Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
Migration Dilemmas of Islanders: Commuting Leading to Migration or Remaining at Home
The paper presents and discusses the results of an empirical survey carried out in April 2000 on the islands Prvić, Zlarin and Krapanj in the Šibenik coastal area.
Ivan Lajić +2 more
doaj
Present and Future of the White‐Tailed Laurel Pigeon (Columba junoniae) on Gran Canaria Island
Due to their evolutionary history and restricted distribution islands species are particularly vulnerable to human impacts and extinction. Consequently, many islands' species have been extirpated, causing complete or local extinctions.
Gonzalo Albaladejo‐Robles +2 more
doaj +1 more source
Automating nested watershed delineation over the world considering endorheic basins and islands
Global-scale nested watershed datasets are foundational for hydrological studies. However, their construction is not yet fully automated, making the process labor-intensive and time-consuming, primarily due to the lack of algorithms capable of encoding ...
Junzhi Liu +5 more
doaj +1 more source
The diversity and distributions of the beetles (Insecta: Coleoptera) of the northern Leeward Islands, Lesser Antilles (Anguilla, Antigua, Barbuda, Nevis, Saba, St. Barthélemy, St. Eustatius, St. Kitts, and St. Martin-St. Maarten [PDF]
This paper summarizes the published information on the beetle fauna of the northern Leeward Islands (Anguilla, Antigua, Barbuda, Nevis, Saba, St. Barthélemy, St. Eustatius, St. Kitts, St. Martin-St.
Peck, Stewart B.
core +3 more sources
Discovery and Targeted Proteomic Studies Reveal Striatal Markers Validated for Huntington's Disease
ABSTRACT Objective Clinical trials for Huntington's disease (HD) enrolling persons before clinical motor diagnosis (CMD) lack validated biomarkers. This study aimed to conduct an unbiased discovery analysis and a targeted examination of proteomic biomarkers scrutinized by clinical validation. Methods Cerebrospinal fluid was obtained from PREDICT‐HD and
Daniel Chelsky +8 more
wiley +1 more source
SummaryAn artificial island in eastern Turkey created by a team of biologists is proving a haven for wildlife. Nigel Williams reports.
openaire +2 more sources
Cutaneous Phosphorylated Alpha‐Synuclein in Lewy Body Dementia
ABSTRACT Objective To determine the test performance of cutaneous phosphorylated alpha‐synuclein (P‐SYN) in dementia with Lewy bodies (DLB), individuals with reduced Montreal Cognitive Assessment (MoCA) and healthy controls. Methods This is the first subgroup analysis of the Synuclein‐One study, a prospective, blinded study evaluating P‐SYN detection ...
Christopher H. Gibbons +31 more
wiley +1 more source
Scaling of Heteroepitaxial Island Sizes
Monte Carlo simulations of an atomistic solid-on-solid model are used to study the effect of lattice misfit on the distribution of two-dimensional islands sizes as a function of coverage $\Theta$ in the submonolayer aggregation regime of epitaxial growth.
A. Zangwill +22 more
core +2 more sources
Vestibular Patient Journey: Insights From Vestibular Disorders Association (VeDA) Registry
ABSTRACT Objective Vestibular symptoms impose a high burden of disability. Understanding real‐world diagnostic and treatment pathways can identify care gaps and guide interventions. We aimed to characterize symptom profiles, diagnostic trends, provider involvement, and treatment patterns in vestibular disorders.
Ali Rafati +10 more
wiley +1 more source

