Results 191 to 200 of about 35,183 (294)

Ultrasound‐Assisted H2 Transmitter Enables Hydrogen‐Gene Therapy to Prevent Anesthesia/Surgery‐Induced Cognitive Impairment

Advanced Science, EarlyView.
Postoperative cognitive dysfunction (POCD) remains a challenge with no effective treatments. This study introduces a novel hydrogen‐gene therapy strategy, combining focused ultrasound and siRNA delivery via hydrogen emitters, to repair neuroinflammation in a precise and controlled manner.
Ruonan Zhan, Yan Fang, Chuyun Lou, Nan Chen, Xuan Mo, Bo Jiao, Mengke Liu, Yangxi Zhao, Weichen Xu, Huixiong Xu, Haohao Yin, Yi Zhang   +11 more
wiley   +1 more source

Cardiovascular Effects of Inhalation Induction with Isoflurane in Infants

, 1983
Robert H. Friesen, J. Lance Lichtor
openalex   +1 more source

Alterations of Alpha1 and Alpha2 Adrenoceptor-mediated Pressor Responses by Halothane and Isoflurane Anesthesia [PDF]

, 1989
Dermot Kenny, Lorie R. Pelc, Harold L. Brooks, John P. Kampine, William T. Schmeling, David C. Warltier   +5 more
openalex   +1 more source

Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS‐Induced Depressive‐Like Behaviors

Advanced Science, EarlyView.
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao, Zhongkun Zhang, Minzi Ju, Liang Bian, Huijuan Wang, Sibo Zhao, Ningbo Cai, Yu Wang, Yanpeng Jia, Ling Shen, Yuan Zhang, Honghong Yao   +11 more
wiley   +1 more source

Isoflurane preconditioning induced genomic changes in mouse cortex

BJA Open
Background: Altered patterns of genetic expression induced by isoflurane preconditioning in mouse brain have not yet been investigated. The aim of our pilot study is to examine the temporal sequence of changes in the transcriptome of mouse brain cortex ...
Umeshkumar Athiraman, Tusar Giri
doaj  

Increased Sensitivity of the Isometric Contraction of the Neonatal Isolated Rat Atria to Halothane, Isoflurane, and Enflurane [PDF]

, 1986
Chalapathi Rao, Michael S. Boyer, Gopal Krishna, Raymond R. Paradise   +3 more
openalex   +1 more source

Catheter Injectable Multifunctional Biomaterial for the Treatment of Infected Enterocutaneous Fistulas

Advanced Science, EarlyView.
A multi‐functional shear‐thinning hydrogel is engineered to treat enterocutaneous fistulas. This hydrogel can resist external pressures allowing it to remain within the fistula tract and is shown to have significant antimicrobial, pro‐healing, and anti‐inflammatory properties, which were validated in in vitro and in vivo experiments.
Jinjoo Kim, Zefu Zhang, Hassan Albadawi, Hyeongseop Keum, Joseph L. Mayer, Erin H. Graf, Rahmi Oklu   +6 more
wiley   +1 more source

An In Vivo 19F Nuclear Magnetic Resonance Study of Isoflurane Elimination from the Rabbit Brain

, 1987
Pamela Mills, Daniel I. Sessler, Michael E. Moseley, W Chew, Brian J.G. Pereira, Thomas Leroy James, Lawrence Litt   +6 more
openalex   +1 more source

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source

RECOVERY FROM OUTPATIENT ANAESTHESIA: A COMPARISON OF INCREMENTAL PROPOFOL AND PROPOFOL-ISOFLURANE

, 1987
K. R. Milligan, D. P. O’Toole, J. Howe, Joanna Cooper, JOHN W. DUNDEE   +4 more
openalex   +1 more source