Results 231 to 240 of about 68,056 (282)

Lipid Metabolism Optimisation in Ashbya gossypii to Produce Microbial Oils From Xylose‐Rich Feedstocks

Microbial Biotechnology, Volume 18, Issue 8, August 2025.
A multigenic strategy enhanced lipid production in a xylose‐utilising strain of Ashbya gossypii by boosting acetyl‐CoA and NADPH supply while blocking β‐oxidation. The engineered strain reached 60% oil content when grown on sugar mixtures simulating xylose‐rich feedstocks.
Javier‐Fernando Montero‐Bullón, Javier Martín‐González, Gloria Muñoz‐Fernández, Rubén M. Buey, Alberto Jiménez   +4 more
wiley   +1 more source

Isocitrate Dehydrogenase (IDH)-Mutant High-Grade Glioma in the Cerebellum: A Case Report. [PDF]

Cureus
Dinesh D, Johnson T, P K D, Rengarajan S, Indiran V.   +4 more
europepmc   +1 more source

Recurrent hypoglycemia exposure increases the risk of platelet activation and thrombosis in insulin‐treated diabetic rats

Diabetes, Obesity and Metabolism, Volume 27, Issue 8, Page 4126-4136, August 2025.
Abstract Aims Diabetes is a widespread disease associated with long‐term complications. Treatment of diabetes alleviates these complications but cause an increased risk of recurrent hypoglycemia (RH). Hypoglycemia exposure increases the risk of cardiovascular events by an unknown mechanism.
Ashish K. Rehni, Sunjoo Cho, Allen Liu, Jonathan Lo, Stephanie S. Kim, Nathalie Khoury, Miguel A. Perez‐Pinzon, Wenche Jy, Kunjan R. Dave   +8 more
wiley   +1 more source

DegS regulates the aerobic metabolism of Vibrio cholerae via the ArcA-isocitrate dehydrogenase pathway for growth and intestinal colonization. [PDF]

Front Cell Infect Microbiol
Zhao J, Huang X, Li Q, Ren F, Hu H, Yuan J, Wang K, Hu Y, Huang J, Min X.   +9 more
europepmc   +1 more source

Diagnostic Performance of ChatGPT‐4.0 in Histopathological Analysis of Gliomas: A Single Institution Experience

Neuropathology, Volume 45, Issue 4, August 2025.
ABSTRACT This study aimed to evaluate the performance of ChatGPT‐4.0 as a diagnostic support tool for pathologists in identifying different types of gliomas based on histopathological data and to compare its performance with that of another artificial intelligence tool (Gemini 2.5 Pro).
Manuel Mazzucchelli, Serena Salzano, Rosario Caltabiano, Gaetano Magro, Francesco Certo, Giuseppe Barbagallo, Giuseppe Broggi   +6 more
wiley   +1 more source

Using partially shared radiomics features to simultaneously identify isocitrate dehydrogenase mutation status and epilepsy in glioma patients from MRI images. [PDF]

Sci Rep
Wang Y, Gao A, Yang H, Bai J, Zhao G, Zhang H, Song Y, Wang C, Zhang Y, Cheng J, Yang G.   +10 more
europepmc   +1 more source

Recent advances in the structure, function and regulation of the volume‐regulated anion channels and their role in immunity

The Journal of Physiology, Volume 603, Issue 15, Page 4255-4291, 1 August 2025.
Abstract figure legend The volume‐regulated anion channel (VRAC), composed of leucine‐rich repeat‐containing 8 (LRRC8) proteins, serves both canonical and non‐canonical functions in vertebrate cells. The canonical function of this channel relates to its original description, which is homeostatic regulation of cell volume in response to hypotonic ...
Sergei Yanushkevich, Aleksandra Zieminska, Joshua Gonzalez, Francisca Añazco, Richard Song, Alejandra Arias‐Cavieres, Sara T. Granados, Junyi Zou, Yan Rao, Axel R. Concepcion   +9 more
wiley   +1 more source

Molecular diversity in isocitrate dehydrogenase-wild-type glioblastoma. [PDF]

Brain Commun
Fares J, Wan Y, Mair R, Price SJ.
europepmc   +1 more source

Targeting Isocitrate Dehydrogenase (IDH) in Solid Tumors: Current Evidence and Future Perspectives. [PDF]

Cancers (Basel)
Carosi F, Broseghini E, Fabbri L, Corradi G, Gili R, Forte V, Roncarati R, Filippini DM, Ferracin M.   +8 more
europepmc   +1 more source

Diagnosis of Isocitrate Dehydrogenase-Mutant Astrocytoma in the Subcallosal Gyrus Using T2-Fluid-Attenuated Inversion Recovery Mismatch Sign and Quantitative Magnetic Resonance Relaxometry. [PDF]

Cureus
Tajima Y, Yuzawa S, Kanemura Y, Tanino M, Kinoshita M.   +4 more
europepmc   +1 more source