Results 181 to 190 of about 652,541 (257)

Ultrasound‐Activatable Piezoelectric Hydrogel Reprograms Mitochondrial Epigenetics for Osteoarthritis Therapy via the mTOR/GATD3A Axis

Advanced Science, EarlyView.
An ultrasound‐activatable piezoelectric hydrogel reprograms chondrocyte mitochondrial epigenetics via the mTOR/GATD3A axis, clearing damaged mitochondria and alleviating osteoarthritis progression in both mouse models and human cartilage explants. ABSTRACT The avascular nature of cartilage hinders drug delivery for osteoarthritis (OA) therapy.
Hui Zheng, Pengfei Yan, Peng Liu, Chang Yan, Mengqi Zhao, Zuyong Wang, Chao Ma, Rongkai Zhang, Xi Cui, Swee Hin Teoh   +9 more
wiley   +1 more source

The effect of adsorbate induced surface strain on oxygen island formation on platinum surfaces.

Faraday Discuss
Nitz F, Kandratsenka A, Auerbach DJ, Kitsopoulos TN, Wodtke AM.   +4 more
europepmc   +1 more source

Modelling forest carbon stocks on the Canary Islands. [PDF]

Carbon Balance Manag
Otto R, García-Alvarado JJ, Rocafull E, Sierra Cornejo N, Irl SDH, Rodríguez Arvelo F, Ruíz-Peinado R, Fernández-Palacios JM, de Nascimento L.   +8 more
europepmc   +1 more source

EpCAM+ Extracellular Vesicle PD‐L1 Dynamics as a Predictive Biomarker of Immune Checkpoint Blockade Response

Advanced Science, EarlyView.
A highly sensitive SERS‐based platform measures PD‐L1 expression on EpCAM+ circulating EVs from cancer patients undergoing immunotherapy. Monitoring dynamic changes after treatment reveals that reduced EpCAM+ EV PD‐L1 levels associate with improved long‐term clinical outcomes, establishing a non‐invasive approach for tracking immune checkpoint ...
Byeonggeol Mun, Jinyoung Kim, Chang Gon Kim, Seokhyeong Go, Mina Han, Yujin Ouck, Soojin Jang, Seong Uk Son, Gamin Kim, Wonrak Son, Eunjung Kim, Min Hee Hong, Ja Hyun Yeo, Eun‐Kyung Lim, Hye Ryun Kim, Seungjoo Haam   +15 more
wiley   +1 more source

Computational analysis reveals historical trajectory of East Polynesian lunar calendars. [PDF]

PLoS One
Valério M, Tamburini F, Corazza M.
europepmc   +1 more source

Porcine Deltacoronavirus M Protein Binds NLRP3 to Promote Inflammasome Assembly via Competition with TRIM31

Advanced Science, EarlyView.
Porcine deltacoronavirus (PDCoV) infection induces severe intestinal inflammation and acute diarrhea in piglets, yet the molecular mechanism remains incompletely understood. The M protein activates NLRP3 inflammasome through dual mechanisms: direct binding to the NLRP3 LRR domain and disruption of TRIM31‐mediated K48‐linked ubiquitination.
Jinhui Hou, Fangfang Han, Anqi Liu, Yang Yu, Rui Zhao, Zhengting Shi, Yanrong Lv, Jinli Liu, Shaopo Zu, Zhanyong Wei, Jin Yuan, Hui Hu   +11 more
wiley   +1 more source

Unravelling the Interplay Between <i>Vairimorpha ceranae</i> and Viruses in Geographically Isolated Honey Bee (Apis mellifera) Populations. [PDF]

Evol Appl
Lopes AR, Low M, Martín-Hernández R, Higes M, de Miranda JR, Pinto MA.   +5 more
europepmc   +1 more source

Raman Evidence of Moiré Diamondene Formation by High‐Pressure

Advanced Science, EarlyView.
Two‐dimensional moiré diamondene is formed at approximately 2 GPa through the synergy of high pressure, interlayer twist, and a chemically active diamond (100) surface. It is a hybrid sp2–sp3 nanostructure, consists of localized nanodiamond domains and unbonded graphene segments.
Chaofeng Gao, Mingming Chang, Mengting Wang, Yu Chen, Shiyun Zheng, Jiankuan Wu, Min Chen, Keying Han, Luyuan Fan, Zhenxiao Zhang, Kun Zhai, Bochong Wang, Congpu Mu, Yingchun Cheng   +13 more
wiley   +1 more source

Fine-Scale Population Genomics Reveals Genetic Differentiation in the Brooding Amphipod <i>Cheirimedon femoratus</i> Across the South Shetland Islands, Antarctica. [PDF]

Ecol Evol
Jo E, Sepahvand V, Ahn YU, Kang S, Lamare M, Fraser C, Kim JH, Kim S.   +7 more
europepmc   +1 more source

Wafer‐Scale Atomically‐Thin Gold: Transferable Platform for Flexible Optoelectronics, Thermal Management and Bio‐Interfaces

Advanced Science, EarlyView.
Combining template stripping with a graphene‐inspired transfer yields continuous, transferable gold films at 6‐inch wafer scale with thicknesses approaching the atomic limit. The atomically smooth, near‐bulk‐quality films offer above 86% transmittance and sub‐20 Ω/square sheet resistance, serving as a universal platform for flexible optoelectronics ...
Dmitry Yakubovsky, Mikhail Mironov, Georgy Ermolaev, Aleksandr Khrebtov, Aleksandr Slavich, Prashant Narute, Pritom Chowdhury, Roman Kirtaev, Igor Khramtsov, Anton Minnekhanov, Gleb Tselikov, Dmitriy Grudinin, Maria Sidorova, Nikolay Pak, Pavel Maslov, Andrey Vyshnevyy, Hongkai Zhou, Vasyl G. Kravets, Alexander N. Grigorenko, Ivan Kruglov, Nikita Orekhov, Dmitry Kireev, Aleksey Arsenin, Kostya S. Novoselov, Valentyn Volkov   +24 more
wiley   +1 more source