Results 241 to 250 of about 228,231 (339)

The cryo-EM structure and physical basis for anesthetic inhibition of the THIK1 K2P channel. [PDF]

Proc Natl Acad Sci U S A
Riel EB, Bu W, Joseph TT, Khajoueinejad L, Eckenhoff RG, Riegelhaupt PM.   +5 more
europepmc   +1 more source

Isoflurane-induced Apoptosis of Neurons and Oligodendrocytes in the Fetal Rhesus Macaque Brain

Anesthesiology, 2014
C. Creeley, K. Dikranian, G. Dissen, S. Back, J. Olney, A. Brambrink   +5 more
semanticscholar   +1 more source

Ultrasound‐Induced Nitric Oxide‐Propelled Nanomotor for Multimodal Theranostics of Cancer with Deep Penetration and Extended Lifetime

Advanced Science, EarlyView.
A hollow nanomotor (PM‐HMSN/Arg) propelled by ultrasound‐triggered nitric oxide (NO) was developed. The nanomotor employs a “tethering‐relaxing‐drilling” mechanism to overcome biological barriers, enabling multimodal theranostics of cancer with deep penetration and extended lifetime.
Xue Xu, Jinxu Cao, Yan Mu, Hao Zhang, Ya‐Lei Wang, Mengzhen Chen, Yuce Li, Qian Hua   +7 more
wiley   +1 more source

Inhaled sedation versus propofol in respiratory failure in the ICU (INSPiRE-ICU2): study protocol for a multicenter randomized controlled trial. [PDF]

Trials
O'Gara B, Serra AL, Englert JA, Sachdev A, Owens RL, Chang SY, Park PK, Talmor D, Sverud I, Sackey P, Beitler JR.   +10 more
europepmc   +1 more source

Designer receptor manipulations reveal a role of the locus coeruleus noradrenergic system in isoflurane general anesthesia

Proceedings of the National Academy of Sciences of the United States of America, 2014
Elena M. Vazey, G. Aston-Jones
semanticscholar   +1 more source

Semaphorin 3E‐Plexin‐D1 Pathway Downstream of the Luteinizing Hormone Surge Regulates Ovulation, Granulosa Cell Luteinization, and Ovarian Angiogenesis in Mice

Advanced Science, EarlyView.
The Semaphorin 3E (Sema3E)‐Plexin‐D1 pathway mediated by C/EBPα and C/EBPβ downstream of the luteinizing hormone (LH) surge plays important roles in the mouse preovulatory ovary. Timely activation and suppression of this pathway during the preovulatory stage are crucial for ovulation, corpus luteum formation, and proper angiogenesis.
Hanxue Zhang, Jimmy Dhillon, Paul D. Soloway, Bo Shui, Seoyeon Lee, Jennifer K. Grenier, Paul R. Munn, M. Cecilia Ljungberg, Rebecca B Williams, Rainer B. Lanz, Yu‐Hsiang Liao, Yi A. Ren   +11 more
wiley   +1 more source

Label-free and fluorescence imaging of oligodendrocytes and myelin. [PDF]

Npj Imaging
Kamen Y, Doty ME, Ciolkowski ME, Bame X, Pietramale AN, Schain AJ, Grutzendler J, Hill RA.   +7 more
europepmc   +1 more source

Discovery of Natural Compound α‐Hederin via Large‐Scale Screening as a Targeted JAK/STAT3 Inhibitor for Ovarian Cancer Therapy

Advanced Science, EarlyView.
This study identifies α‐Hederin as a potent dual JAK1/JAK2 inhibitor that blocks STAT3 activation in ovarian cancer. By disrupting STAT3‐driven transcriptional programs, α‐Hederin suppresses tumor proliferation, invasion, and EMT, while enhancing cisplatin efficacy and overcoming chemoresistance.
Jiayu Wang, Pengzhan He, Cheng Liu, Xin Chen, Yilin Tan, Rui Qu, Yan Zhang, Zhou Li, Tailang Yin, Zhinang Yin   +9 more
wiley   +1 more source

Multi-scenario photoacoustic endoscopy for <i>in vivo</i> functional imaging. [PDF]

Photoacoustics
Liang X, Zhao Y, Li L, Sun H, Qin W, Li T, Guo H, Qi W, Xi L.   +8 more
europepmc   +1 more source

EFFICACY OF VECURONIUM BY CONTINUOUS INFUSION WITH EITHER ISOFLURANE OR FENTANYL-NITROUS OXIDE ANESTHESIA

, 1988
Timothy J. Quill, Peter S. A. Glass, C A Beach   +2 more
openalex   +1 more source