Results 291 to 300 of about 20,721,849 (338)

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source

Critical Electrochemistry Technologies Applicable in Space Exploration

Advanced Science, EarlyView.
The available resources in space and discuss the application scenarios and challenges of electrochemical methods in four critical domains is analyzed: metallurgical processing of mineral resources, water resources utilization, carbon cycle management in extraterrestrial habitats, and electrical energy storage.
Ruisi Xu, Zepeng Lv, Shaolong Li, Jilin He, Jianxun Song   +4 more
wiley   +1 more source

A New Quasi‐Solid Polymer Electrolyte for Next‐Generation Na–O2 Batteries: Unveiling the Potential of a Polyamide‐Polyether System

Advanced Science, EarlyView.
This study introduces a novel, sustainable Pebax1657‐based quasi‐solid polymer electrolyte (QSPE) that enhances the performance and safety of sodium–oxygen (Na–O2) batteries. The developed QSPE shows improved Na+ ion transport, reduced overpotentials, and better cycling stability compared to the conventional liquid systems, highlighting its potential ...
Mohamed Yahia, Marina Enterría, Cristina Pozo‐Gonzalo, Nagore Ortiz‐Vitoriano   +3 more
wiley   +1 more source

Hypercontractivity and spectral gap of symmetric diffusions with applications to the stochastic Ising models

, 1990
Jean‐Dominique Deuschel, Daniel W. Stroock   +1 more
openalex   +1 more source

An in‐depth Study of the Solid Electrolyte Interphase Compositional Evolution in Sodium‐Ion Batteries: Unravelling the Effects of a Na Metal Counter Electrode on the SEI

Advanced Science, EarlyView.
Compositional evolution of the solid electrolyte interphase in Na‐ion batteries is investigated, focusing on the effects of sodium metal counter electrodes on interphase formation. Advanced analytical techniques are employed to uncover distinct differences in interphase chemistry in half‐cell versus full‐cell configurations.
Jack R. Fitzpatrick, Beth E. Murdock, Pardeep K. Thakur, Tien‐Lin Lee, Sarah Fearn, Andrew J. Naylor, Deepnarayan Biswas, Nuria Tapia‐Ruiz   +7 more
wiley   +1 more source

The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis

Advanced Science, EarlyView.
This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen, Chuan Wu, Fei Tang, Jingyue Zhou, Li Mo, Yanping Li, Jinhan He   +6 more
wiley   +1 more source

β‐Mangostin Attenuates TET2‐Mediated DNA Demethylation of Prkcg in the Prevention of Intervertebral Disc Degeneration

Advanced Science, EarlyView.
β‐Mangostin alleviates intervertebral disc degeneration through dual modulation of macrophage polarization and the TET2‐Prkcg axis in nucleus pulposus cells. Abstract Intervertebral disc degeneration (IDD) induced lower back pain is a main cause of disability, resulting in a substantial workforce loss worldwide and placing a substantial burden on the ...
Xiangzhen Kong, Hanwen Gu, Yuanqiang Zhang, Qunbo Meng, Qi Li, Kangle Song, Yanlin Li, Kaiwen Liu, Zhenchuan Liu, Rui Hu, Haoxi Zhai, Tian Li, Zemin Ling, Zhijian Wei, Fuxin Wei, Lei Cheng   +15 more
wiley   +1 more source

The Phenomenology of Strings and Clusters in the 3-d Ising Model

, 1994
Vladimir Dotsenko, Geoff Harris, Enzo Marinari, Emil J. Martinec, Marco Picco, Paul Windey   +5 more
openalex   +2 more sources

Ultra‐Low Hysteresis Under Large Deformation Enabled by Fast Chains Relaxation in Highly Competitive Dynamic Hydrogen Bond Networks

Advanced Science, EarlyView.
This study demonstrates that incorporating deep eutectic solvent (DES) components tunes the relaxation dynamics of strong hydrogen bonds between polymer segments, rendering them mechanically “invisible” during service conditions (low hysteresis: <3%).
Shuaijun Guo, Shilei Zhu, Yang Qiao, Shanhao Feng, Xin Yang, Beibei Kang, Chaojun Yue, Yanjing Zhang, Zhuangzhuang Li, Ya Nan Ye, Qiang Zheng   +10 more
wiley   +1 more source

Reconstruction of the finite size canonical ensemble from incomplete micro-canonical data

Open Physics, 2009
Lundow Per, Markström Klas
doaj   +1 more source