Results 291 to 300 of about 228,231 (339)

Protocol for recording neuronal activity in food and cocaine self-administration in freely behaving mice using calcium imaging. [PDF]

STAR Protoc
Wang J, Wang B, Wang MW, Beacher NJ, Lin DT, Zhang Y.   +5 more
europepmc   +1 more source

Glycolytic Enzyme HK2 Phosphorylates nSMase1 to Promote Astrocytic Exosomes Biogenesis Contributing to Acute Ischemic Stroke Injury

Advanced Science, EarlyView.
This study reveals that the glycolytic enzyme HK2 mediates hypoxia‐induced astrocytic exosome biogenesis by directly phosphorylating nSMase1. These astrocytic exosomes impair brain endothelial tight junctions. Astrocyte‐specific knockdown of HK2 reduces exosome release and alleviates brain injury after MCAO.
Chen Chen, YuWei Zhou, LongXiang Sheng, FangYing Mai, YuXuan Ding, ShiRan Hong, JiaXin Wu, JiaKai Pi, GuangMei Yan, YiJun Huang, JingJing Duan, Xuefeng Hua, Wei Yin   +12 more
wiley   +1 more source

Activation of Kir4.1 Channels by 2‐D08 Promotes Myelin Repair in Multiple Sclerosis

Advanced Science, EarlyView.
Multiple sclerosis causes myelin loss and neurological dysfunction. This study shows that 2‐D08, a small molecule targeting Kir4.1 channels, promotes OPCs differentiation via FYN tyrosine kinase phosphorylation and the FYN/MYRF pathway. It significantly improves myelin repair and motor deficits in EAE mice and marmosets, highlighting its potential as a
Mingdong Liu, Shengyu Jin, Xin Fu, Chong Xie, Yi Chen, Liangtang Chang, Yongheng Fan, Donghua He, Xiaoqi Hong, Xi Shen, Xiaoli Zheng, Qiyue Wang, Dao Shi, Fangyuan Li, Daishun Ling, Yangtai Guan, Neng Gong, Xiaoping Tong   +17 more
wiley   +1 more source

Neonatal sevoflurane anesthesia can also affect rat medulla spinalis. [PDF]

Asian Biomed (Res Rev News)
Ocmen E, Erdost HA, Yilmaz O, Bagriyanik A, Kiray M, Gokmen N.   +5 more
europepmc   +1 more source

Selection of anesthetic agents for obstructive jaundice: An update for anesthesiologists. [PDF]

Medicine (Baltimore)
Li YQ, Zhou X, Cao Y, Long Y.
europepmc   +1 more source

Perioperative analgesic efficacy of quadratus lumborum block versus transversus abdominis plane block in dogs undergoing laparoscopic ovariectomy: a prospective randomized clinical trial. [PDF]

Front Vet Sci
Fumanelli E, Cocca G, Giannetti G, Parabella M, Rabozzi R, Sarotti D.   +5 more
europepmc   +1 more source

Synchronicity of pyramidal neurones in the neocortex dominates isoflurane-induced burst suppression in mice. [PDF]

Br J Anaesth
Yin M, Wang R, Cai Z, Liang Y, Mai F, Wu K, Kong D, Tang P, Pan Y, Ji X, Li F, Liang F, Zhang HF.   +12 more
europepmc   +1 more source

Awake brain MRSI reveals anesthetic sensitivity and regional aging effects on [¹³C]bicarbonate metabolism in mice. [PDF]

Front Neuroimaging
Ono M, Kono R, Hirata K, Saito K, Nakao M, Takakusagi Y, Araki R, Sumiyoshi A, Takado Y.   +8 more
europepmc   +1 more source

In Vitro/In Vivo Evaluation of a Portable Anesthesia Machine with an Oxygen Concentrator for Dogs Under General Anesthesia with Isoflurane. [PDF]

Animals (Basel)
Lee J, Shin D, Sung T, Kim M, Nam C, Son W, Lee I.   +6 more
europepmc   +1 more source