to promote stem cell migration, proliferation, and differentiation. This precise control over stem
Yangfan Pei   +11 more
wiley   +1 more source

Regenerative Hair Pigmentation via Skin Organoids: Adaptive Patterning Mediated by Collagen VI and Semaphorin 3C

open access: yesAdvanced Science, EarlyView.
The release of COL6A3 by fibroblasts is sensed by the CD44 receptor on melanocytes, activating glutathione (GSH) metabolism and increasing melanocyte survival during skin organoid culture. SEMA3C released by bulge cells binds to the NRP1 receptor on melanocytes, regulating microtubule stability and promoting melanocyte recruitment and function during ...
Tingting Li   +17 more
wiley   +1 more source

Quantitative Electron Beam‐Single Atom Interactions Enabled by Sub‐20‐pm Precision Targeting

open access: yesAdvanced Science, EarlyView.
Atomic lock‐on (ALO) is a rapid, low‐dose in situ technique in scanning transmission electron microscopy (STEM) that achieves sub‐20 picometer (pm) beam positioning. A sparse annular scan collects positional information while avoiding irradiation of the target site.
Kevin M. Roccapriore   +2 more
wiley   +1 more source

Imprinting Electrically Switchable Scalar Spin Chirality by Anisotropic Strain in a Kagome Antiferromagnet

open access: yesAdvanced Science, EarlyView.
It is shown that anisotropic strain offers a novel approach to control the magnetic ground state in heterostructures of a Kagome antiferromagnet, unlocking new functionalities. This strain induces finite scalar spin chirality, resulting in a pronounced Berry curvature in momentum space, leading to room‐temperature anomalous Hall effect.
Debjoty Paul   +11 more
wiley   +1 more source

The Affective Ising Model: A computational account of human affect dynamics. [PDF]

open access: yesPLoS Comput Biol, 2020
Loossens T   +5 more
europepmc   +1 more source

Drug Resistance Predictions Based on a Directed Flag Transformer

open access: yesAdvanced Science, EarlyView.
 CAPTURE, a deep learning framework combining structural and sequence data to predict drug‐resistant Mpro mutations, revealing that PAXLOVID use may be accelerating resistance—supporting real‐time viral surveillance and therapeutic design. Abstract The evolving SARS‐CoV‐2 virus threatens global public health, particularly with potential resistance to ...
Dong Chen   +8 more
wiley   +1 more source

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