Results 261 to 270 of about 228,231 (339)

Time‐dependent effects of isoflurane and dexmedetomidine on functional connectivity, spectral characteristics, and spatial distribution of spontaneous BOLD fluctuations

NMR in Biomedicine, 2014
M. Magnuson, G. Thompson, W. Pan, S. Keilholz   +3 more
semanticscholar   +1 more source

An Engineered Soluble Single‐Chain TCR Engager for KRAS‐G12V Specific Tumor Immunotherapy

Advanced Science, EarlyView.
This study develops a dimeric T cell receptor engager protein specific for tumor KRAS‐G12V mutation. The engager proteins are capable of mediating the formation of synapse between T cell and tumor cell and demonstrate substantial tumor suppression efficacy.
Keke Ma, Jie Wang, Min Jiang, Juanhua He, Fangyang Li, Dan Lu, Chao Su, Yan Chai, Wenjing Jin, Yu Chen, Catherine W.H. Zhang, Xiaopeng Ma, Hui Tan, George F. Gao, Shuguang Tan   +14 more
wiley   +1 more source

Contactless monitoring of respiratory rate variability in rats under anesthesia with a compact 24GHz microwave radar sensor. [PDF]

Front Vet Sci
Sun G, Kurosawa M, Ninomiya Y, Baba K, Son NH, Yen HT, Suzuki S, Kano Y.   +7 more
europepmc   +1 more source

Nanoparticle‐Mediated CXCL12–CXCR4 Inhibition Reprograms Macrophages and Suppresses Gastric Carcinoma

Advanced Science, EarlyView.
Molecular mechanism study of self‐assembled M2pep‐Cs NPs/Plerixafor nanoparticles in targeting MΦ reprogramming by regulating the CXCL12–CXCR4 signaling pathway to enhance immune recognition and clearance of GC (Created by BioRender). Abstract Gastric carcinoma (GC) remains a major global health challenge, requiring novel therapeutic approaches.
Qianqian Cao, Xiaolei Cheng, Rongbin Lv, Dianshui Sun, Jihua Wang, Runjia Fu, Rumei Gong, Yueying Xiao, Qin Liu, Xiaomei Li   +9 more
wiley   +1 more source

Anesthetic choice impacts mortality and bacterial clearance in a murine experimental pneumonia model. [PDF]

BMC Infect Dis
Gage H, Hannah SM, Hancock B, Cornax I, Munguia J, Olson J, Bjånes E, Zurich R, Hoffman A, Askarian F, Tong K, Liu L, Nizet V, Meier A.   +13 more
europepmc   +1 more source

Calcitonin Gene‐Related Peptide (CGRP)‐Expressing Neurons in the External Lateral Parabrachial Area Regulate Pain‐Induced Sleep Disturbances

Advanced Science, EarlyView.
Lynch et al., identified novel targets on the wake‐promoting pathways that can effectively treat pain‐induced sleep disturbances. The authors demonstrated that Calcitonin gene‐related peptide‐expressing neurons (CGRP) in the external lateral parabrachial nucleus (PBelCGRP) serve as the primary relay node for pain stimuli that cause sleep disruption ...
Nicole Lynch, Roberto De Luca, Richard L Spinieli, Enrico Rillosi, Renner C Thomas, Samuel Sailesh, Nishta Gangeddula, Janayna D Lima, Sathyajit S Bandaru, Elda Arrigoni, Agustin Melo‐Carrillo, Rami Burstein, Stephen Thankachan, Satvinder Kaur   +13 more
wiley   +1 more source

Microtubule-modulating drugs alter sensitivity to isoflurane in mice. [PDF]

BMC Anesthesiol
Li N, You Z, Ren Y, Kim HH, Yang J, Li G, Doheny JT, Ding W, Xia S, Wang S, Zhou X, Wu X, Shen S, Dong Y, Xie Z, Chen L, Mao J, Martyn JAJ.   +17 more
europepmc   +1 more source

Minimally Invasive Chemical Biopsy Needle with Self‐Wettable Extraction Phase For In Vivo Tissue Sampling During Medical Procedures

Advanced Science, EarlyView.
A new tissue sampling device using an acupuncture needle with bio‐compatible extraction sorbents in the recessed section is developed. The coating material using self‐wettable particles doesn't require solvent activation after sterilization. This device is applied for the anti‐cancer drug concentration monitoring during the in vivo lung perfusion ...
Runshan Will Jiang, Wei Zhou, Marcelo Cypel, Todd L. Demmy, Gal Shafirstein, Guillermo Garza, Emily Gawrys, Joanna Bogusiewicz, Barbara Bojko, Janusz Pawliszyn   +9 more
wiley   +1 more source

Effects of Cannabidiol Oil on Anesthetic Requirements in Cats: MAC Determination and Serum Profiling via Nanoscale Liquid Chromatography-Tandem Mass Spectrometry. [PDF]

Animals (Basel)
Suriyawongpongsa P, Niyom S, Wanapinit K, Vijarnsorn M, Roytrakul S, Ploypetch S.   +5 more
europepmc   +1 more source

Respiratory Sinus Arrhythmia during Recovery from Isoflurane???Nitrous Oxide Anesthesia

, 1985
Yoel Donchin, James M. Feld, Stephen W. Porges   +2 more
openalex   +1 more source