Results 111 to 120 of about 25,969 (255)

Systematic Review of the Huntington's Disease Drug Development Pipeline, 2014 to 2025

Movement Disorders, EarlyView.
Abstract Background In the past decade, significant advances have improved our understanding of the mechanisms underlying HD pathobiology leading to several putative therapeutic targets for HD. Objective The aim was to describe the Huntington's disease (HD) drug development clinical pipeline.
Pavlina Konstantinova, Jenny Townhill, Juliana Bronzova, Viktoria Andreeva, Swati Sathe, Cristina Sampaio   +5 more
wiley   +1 more source

Analyzing ISIS\'s Impact on Middle East\'s Political-Security Equationsations

تحقيقات جغرافيايی, 2018
This article seeks to examine the effects of the rise of ISIS (Islamic State in Iraq and Syria) in Syria and Iraq on the political-security equations and power developments in the West Asia region.
Hamzeh Safavi, Ali Mohamad Khaksar
doaj  

Melanopsin‐Mediated Post‐Illumination Pupillary Response in Idiopathic Rapid Eye Movement (REM) Sleep Behavior Disorder and Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Aims To conduct a case–control study to investigate melanopsin‐mediated post‐illumination pupillary response (PIPR) in patients with Parkinson's disease (PD), video‐polysomnography‐confirmed isolated/idiopathic rapid eye movement (REM) sleep behavior disorder (iRBD), and age‐matched healthy controls (HC). Methods PIPR was measured at 6 s after
Joey W.Y. Chan, Bei Huang, Siyi Gong, Yuhua Yang, Shi Tang, Steven Wai‐ho Chau, Ngan Yin Chan, Tim Man‐ho Li, Yaping Liu, Anne Y.Y. Chan, Karen K.Y. Ma, Shirley X. Li, Joshua Tsoh, Kelvin K.L. Chong, Kathryn A. Roecklein, Vincent C.T. Mok, Yun Kwok Wing   +16 more
wiley   +1 more source

From Biological Fractal Dynamics to Analog Fractional‐Order Circuits: A System Design Framework Based on Operatorization Thought

International Journal of Mechanical System Dynamics, EarlyView.
ABSTRACT Fractional calculus, with its unique advantage in describing memory and nonlocal effects, has become a key tool for modeling nonlinear dynamic systems. Its integration with circuit systems has opened up a new paradigm for modern circuit design.
Zhimo Jian, Zheng Li, Gang Peng, Chaoqian Luo, Yajun Yin   +4 more
wiley   +1 more source

Fatigue in Myasthenia Gravis: Recent Advances and Emerging Concepts

Muscle &Nerve, EarlyView.
ABSTRACT Fatigue is a common, often disabling symptom in myasthenia gravis (MG), distinct from muscle fatigability, and strongly associated with reduced quality of life. This narrative review examines current evidence on fatigue in MG, its patient impact, and future research directions. Earlier studies, mostly small and heterogeneous, reported a highly
Yvonne J. M. Campman, Martijn R. Tannemaat, Annabel M. Ruiter, Sarah Hoffmann   +3 more
wiley   +1 more source

Does bigger mean sicker? A systematic review and meta‐analysis of the intraspecific relationship between host body size and parasite infection across vertebrate taxa

Oikos, EarlyView.
Elucidating the determinants of parasite infection levels of individuals within a population is a basic but important step for understanding the roles of parasites in natural systems. Among intraspecific studies on vertebrate hosts and metazoan parasites, host body size (length/mass) is probably the most frequently reported factor determining parasite ...
Ryota Hasegawa, Daniela de Angeli Dutra, Bronwen Presswell, Jerusha Bennett, Cameron McDougall, Katherine E. Buschang, Xuhong Chai, Robert Poulin   +7 more
wiley   +1 more source

A presumptive diagnosis of feline hyperesthesia syndrome due to stressful human-related condition: case report. [PDF]

Vet Res Commun
Silveira de Moraes R, da Silva Vieira Ribeiro M, Corrêa LL, Purcena da Guimarães Silveira H, Dos Reis Paludo RL, Moreira CN, de Souza Ramos DG, Braga ÍA.   +7 more
europepmc   +1 more source

Islamic Public Administration in Practice: The Taliban's “Gender Apartheid” Governance in Afghanistan

Public Administration and Development, EarlyView.
ABSTRACT This article analyzes the Taliban's post‐2021 governance model through the Islamic Public Administration (IPA) framework, focusing on justice, equality, and women's inclusion. It asks: (1) How does the Taliban's governance align with core IPA principles?
Parwiz Mosamim, Jean‐Patrick Villeneuve   +1 more
wiley   +1 more source

Sleep Disturbances Among Yazidi Survivors of the ISIS Genocide: Epidemiology, Neuropsychology, and Culturally Sensitive Interventions. [PDF]

Brain Behav
Kizilhan JI, Ag Z, Ahmed QA, Avidan AY.
europepmc   +1 more source

Hunting motivations, behaviour and forest access: Characterising wildlife hunting practices in a multi‐ethnic, forested landscape of Brunei Darussalam, Southeast Asia

People and Nature, EarlyView.
Abstract Unsustainable hunting practices can alter population dynamics, driving biodiversity declines, which leads to ‘empty forests’. Understanding hunting behaviour, including motivations for hunting and relationships with market drivers, and access to hunting grounds are important to develop affirmative policies to stem biodiversity loss.
Natasha L. M. Mannion, Rachel Gaulton, Maria Erica Jamil, Marion Pfeifer, Johan Willem Ferry Slik, Stephen G. Willis, F. Merlin Franco   +6 more
wiley   +1 more source