Results 21 to 30 of about 108,561 (277)

Geometry Optimization of the ISIS Muon Target [PDF]

open access: yes, 2010
ISIS is the world’s most successful pulsed spallation neutron source that provides beams of neutrons and muons that enable scientists to study the properties of the matter at the atomic level.
Bungau, Adriana   +4 more
core   +3 more sources

Antisense oligonucleotide reduction of apoB-ameliorated atherosclerosis in LDL receptor-deficient mice[S]

open access: yesJournal of Lipid Research, 2011
Chronic elevations of plasma apolipoprotein B (apoB) are strongly associated with cardiovascular disease. We have previously demonstrated that inhibition of hepatic apoB mRNA using antisense oligonucleotides (ASO) results in reductions of apoB, VLDL, and
Adam E. Mullick   +7 more
doaj   +1 more source

Muons at ISIS [PDF]

open access: yesPhilosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences, 2018
For the last 30 years, muon experiments at ISIS pulsed neutron and muon facility at the Rutherford Appleton Laboratory, Oxfordshire have been making a significant contribution to a number of scientific fields. The muon facilities at ISIS consist of eight experimental areas.
A. D. Hillier   +3 more
openaire   +2 more sources

GEANT4 Simulations of the ISIS Muon Target at Rutherford Appleton Laboratory [PDF]

open access: yes, 2009
MuSR science requires the availabilty of intense beams of polarised positive muons. At the ISIS pulsed muon facility at Rutherford Appleton Laboratory the muons are generated from a low Z thin slab graphite target inserted in the proton beam.
Bungau, Adriana, Lord, James
core   +3 more sources

Supramolecular engineering of charge transfer in wide bandgap organic semiconductors with enhanced visible-to-NIR photoresponse

open access: yesNature Communications, 2021
Despite advances in designed supramolecular organic nanowires for optoelectronics, realizing near infrared phototransistors with wide bandgap materials remains a challenge.
Yifan Yao   +9 more
doaj   +1 more source

A Group of Gems with Isis-Tyche Depictions from Ankara

open access: yesAnadolu Araştırmaları, 2022
This study evaluates 13 intaglio engraved ring stones from Ankara through their iconographic features. These artifacts come from the collections of the Ankara Museum of Anatolian Civilizations and the Erimtan Archaeology and Art Museum.
Melih Arslan, Yavuz Yeğin
doaj   +1 more source

CD40 Generation 2.5 Antisense Oligonucleotide Treatment Attenuates Doxorubicin-induced Nephropathy and Kidney Inflammation

open access: yesMolecular Therapy: Nucleic Acids, 2015
Preclinical and clinical data suggest CD40 activation contributes to renal inflammation and injury. We sought to test whether upregulation of CD40 in the kidney is a causative factor of renal pathology and if reduction of renal CD40 expression, using ...
Aaron J Donner   +5 more
doaj   +1 more source

Disposition and Pharmacology of a GalNAc3-conjugated ASO Targeting Human Lipoprotein (a) in Mice

open access: yesMolecular Therapy: Nucleic Acids, 2016
Triantennary N-acetyl galactosamine (GalNAc3)-conjugated antisense oligonucleotides (ASOs) have greatly improved potency via receptor-mediated uptake. In the present study, the in vivo pharmacology of a 2′-O-(2-methoxyethyl)-modified ASO conjugated with ...
Rosie Z Yu   +13 more
doaj   +1 more source

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