Results 311 to 320 of about 309,332 (398)

LPS‐Induced Mitochondrial Damage via SLC41A1‐Mediated Magnesium Ion Efflux Leads to the Pyroptosis of Dental Stem Cells

Advanced Science, EarlyView.
Lipopolysaccharide induces upregulation of the magnesium (Mg2+) efflux transporter solute carrier family 41 member 1 in dental stem cells, leading to a decrease in intracellular Mg2+ concentration and promoting the binding of oligomycin sensitivity‐conferring protein and cyclophilinD.
Yuan Liu, Chenyu Song, Liyuan Zhang, Xue Han, Chaoyuan Li, Yanhong Yan, Ludan Xing, Mengting Si, Bo Yang, Lingyuan Cheng, Akimi Muramatsu, Beizhan Jiang   +11 more
wiley   +1 more source

Nephrotoxicity and Modern Volatile Anesthetics: A Narrative Review. [PDF]

Toxics
Hauquiert B, Gonze A, Gennart T, Perriens E, Blackman S, De Lissnyder N, Robert A, Moury J, Nendumba G, Oueslati I, Gillis P, Vornicu O, Dincq AS, Bulpa P, Michaux I, Honore PM.   +15 more
europepmc   +1 more source

HMGB2 Promotes Cardiomyocyte Proliferation and Heart Regeneration Through MTA2‐Driven Metabolic Reprogramming

Advanced Science, EarlyView.
In contrast to the adult mammalian heart, which lacks regenerative capacity, the neonatal heart retains a transient regenerative capacity. In this study, high mobility group box 2 (HMGB2) is identified as a crucial protein driving heart regeneration based on comprehensive analyses using quantitative proteomics with tandem mass tag (TMT) labelling, RNA ...
Liu‐Hua Zhou, Ling‐Feng Gu, Yi‐Xi Chen, Peng Jing, Tong‐Tong Yang, Ye He, Yu‐Lin Bao, Xiang‐Zheng Zhang, Chong Du, Si‐Bo Wang, Tian‐Kai Shan, Jia‐Yi Chen, Hao Wang, Qi‐Ming Wang, Li‐Ping Xie, Yang Zhao, Yong Ji, Lian‐Sheng Wang   +17 more
wiley   +1 more source

Vasomotion delineates cerebral vascular dynamic features and participates in the homeostatic cerebral blood flow regulation. [PDF]

Sci Rep
Zhang YY, Li JZ, Wang WT, Xie HQ, Ruan JY, Jia JM.   +5 more
europepmc   +1 more source

Nanocatalytic Neuroprotection and Neurological Recovery Post‐Traumatic Brain Injury

Advanced Science, EarlyView.
This study demonstrates that combining Ce0.7Zr0.3O2 nanozymes with nimodipine enhances neuroprotection after traumatic brain injury. The therapy reduces oxidative stress, neuronal apoptosis, and improves blood–brain barrier integrity, with nanozymes effective at low doses.
Xinjie Hong, Liang Zhao, Xianzheng Sang, Chao Ma, Meiqi Chang, Xinran Song, Wei Feng, Tao Xu, Li Ding, Yu Chen, Lijun Hou   +10 more
wiley   +1 more source

N-Acety-L-Cysteine Alleviates Isoflurane-Triggered Neuronal Cell Parthanatos by Suppressing Reactive Oxygen Species Accumulation Through the Induction of c-Jun N-Terminal Kinase Signaling Pathway Inhibition. [PDF]

J Biochem Mol Toxicol
Liu N, Liu Y, Wang X, Liu M, Wang Y, Feng C, Piao M.   +6 more
europepmc   +1 more source

Engineering Neutrophil Vesicles for Synergistic Protection against Ischemia/Reperfusion Injury after Lung Transplant

Advanced Science, EarlyView.
Engineered neutrophil‐derived vesicles (SOD2‐Fer‐1@CVs) co‐delivering antioxidant and ferroptosis‐inhibitory agents enable inflammation‐targeted, ROS‐responsive therapy for ischemia–reperfusion injury in lung transplantation. Synergizing with ex vivo lung perfusion, this strategy alleviates oxidative stress and inflammation, restores vascular integrity,
Hao‐Xiang Yuan, Yu‐Yun Ye, Pu Shen, Jie Zhang, Qian‐Fang Meng, Ying Chen, Xin Xu, Xuan‐Lin Zhang, Lang Rao, Zhi‐Jin Fan, Jian‐Xing He   +10 more
wiley   +1 more source

Comparison of the Effects of Isoflurane and Propofol as Anesthesia Maintenance on Plasma Mitochondrial DNA Levels in Posterior Spinal Fusion Surgeries. [PDF]

Anesth Pain Med
Behnaz F, Erfanian M, Chegini A.
europepmc   +1 more source

Lesion to left hippocampus changes functional connectivity according to changes in structure [PDF]

, 2014
Descamps, Benedicte, Fias, Wim, Marinazzo, Daniele, Raedt, Robrecht, Siugzdaite, Roma, Van Den Berge, Nathalie, van Mierlo, Pieter, Wu, G   +7 more
core