Results 191 to 200 of about 301,160 (383)

Neuroprotective effects of dexmedetomidine against isoflurane-induced neuronal injury via glutamate regulation in neonatal rats

open access: yesDrug Design, Development and Therapy, 2018
Xue Wang,1,2,* Yangyang Shan,1,* Zhiyin Tang,1 Linlin Gao,3 Hongtao Liu1 1Department of Anesthesiology, Shengjing Hospital, China Medical University, Shenyang 110004, China; 2Department of Anesthesiology, Xiangyang Central Hospital, Affiliated Hospital ...
Wang X, Shan Y, Tang Z, Gao L, Liu H
doaj  

Cytokine mRNA Delivery and Local Immunomodulation in the Placenta Using Lipid Nanoparticles

open access: yesAdvanced Therapeutics, EarlyView.
This article evaluates lipid nanoparticles to deliver immunomodulatory mRNA to placental cells and mouse placentas to study and treat the immune underpinnings of placenta‐related diseases. Lipid nanoparticles induce cytokine secretion and macrophage polarization toward an anti‐inflammatory state.
Samuel I. Hofbauer   +9 more
wiley   +1 more source

The effects of halothane and isoflurane on cardiovascular function in laterally recumbent horses [PDF]

open access: yes, 2005
A.L. Raisis   +38 more
core   +1 more source

SMYD3 Promotes Immune Evasion in Clear Cell Renal Cell Carcinoma via SREBP1‐Mediated Transactivation of CD47

open access: yesAdvanced Science, EarlyView.
Cancer cell‐intrinsic SMYD3 orchestrates an immunosuppressive microenvironment and impairs the response to PD‐1 blockade by reprogramming immune cells landscape in the tumor microenvironment of clear cell renal cell carcinoma (ccRCC). The immunomodulatory function of SMYD3 is mediated via the SREBP1/CD47 pathway.
Zhengfang Liu   +14 more
wiley   +1 more source

Lecithin Alleviates Memory Deficits and Muscle Attenuation in Chinese Older Adults and SAMP8 Mice

open access: yesAdvanced Science, EarlyView.
This study opens a new avenue for safeguarding cognition and muscle health, averting disability in older age, and treating age‐related pathologies through lecithin supplementation. It serves as a promising nonpharmacological intervention for the crosstalk of muscle and cognition.
Xianyun Wang   +16 more
wiley   +1 more source

Effects of Isoflurane on Coronary Arteries and Coronary Arterioles in the Intact Dog [PDF]

open access: bronze, 1987
J. C. Sill   +5 more
openalex   +1 more source

Alnustone Ameliorates Metabolic Dysfunction‐Associated Steatotic Liver Disease by Facilitating Mitochondrial Fatty Acid β‐Oxidation via Targeting Calmodulin

open access: yesAdvanced Science, EarlyView.
This study identifies alnustone, a natural compound from Alpinia katsumadai, as a potent therapeutic agent for MASLD and MASH. Alnustone enhances mitochondrial fatty acid β‐oxidation by directly targeting calmodulin, improving liver steatosis, fibrosis, and insulin resistance in vivo.
Shourui Hu   +13 more
wiley   +1 more source

Cerebrovascular Responsiveness to Carbon Dioxide in Dogs with 1.4% and 2.8% Isoflurane [PDF]

open access: bronze, 1989
Robert W. McPherson   +2 more
openalex   +1 more source

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