Results 101 to 110 of about 9,712,779 (339)
Extremal Isolated Horizon/CFT Correspondence
The near-horizon limit of the extremal (weakly) isolated horizon is obtained under the Bondi-like coordinates. For the vacuum case, explicit coordinate transformation relating the near-horizon metric under the Bondi-like coordinates and the standard ...
A. Ashtekar +3 more
core +1 more source
Heterogeneous Isolated Execution for Commodity GPUs
Traditional CPUs and cloud systems based on them have embraced the hardware-based trusted execution environments to securely isolate computation from malicious OS or hardware attacks.
Insu Jang +4 more
semanticscholar +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Introduction: Chronic household food insecurity (HFI) and lack of food availability and accessibility in isolated communities are longstanding public health crises.
Mallory Drysdale +5 more
doaj +1 more source
High-order 3D Voronoi tessellation for identifying Isolated galaxies, Pairs and Triplets
Geometric method based on the high-order 3D Voronoi tessellation is proposed for identifying the single galaxies, pairs and triplets. This approach allows to select small galaxy groups and isolated galaxies in different environment and find the isolated ...
A. Elyiv +75 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
The newfound relationship between extrachromosomal DNAs and excised signal circles
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Intellectualism is the widespread view that practical reason is a species of theoretical reason, distinguished from others by its objects: reasons to act. I argue that if practical reason is a species of theoretical reason, practical judgments by nature have nothing to do with action.
openaire +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source

