Results 51 to 60 of about 1,922,635 (306)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Design and Optimization of an Efficient (96.1%) and Compact (2 kW/dm3) Bidirectional Isolated Single-Phase Dual Active Bridge AC-DC Converter

Energies, 2016
The growing attention on plug-in electric vehicles, and the associated high-performance demands, have initiated a development trend towards highly efficient and compact on-board battery chargers.
Jordi Everts
doaj   +1 more source

Design and analysis of a novel coupled converter with high‐voltage insulation protection in magnetic isolated way

IET Power Electronics, 2021
This paper presents a novel coupled converter with high‐voltage insulation protection in magnetic isolated way by taking the case of heater/ignitor/keeper supply for powering discharge cathode in the space ion electric propulsion (EP) thruster.
Ming Fu, Donglai Zhang, Di Zhang, Xiantao Zhang   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

An Analysis-Supported Design of a Single Active Bridge (SAB) Converter

Energies, 2022
Currently, due to its various applications, the high-performance isolated dc-dc converter is in demand. In applications where unidirectional power transfer is required, the single active bridge (SAB) is the most suitable one due to its simplicity and ...
Rupesh Jha, Mattia Forato, Satya Prakash, Hemant Dashora, Giuseppe Buja   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Solid-State Transformers: A Review—Part II: Modularity and Applications

Technologies
The Solid-State Transformer (SST) is a complex conversion device that intends to replace the Low-Frequency Transformers (LFTs) used in various power applications with Medium- or High-Frequency Transformers (MFTs/HFTs) that integrate modular converter ...
Dragoș-Mihail Predescu, Ștefan-George Roșu   +1 more
doaj   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

FEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil, Jeffrey A. Hawkes, Cecilia Blikstad, Pia Lindberg   +3 more
wiley   +1 more source

An Interleaved Current-Fed PFC Flyback Converter With Voltage Follower Characteristic

IEEE Open Journal of Power Electronics
This article proposes an interleaved modified flyback converter employing pulse frequency modulation (PFM) for power factor correction (PFC) applications. The topology integrates a switching cell (SC) and coupled inductors, enabling soft commutation over
Edwin Augusto Tonolo, Jefferson Wilhelm Meyer Soares, Alceu Andre Badin   +2 more
doaj   +1 more source

Artificial molecular machines and motors—Design and control of nanoscale motion

FEBS Letters, EarlyView.
Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley   +1 more source