Results 51 to 60 of about 1,702,247 (305)
The Geopolitical Context of Chamorro Cultural Preservation in Guam, U.S.A. [PDF]
, 2012 An unincorporated Pacific Island territory of the United States, Guam has been under American rule since 1 898. While proudly Chamorro, the descendants of indigenous islanders have been American citizens since 1 950. U.S.
Diaz, Maria-Elena D.
core +1 more source
Island Studies Journal, 2017 Island studies has developed into an established, interdisciplinary research field. It is important that island studies not only continue deepening its internal theoretical understandings but also reach out to other fields and regions that have received limited attention within island studies.
openaire +3 more sources
E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer
Molecular Oncology, EarlyView.Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov +3 more
wiley +1 more source
BMJ Open, 2020 Objectives To determine if adults with overweight or obesity received counselling from their healthcare providers (HCPs) to lose weight and/or adopt healthful behaviours associated with weight loss, and whether they took action on their HCPs ...
Mary L. Greaney +4 more
doaj +1 more source
Contract law – The South Pacific: customary and introduced law [PDF]
, 2000 The author examines the practical effect of the combined influence of customary and introduced common laws on the law of contract operating in the South Pacific – particularly the twelve island countries within the region with membership of the ...
Care, Jennifer Corrin
core
DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling
FEBS Open Bio, EarlyView.Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang +7 more
wiley +1 more source
Island Studies Journal, 2(1), Book Reviews
Island Studies Journal, 2007 _Island Studies Journal_, 2(1), Book ...
Island Studies Journal
doaj +1 more source
The early Cycladic settlement at Dhaskalio, Keros: preliminary report of the 2008 excavation season [PDF]
, 2009 The 2008 excavations on the small island of Dhaskalio opposite Dhaskalio Kavos on the Cycladic island of Keros are reviewed. An account is given of the survey, recording many walls of the early Bronze Age, and of the excavations, continued from the 2007 ...
Brodie, N. +3 more
core +1 more source
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons +31 more
wiley +1 more source