Results 171 to 180 of about 366,501 (263)

Rewiring NADH Metabolism Through NQO1‐Mediated Redox Cycling for Targeted Follicular Lymphoma Therapy

Advanced Science, EarlyView.
ABSTRACT Follicular lymphoma (FL) remains an incurable B‐cell malignancy with high relapse rates, and conventional therapies are often limited by significant toxicity, highlighting the need for novel treatments. We identified that FL exhibits markedly low expression of NAD(P)H: quinone oxidoreductase 1 (NQO1), a key enzyme required for activating ...
Jinxing Zhang, Ziqi Wang, Ye Weng, Yulin Fu, Yuelong Jiang, Beilin Zhuang, Wenzi Zeng, Xiangchun Zhang, Bing Xu, Jie Zha, Hongjun Zhuang   +10 more
wiley   +1 more source

A New Contribution on the Sea Slug (Gastropoda: Heterobranchia) Fauna of the Ustica Island Marine Protected Area (Lower Tyrrhenian Sea, Mediterranean). [PDF]

Biology (Basel)
Lombardo A, Marletta G, Chemello R, Ballesteros M.   +3 more
europepmc   +1 more source

A Bone Marrow–Mimetic Hydrogel Enables Dual‐Phase Hemostasis and Vascularized Osteogenesis for Cranial Defects

Advanced Science, EarlyView.
A biomimetic, fiber‐reinforced hydrogel (FE‐PDA@Fib/Gel‐TG) that enables dual‐phase cranial defect repair. The system provides: instant hemostasis in the early stage, and sustained co‐delivery of pro‐angiogenic and osteogenic signals for synergistic vascularized bone regeneration.
Lingbin Che, Donghong Li, Huan Zhang, Tingting Xu, Juhan Li, Xuanzhou Chen, Louis D. Zhang, Shuguang Wang, Dianwen Song, Dongyong Sha   +9 more
wiley   +1 more source

Intensive grazing by green turtles depletes seagrass meadows and constrains turtle growth in Kume Island, Japan. [PDF]

Sci Rep
Okuyama J, Nishizawa H, Sudo K, Shimabukuro H, Yoshida N, Tsukakoshi Y, Murai H, Sasano S, Tamaki M.   +8 more
europepmc   +1 more source

ZDHHC18‐Mediated Palmitoylation of ORF3a Promotes SARS‐CoV‐2 Pathogenesis by Antagonizing TRIM16‐Mediated Ubiquitination and Proteasomal Degradation

Advanced Science, EarlyView.
Palmitoylation by ZDHHC18 blocks ORF3a K27‐linked ubiquitination mediated by TRIM16, thereby preventing its proteasomal degradation and strengthening viral pathogenesis. Targeting palmitoylation through a pharmacological inhibitor (2‐BP), a competitive inhibitory peptide (OPIP), or adenovirus‐mediated knockdown of ZDHHC18 expression presents a ...
Sidi Yang, Kun Li, Lihong Liu, Linsen Zeng, Qifeng Deng, Jiacheng Huang, Xiaoran Dong, Xin Wang, Jianwei Liang, Hongchao Liu, Hong Peng, Yuxin Lin, Xiaolu Xie, Yuzhen Ye, Tiefeng Xu, Zhaohuan Wang, Chun‐Mei Li, Deyin Guo   +17 more
wiley   +1 more source

Gut Microbiome Communities Vary Across Translocated Populations of the Seychelles Warbler. [PDF]

Ecol Evol
Worsley SF, Crighton Z, Lee CZ, Burke T, Komdeur J, Dugdale HL, Richardson DS.   +6 more
europepmc   +1 more source

Mn‐Induced Support Stabilization and Ir Electronic Activation Enable Acid‐Stable, Low‐Loading IrO2 Water Oxidation

Advanced Science, EarlyView.
This study introduces a dual‐regulation strategy utilizing a Mn‐doped Co3O4 support to enhance the activity and stability of low‐loading IrO2 catalysts for acidic water oxidation. Mn induces strong Mn─O covalency to reinforce the spinel lattice and activates Ir sites via interfacial electron transfer.
Zhe Liu, Guoxin Ma, Shixiang Yu, Rui Jin, Fei Wang, Xinxin Wen, Mengxin Chen, Yani Ding, Jia Liu, Xinkai Guo, Diab Khalafallah, Hassan Fouad, Xiao Ren, Siwei Li   +13 more
wiley   +1 more source

Sporadic Appetites: Unearthing the Fungal Diets of Two Mycophagous Mammals Across an Australian Climate Gradient. [PDF]

Ecol Evol
Quah RJ, Cowen SJ, Davis RA, Mills HR, Hopkins AJM.   +4 more
europepmc   +1 more source

Large‐Scale Growth of Self‐Poled Ferroelectric Rashba Semiconductor α‐GeTe(111) Thin Films: A Crucial Step Towards Future CMOS‐Compatible Ferroelectric Spintronic Devices

Advanced Science, EarlyView.
Ferroelectric Rashba semiconductors promise ultralow‐power devices but lack industry‐quality films. This work demonstrates CMOS‐compatible fabrication of high‐quality α‐GeTe(111) films via magnetron sputtering, enabled by a 5 nm Sb2Te3 seed layer. Structural and ferroelectric analyses show robust, switchable polarization comparable to MBE films, paving
Jules Lagrave, Nicolas Bernier, Thomas Jalabert, Yoann Brûlé, Damien Térébénec, Pierre Meilleur, Hervé Roussel, Jean‐Baptiste Dory, Oussama J. Mouawad, Thibault Chommaux, Cristian Mocuta, Dominique Thiaudière, Laurent Vila, Françoise Hippert, Pierre Noé   +14 more
wiley   +1 more source

Population Structure of the Jewel Scarab Chrysina gloriosa. [PDF]

Genome Biol Evol
Sylvester T, Hjelmen CE, Thompson MJ, Blackmon LT, Alfieri JM, Hoover Z, Esfandani T, Blackmon H.   +7 more
europepmc   +1 more source