Results 111 to 120 of about 99,971 (348)

Elbow dimensions in quadrupedal mammals driven by lubrication regime

open access: yesScientific Reports
Synovial joints, such as the elbow, experience different lubrication regimes, ranging from fluid film to boundary lubrication, depending on locomotion conditions.
Kalenia Marquez-Florez   +3 more
doaj   +1 more source

Trojan Horse Strategy: How Biomimetic Nanomedicine Remodels the Tumor Microenvironment

open access: yesAdvanced Science, EarlyView.
This review focuses on biomimetic nanomedicines for tumor microenvironment (TME) remodeling, covering their diverse biomimetic types, design principles, and mechanisms of immune cell reprogramming and reversal of immunosuppressive microenvironments, with particular emphasis on their application in synergistic immunotherapy.
Wanrong Wang   +7 more
wiley   +1 more source

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis

open access: yesAdvanced Science, EarlyView.
A synergistic electron transfer (ET) optimization strategy modulating conformational dynamics, ET pathway, and substrate orientation is proposed for self‐sufficient cytochrome P450s. Guided by this strategy, a P450 variant with improved ET and catalytic efficiency was identified, and the underlying molecular basis was revealed by computational analysis.
Ziqi Liang   +9 more
wiley   +1 more source

Hypergravity is more challenging than microgravity for the human sensorimotor system

open access: yesnpj Microgravity
The importance of gravity for human motor control is well established, but it remains unclear how the central nervous system accounts for gravitational changes to perform complex motor skills.
Loïc Chomienne   +3 more
doaj   +1 more source

Gutmann Donor Theory‐Guided Design of Mononuclear Ionic Cluster for Exceptional N‐Type Thermoelectric Ionogel

open access: yesAdvanced Science, EarlyView.
Super‐stretchable and self‐healing polyacrylate ternary ionogel elastomers are used for flexible i‐TE devices. Based on Gutmann donor theory of doped anion, the work proposes a three‐parameter tuning strategy of flexible polymer‐doped anion‐synergistic cation to achieve the systematic design of ionic thermoelectric materials. Abstract Quasi‐solid‐state,
Bin Chen   +9 more
wiley   +1 more source

Cascade‐Responsive MXene@Cu‐MOF Heterostructure Integrates Antioxidant Activity, Infection Control, and Vascularization for Tracheal Repair

open access: yesAdvanced Science, EarlyView.
A cascade‐responsive MXene@Cu‐MOF/GelMA hydrogel is engineered as a “skeleton–backpack” platform for extensive tracheal repair. The MXene framework scavenges postoperative ROS and converts NIR light into mild hyperthermia, while the Cu‐MOF component provides pH/NIR‐responsive Cu2+ dosing for infection control, angiogenesis, and chondrogenesis.
Liang Guo   +8 more
wiley   +1 more source

Persistent Magnetism and Tunable Doping of Monolayer Graphene via Europium Density Modulation

open access: yesAdvanced Science, EarlyView.
The modulation of europium density at the graphene/rhenium interface enables electron doping of monolayer graphene both beneath and beyond the van Hove singularity. The interfacial europium is ferromagnetic, with a transition from a mixed Eu(II)/Eu(III) valence in the dense phase to a pure Eu(II) state in the diluted phase.
M. Jugovac   +9 more
wiley   +1 more source

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