Results 291 to 300 of about 309,332 (398)

Minimally-Invasive Imaging of Sublingual Vessels-A New Method to Study Microvascular Changes in Mice. [PDF]

Life (Basel)
Dyminski Parente Ribeiro E, Dastan M, Bellut-Staeck U, Zhou J, Lehmann C.   +4 more
europepmc   +1 more source

The Minimum Anesthetic Concentration of Isoflurane in Children

, 1984
Calvin B. Cameron, Scott K. Robinson, George A. Gregory   +2 more
openalex   +1 more source

Isoflurane induces dose‐dependent alterations in the cortical connectivity profiles and dynamic properties of the brain's functional architecture

Human Brain Mapping, 2014
R. Hutchison, Melina Hutchison, Kathryn Y. Manning, Ravi S. Menon, S. Everling   +4 more
semanticscholar   +1 more source

Histone Lactylation‐Driven Upregulation of VRK1 Expression Promotes Stemness and Proliferation of Glioma Stem Cells

Advanced Science, EarlyView.
Glioblastoma (GBM) is the most aggressive primary brain tumor, with glioma stem cells (GSCs) driving treatment resistance. This study reveals that lactate promotes histone lactylation (H3K18la) at the VRK1 promoter, regulating GSC stemness and proliferation via the H3K18la/VRK1/YBX1/SOX2 pathway. The VRK1‐targeted nanoliposome A/TMZ‐siVRK1 demonstrates
Jinna Li, Chenyue Tang, Xuefeng Zhang, Rui Xing, Qing Guo   +4 more
wiley   +1 more source

Enhanced Fear Memory in Adult Male C57BL/6 Mice Following Low-Dose Isoflurane Exposure During Juvenile Development. [PDF]

Brain Behav
Sun J, Tang Y, Chang J, Lin J, Luo L, Li Y, Wu G, Hu Y, Zheng Z, Zhang Y.   +9 more
europepmc   +1 more source

Pharmacological Microglial Inhibition Remodels the Scar Microenvironment to Support Reticulospinal Circuit Reconstruction After Spinal Cord Injury

Advanced Science, EarlyView.
This study establishes pharmacological microglial inhibition as a therapeutic strategy, demonstrating its capacity to remodel the lesion microenvironment through significant reduction of extracellular matrix deposition. This permissive environmental transformation facilitates robust regeneration of the reticulospinal tract, and reconstructs functional ...
Run Li, Hongyuan Xing, Yifan Shen, Meng Chen, Bowen Lyu, Xiaofeng Yang, Li Sun, Chao Jiang, Jianyu Lv, Xin Ding, Zhongyang Gao, Yue Wang   +11 more
wiley   +1 more source

Adamts1 Exacerbates Post‐Myocardial Infarction Scar Formation via Mechanosensing of Integrin α8

Advanced Science, EarlyView.
Proposed mechanistic model of ADAMTS1‐ITGα8 mechanotransduction in post‐MI scar formation. Schematic illustration showing the mechanistic pathway by which endothelial cell (EC) derived Adamts1 regulates cardiac fibroblast activation through ITGα8‐mediated mechanotransduction following myocardial infarction (MI).
Chun‐Yan Kong, Zhen Guo, Yu‐Lan Ma, Ming‐Yu Wang, Hai‐Yang Ni, Pan Wang, Wen‐Jun Qiu, En‐Gui Wang, Zhou Li, Zheng Yang, Bo Shen, Qi‐Zhu Tang   +11 more
wiley   +1 more source

Time Required for Extubation While Using Bispectral Index Monitoring Compared to End-Tidal Anesthetic Gas Concentration in Patients Undergoing General Anesthesia. [PDF]

Cureus
Sk A, Kadlimatti DV, Kumar S, Divya PS, Ajith M.   +4 more
europepmc   +1 more source

Nanographene Oxide Attenuates Acute GVHD by Modulating Macrophage Polarization in a Xenogeneic Mouse Model

Advanced Science, EarlyView.
Nanographene oxide (NGO) attenuates graft‐versus‐host disease (GVHD) severity by inhibiting STAT1‐mediated M1 macrophage polarization and suppressing T‐cell activation. NGO‐primed macrophages (NGO‐Mac) further enhance regulatory T‐cell induction via IL‐10. Both NGO and NGO‐Mac therapies mitigate inflammation and immune pathology, offering cell‐free and
Aaron Yu, Hyun Sung Park, Dong‐Hoon Chae, Jae Han Park, Jiyoung Heo, Keonwoo Cho, Jiho Kim, Hyewon Lee, Sueyeon Jee, Chanwoo Kim, Soon Won Choi, Jaechul Ryu, Eun‐Hye Hur, Yunsuk Choi, Eun‐Ji Choi, Mi‐Kyung Oh, Hwa‐Yong Lee, Je‐Hwan Lee, Kyung‐Rok Yu   +18 more
wiley   +1 more source

Comparison of outcomes between total intravenous (propofol and remifentanil) and inhalation (isoflurane) anesthesia in women undergoing abdominal myomectomy: a randomized controlled trial. [PDF]

BMC Anesthesiol
Pouya K, Vejdani R, Taheri M, Marandi PH, Aliyar F, Hakimi P, Azizi H.   +6 more
europepmc   +1 more source