Results 21 to 30 of about 12,049 (227)

Dynamic association of antimicrobial resistance in urinary isolates of Escherichia coli and Klebsiella pneumoniae between primary care and hospital settings in the Netherlands (2008–2020): a population-based studyResearch in context

The Lancet Regional Health. Europe
Summary: Background: It is unclear whether changes in antimicrobial resistance (AMR) in primary care influence AMR in hospital settings. Therefore, we investigated the dynamic association of AMR between primary care and hospitals.
Evelyn Pamela Martínez, Annelies Verbon, Annelot F. Schoffelen, Wieke Altorf-van der Kuil, Joost van Rosmalen, James W.T. Cohen Stuart, Damian C. Melles, Karin van Dijk, Ali Alzubaidy, Maarten Scholing, Sacha D. Kuil, Gert J. Blaauw, Wieke Altorf - van der Kuil, Saskia M. Bierman, Sabine C. de Greeff, Sonja R. Groenendijk, Rudy Hertroys, Jos C.M. Monen, Daan W. Notermans, Jan Polman, Wouter J. van den Reek, Caroline Schneeberger-van der Linden, Annelot F. Schoffelen, Feline Velthuis, Cornelia C.H. Wielders, Britt J. de Wit, Rony E. Zoetigheid, Wouter van den Bijllaardt, Elise M. Kraan, Michiel B. Haeseker, Júlia M. da Silva, Eefje de Jong, Boulos Maraha, Arjanne J. van Griethuysen, Bastiaan B. Wintermans, Marijke J.C.A. van Trijp, Anouk E. Muller, Man-Chi Wong, Alewijn Ott, Erik Bathoorn, Mariëtte Lokate, Jan Sinnige, Damian C. Melles, Nienke Plantinga, Nicole H.M. Renders, Julia W. Dorigo-Zetsma, Leendert J. Bakker, Wim Ang, Karola Waar, Martha T. van der Beek, Maurine A. Leversteijn-van Hall, Suzan P. van Mens, Erik Schaftenaar, Marrigje H. Nabuurs-Franssen, Ianthe Maat, Patrick D.J. Sturm, Bram M.W. Diederen, Lonneke G.M. Bode, David S.Y. Ong, Michiel van Rijn, Sander Dinant, Martijn den Reijer, Dick W. van Dam, Els I.G.B. de Brauwer, Robbert G. Bentvelsen, Anton G.M. Buiting, Anne L.M. Vlek, Melanie de Graaf, Annet Troelstra, Arjan R. Jansz, Maurits P.A. van Meer, Janneke de Vries, Julian D. Machiels   +72 more
doaj   +1 more source

Effect of Nitrosative Stress on the S-Nitroso-Proteome of Paracoccidioides brasiliensis

Frontiers in Microbiology, 2020
The fungi Paracoccidioides brasiliensis and Paracoccidioides lutzii are the causative agents of paracoccidioidomycosis (PCM), a systemic mycosis endemic to Latin America.
Marina V. Navarro, Alison F. A. Chaves, Daniele G. Castilho, Isis Casula, Juliana C. P. Calado, Palloma M. Conceição, Leo K. Iwai, Beatriz F. de Castro, Wagner L. Batista, Wagner L. Batista   +9 more
doaj   +1 more source

On‐Surface Indigo‐Based Bimolecular Coordination Networks with Programmable Regular or Vitreous Structure

Advanced Functional Materials, EarlyView.
A previously unreported coordination motif stabilising single Fe atoms by indigo chelation and pyridyl coordination on Au(111) has been revealed. By using planar tritopic pyridyl linkers (TPyB), extended 2D porous networks of indigo3(TPyB)2Fe6 form. These networks can be crystalline or vitreous and offer an environment where individual coordination ...
Hongxiang Xu, Ritam Chakraborty, Biao Yang, Dennis Meier, Joachim Reichert, Svetlana Klyatskaya, Mario Ruben, Shobhana Narasimhan, Johannes V. Barth, Anthoula C. Papageorgiou   +9 more
wiley   +1 more source

Third-generation cephalosporin resistant gram-negative bacteraemia in patients with haematological malignancy; an 11-year multi-centre retrospective study

Annals of Clinical Microbiology and Antimicrobials, 2022
Objectives Among patients with haematological malignancy, bacteraemia is a common complication during chemotherapy-induced neutropenia. Resistance of gram-negative bacteria (GNB) to third-generation cephalosporins (3GC) is increasing. In order to explore
Jara R. de la Court, Sjoukje H. S. Woudt, Annelot F. Schoffelen, Jarom Heijmans, Nick A. de Jonge, Tjomme van der Bruggen, Marije K. Bomers, Merel M. C. Lambregts, Rogier P. Schade, Kim C. E. Sigaloff, ISIS-AR study group   +10 more
doaj   +1 more source

Unlocking the Potential of MXene‐Based Electrochemical Biosensors: A Review of Biofunctionalization Strategies and Biosensing Principles

Advanced Materials Technologies, EarlyView.
ABSTRACT Electrochemical biosensors enable the accurate and timely detection of clinical biomarkers, improving healthcare and precision medicine. MXene nanosheets, a class of 2D transition metal carbides, nitrides, and carbonitrides, are promising materials for developing next‐generation electrochemical biosensors due to their unique physicochemical ...
Muhsin Ali, Sharat Chandra Barman, Isobel Steer, Aya H. Alshareef, Dana Alsulaiman   +4 more
wiley   +1 more source

Predicting Macrophage Spatial Localization from Single‐Cell Transcriptomes to Uncover Disease Mechanisms

Advanced Science, EarlyView.
This study presents a machine‐learning framework entitled MERLIN that infers the microanatomical localization of macrophages from single‐cell transcriptomic data in structured organs such as the kidney and brain. Applying this method to existing datasets from models of acute kidney injury and diabetic nephropathy uncovered spatially resolved insights ...
Junping Yin, Qi Mei, Hans‐Joachim Paust, Ning Song, Yu Zhao, Daniela Klaus, Melanie Eichler, Yijun Hua, Jie Qin, Weiting Cheng, Christina K. Weisheit, Veronika Lukacs‐Kornek, Isis Ludwig‐Portugall, Sibylle von Vietinghoff, Christian F. Krebs, Johanna Klughammer, Ulf Panzer, Christian Kurts, Jian Li   +18 more
wiley   +1 more source

Establishment of primary mixed cell cultures from spontaneous canine mammary tumors: Characterization of classic and new cancer-associated molecules. [PDF]

PLoS ONE, 2017
There are many factors which make canine cancer like cancer in humans. The occurrence of spontaneous mammary tumors in pet dogs, tumor genetics, molecular targets and exposure to the same environmental risk factors are among these factors. Therefore, the
Luciana B Gentile, Marcia K Nagamine, Luiz R Biondi, Daniel S Sanches, Fábio Toyota, Tatiane M Giovani, Isis P de Jesus, Ivone I M da Fonseca, Nicolle Queiroz-Hazarbassanov, Bruno L Diaz, Cristina de O Massoco Salles Gomes, Maria Lucia Z Dagli   +11 more
doaj   +1 more source

Unraveling the Morphological and Functional Maturation Mechanisms Underlying Human Neural Development Using iPSCs‐Derived Neuronal Model

Advanced Science, EarlyView.
Using human induced pluripotent stem cells (hiPSCs)‐derived neuronal model, Tian and colleagues reveal that voltage‐gated calcium channels Cav1.2 and Cav1.3, and their mediated calcium ion influx, are essential for early morphogenesis of human neuronal development, while ECEL1 underlies human neuronal functional developmental maturation through CALM3 ...
Yue Tian, Yi‐Chun Ou, Zi‐Xian Zhang, Jie Cai, Si‐Qing Cai, Guo‐Gang Xing   +5 more
wiley   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

XOR‐Logic Phase Coding Programmable Metasurface for Low Power‐Consumption Systems

Advanced Science, EarlyView.
By leveraging XOR logic, the biasing‐network complexity of 2D programmable metasurfaces is reduced from m×n to m+n through efficient row‐column control. This enables versatile functions including beam deflection and beamforming, facilitating applications in wireless communications and beyond.
Ruichao Zhu, Sai Sui, Junyan Dai, Qunyan Zhou, Yuxiang Jia, Yajuan Han, Yuxi Li, Shaojie Wang, Qiang Cheng, Jiafu Wang, Tie Jun Cui   +10 more
wiley   +1 more source