Results 191 to 200 of about 218,062 (252)

Critical Care Sedation: Emerging Clinical Considerations and Risks of Volatile Anesthetics for Sedation: A Narrative Review. [PDF]

Diseases
Breaux AM, Miller GR, Cooper HD, Bembenick KN, Reddy A, Ahmadzadeh S, Shekoohi S, Kaye AD.   +7 more
europepmc   +1 more source

PEAR1 Promotes Glucose Metabolism Reprogramming in Sepsis‐Associated Acute Lung Injury via AARS1‐Mediated HIF‐1α Lactylation

Advanced Science, EarlyView.
This study revealed that a PEAR1/HIF‐1α/ glycolysis/lactate/H3K18la positive feedback loop in PMVECs that drives the development of S‐ALI. Mechanistically, PEAR1 mediates the binding of HIF‐1α to AARS1, leading to the lactylation of HIF‐1α, the primary lactylation site of which is K172.
Shuai Li, Zongqing Lu, Pu Fang, Qingqing Pang, Xianghui Wu, Bo Wang, Min Liang, Jingjing Pan, Haobo Kong, Haijian Cai, Juanjuan Li, Jiaying Kang, Dongsheng Wang, Dunling Xia, Mengmeng Xu, Qinghai You   +15 more
wiley   +1 more source

Atopic march protocol involving sequential skin and lung inflammation elicited by epicutaneous Staphylococcus aureus and allergen exposure. [PDF]

STAR Protoc
Kline SN, Feller LE, Wills D, Damarla R, Archer NK.   +4 more
europepmc   +1 more source

Structural Polymorphism of polyG Inclusions Revealed by In Situ Cryo‐Electron Tomography

Advanced Science, EarlyView.
Correlative cryo‐electron tomography in primary cortical neurons and NIID mouse brain tissue reveals that polyG inclusions are interconnected ribbon‐like assemblies rather than canonical amyloid fibrils. Multiple compartment‐specific ribbon states show distinct 26S proteasome accessibility, while cytoplasmic ribbons contact and deform ER‐like ...
Yunwen Qian, Yalan Wan, Chen Chen, Xiaoyu Zheng, Wenjing Du, Junhan Yang, Zhihao Quan, Biyu Yang, Jiaxi Yu, Jie Zheng, Zhaoxia Wang, Jianwen Deng, Qiang Guo   +12 more
wiley   +1 more source

Protocol to interrogate the role of creeping fat and mechanical tension in Crohn's disease using a surgical mouse model of intestinal fibrosis. [PDF]

STAR Protoc
Suh EJ, Pham B, Bauer-Rowe KE, Kim A, Liang NE, Park JY, Foster DS, Norton JA, Delitto D, Longaker MT, Hyun JS.   +10 more
europepmc   +1 more source

Comparison of the Effects of Sevoflurane and Isoflurane During Liver Transplant Surgery on the Short-Term Cardiac, Hepatic, and Renal Outcome: A Randomized Clinical Trial. [PDF]

Iran J Pharm Res
Moshari M, Tahery S, Dahi Taleghani M, Dabir S, Vosoughian M, Tabashi S, Ariannik M, Madadi F.   +7 more
europepmc   +1 more source

Isoflurane and Surgical Stress Disrupt Fatty Acid and Carbon Metabolism, Leading to Cardiomyopathy in Aged Mice. [PDF]

Cells
Yang WW, Chen AW, Lee H, Li H, Lee JG, Li Y, Shen WB.   +6 more
europepmc   +1 more source

Impact of different anesthetics on ischemia reperfusion injuries in patients undergoing hepatectomy: a network meta-analysis. [PDF]

Front Med (Lausanne)
Wang S, Tian F, Zhang R, Deng Z, Zhou L, Ren L, Wu F.   +6 more
europepmc   +1 more source

The dual effects of anesthetics on glial cells: a review of neuroprotection and neurotoxicity. [PDF]

Front Pharmacol
Wang X, Zhao M, Liu Z.
europepmc   +1 more source