Results 241 to 250 of about 358,941 (349)

Isocitrate dehydrogenase and related oxidative decarboxylases [PDF]

FEBS Letters, 1980
openaire   +2 more sources

mTORC1‐USP30‐LEF1 Cascade Regulates Cancer Stemness and Malignant Progression Through Mitonuclear Crosstalk

MedComm, Volume 6, Issue 12, December 2025.
Nutrient deprivation triggers USP30 nuclear translocation via an N‐terminal nuclear localization signal (NLS), mediated through suppression of mTORC1‐dependent phosphorylation at serine 104, a modification constraining nuclear entry. Nuclear USP30 deubiquitinates TCF/LEF1 at K379 and K382 residues, disrupting recruitment of CBP/P300 co‐activators to ...
Xiaolin Li, Haowei Zhang, Jia Li, Cheng Luo, Zijian Yang, Jin Cai, Li Xia, Yapei Jiang, Ruonan Wang, Hongli Zeng, Yuetong Li, Haitao Yang, Tong Gao, Weidong Xie, Yaou Zhang, Naihan Xu   +15 more
wiley   +1 more source

Assessing the predictability of isocitrate dehydrogenase mutational status in glioma patients using imaging features. [PDF]

Surg Neurol Int
Goncalves JM, Miranda A, Silva C, Carvalho B, Polónia P, Linhares P.   +5 more
europepmc   +1 more source

Musculoskeletal Diseases: Mechanisms and Therapeutic Advances

MedComm, Volume 6, Issue 12, December 2025.
Musculoskeletal diseases comprise a broad spectrum of inflammatory, degenerative, and neoplastic disorders. Increasing evidence highlights the central role of immune regulation in their pathogenesis, with complex interactions among immune, bone, muscle, and stromal cells.
Xiao Ma, Eloy Yinwang, Xupeng Chai, Fangqian Wang, Zehao Chen, Shengdong Wang, Hao Zhou, Yucheng Xue, Jiangchu Lei, Fanglu Chen, Hengyuan Li, Shixin Chen, Shenzhi Zhao, Kelei Wang, Liang Chen, Junjie Gao, Zhaoming Ye, Nong Lin   +17 more
wiley   +1 more source

<i>C. elegans</i> Cytoplasmic Isocitrate Dehydrogenase Neomorphic G98N and R133H Mutants Produce the Oncometabolite 2-Hydroxyglutarate. [PDF]

Int J Mol Sci
Bouchard M, McAllister A, Bourlett NS, Hoyt C, Calcul L, Walstrom KM.   +5 more
europepmc   +1 more source

Global health status and fatigue score in isocitrate dehydrogenase-mutant diffuse glioma grades 2 and 3: A longitudinal population-based study from surgery to 12-month follow-up [PDF]

Tomás Gómez Vecchio, Isabelle Rydén, Anneli Ozanne, Malin Blomstrand, Louise Carstam, Anja Smits, Asgeir Store Jakola   +6 more
openalex   +1 more source

378. Isocitrate Dehydrogenase 2 Overexpression Ameliorates Ischemia Reperfusion Injury to the Kidney [PDF]

, 2015
Devin Bready, Peter R. Corridon, Shijun Zhang, David P. Basile, Robert L. Bacallao, Simon J. Atkinson   +5 more
openalex   +1 more source

Targeting Metabolic Reprogramming in Tumor: From Mechanisms to Precision Immunotherapies

MedComm – Oncology, Volume 4, Issue 4, December 2025.
Cancer metabolic reprogramming is a key hallmark of tumorigenesis and antitumor immunity. It boosts tumor progression by enhancing cancer cell fitness in hostile microenvironments and facilitates immune evasion by evading natural and therapy‐driven antitumor immune responses.
Tong Zhang, Ping Gao, Linchong Sun
wiley   +1 more source

The utility of multi-b-value diffusion and arterial spin labelling magnetic resonance imaging in gliomas grading and prediction of isocitrate dehydrogenase status. [PDF]

Quant Imaging Med Surg
Kopřivová T, Dostál M, Jůza T, Vybíhal V, Neuman E, Ovesná P, Kozubek M, Keřkovský M.   +7 more
europepmc   +1 more source

Suppression of metabolic defects of yeast isocitrate dehydrogenase and aconitase mutants by loss of citrate synthase

, 2008
An-Ping Lin, Kevin Hakala, Susan T. Weintraub, Lee McAlister-Henn   +3 more
openalex   +1 more source