Results 151 to 160 of about 2,636 (303)

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

Advanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao, Hai‐Jin Zeng, Zun Wang, Chun‐Gu Hong, Yi‐Juan Tan, Yan‐Xin Duan, Jing‐Yao Luo, Ming‐Jie Luo, Yi‐Wei Liu, Xin Wang, Yi Luo, Teng‐Fei Wan, Yong Zhou, Zheng‐Guang Wang, Guo‐Wen Hu, Hao Yin, Xin‐Yue Hu, Zhen‐Xing Wang, Ze‐Hui He, Si‐Yi Cheng, Wei Du, Zhe Guan, Hai‐Li Lang, Hong‐Ji Liu, Jia Cao, Peng Chen, Jiang‐Hua Liu, Hui Xie, Chun‐Yuan Chen   +28 more
wiley   +1 more source

Kinetic theory of island geodesic acoustic mode

Physics of Plasmas
We present a gyrokinetic theory of long-term collisionless damping of a self-generated monopolar E × B vortex flow in a tokamak magnetic island. By an explicit analytic calculation in the central island region, we show that the magnetic precession-induced coupling of the monopolar vortex to the island geodesic acoustic mode (IGAM) results in long-term ...
openaire   +1 more source

MEOX1 Coordinates Autocrine‐Paracrine Programs via SPHK1/S1P to Promote Lymph Node Metastasis in Ovarian Cancer

Advanced Science, EarlyView.
In ovarian cancer, MEOX1 activates the SPHK1/S1P pathway to promote both tumor progression and tumor–stroma crosstalk. MEOX1‐dependent signaling drives CAF activation, enhances VEGF‐C expression, and stimulates lymphangiogenesis, ultimately facilitating lymph node metastasis.
Jiajia Li, Xiuling Zhi, Qianhan Lin, Yating Sun, Yihua Sun, Zulimire Abudousalamu, Mengyang Xue, Chang Zheng, Xiaotian Li, Liangqing Yao, Mo Chen   +10 more
wiley   +1 more source

Comparative optimization of overcurrent relay coordination in DG-integrated distribution networks: water cycle algorithm versus genetic algorithm and big bang-big crunch. [PDF]

Sci Rep
Mohamed RE, Saleh SM, Ahmad AG.
europepmc   +1 more source

Epigenetic Silencing of RFX7 Defines a Transcriptional Axis Linking Lactate Metabolism to Immune Checkpoint Therapy in Glioblastoma

Advanced Science, EarlyView.
Glioblastoma (GBM) exhibits RFX7 silencing via promoter hypermethylation, which downregulates PIK3IP1 to activate PI3K/AKT signaling, increase lactate accumulation, and enhance histone H4K12 lactylation. This lactylation upregulates PD‐L1/CSF1 expression and drives the immunosuppressive microenvironment formation.
Liying Han, Jinpeng Zhou, Gang Zhu, Fan Chen, Leiyang Li, Wenxing Cui, Fang Sun, Tian Feng, Yue Zhang, Qiang Wang, Shuoyao Ma, Chengxuan Guo, Ziwen Zhang, Kai Wang, Jiahui Wang, Liangbo Wang, Wencong Li, Chenyi Yuan, Haixiao Liu, Liang Wang, Yan Qu   +20 more
wiley   +1 more source

Online event-triggered switching load frequency control of islanded microgrids through machine learning. [PDF]

Discov Electron
Omeje OU, Olukanni L, Okojie DE, Eya CU, Aina AB.   +4 more
europepmc   +1 more source

Engineering of Crystal and Domain Structures in Epitaxial Y:HfO2 Thin Films by YSZ Substrate Miscut

Advanced Science, EarlyView.
We investigate how YSZ substrate miscut influences crystal structure and domain formation in epitaxial Y‐doped HfO2 thin films. Using magnetron sputtering, high‐resolution X‐ray diffraction, atomic‐resolution scanning transmission electron microscopy, and first‐principles calculations, we systematically examine the characteristics of thickness‐ and ...
Jun Young Lee, Hyung‐Jin Choi, Kun Hee Ye, Haneul Choi, Byeong‐hyeon Lee, Min‐Seok Kim, Dong‐Hun Han, June Hyuk Lee, Sung Ok Won, Tae Heon Kim, Hye Jung Chang, Jung‐Hae Choi, Seung‐Hyub Baek   +12 more
wiley   +1 more source

Cost-effective and sustainable operation of microgrids using Improved Whale Optimization Algorithm. [PDF]

Sci Rep
El-Zaher SM, Ahmed AM, Ahmed EM, Sedki YT, Al-Muntaser HK, Sheta AN.   +5 more
europepmc   +1 more source

Epitaxial Stabilization of Ultrasmall Cu Nanoparticles With High‐Energy {110} Facets on Ti3C2 MXene for Efficient CO2‐to‐Acetate Electrocatalysis

Advanced Science, EarlyView.
Cu/Ti3C2 heterostructure: Cu/Ti3C2 heterostructure achieves epitaxial stabilization of high‐energy Cu(110) facets through lattice matching and electronic interaction, enabling efficient CO2 electroreduction to acetate with 42.5% Faradaic efficiency at 235 mA·cm−2. ABSTRACT The electrochemical CO2 reduction reaction (CO2RR) to multicarbon (C2+) products
Yan‐An Li, Jiapeng Huang, Yaohui Zhao, Junhao Lu, Yuan Ren, Zi‐Xin Ge, Qian Wang, Shangdong Ji, Yangzi Zheng, Chao Wu, Mingshang Jin   +10 more
wiley   +1 more source