Results 251 to 260 of about 53,308 (359)

β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations

Advanced Biology, Volume 9, Issue 3, March 2025.
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio, B. Spedicato, G. Corallo, A. Inguscio, M. Greco, D. Musarò, D. Vergara, A. F. Muro, G. De Sabbata, L. R. Soria, N. Brunetti Pierri, M. Maffia   +11 more
wiley   +1 more source

Progression to rheumatoid arthritis in at-risk individuals is defined by systemic inflammation and by T and B cell dysregulation. [PDF]

Sci Transl Med
He Z, Glass MC, Venkatesan P, Feser ML, Lazaro L, Okada LY, Tran NTT, He YD, Zaim SR, Bennett CE, Ravisankar P, Dornisch EM, Ferrannini AC, Arishi NA, Asamoah AG, Barzideh S, Becker LA, Bemis EA, Buckner JH, Collora CE, Criley MAL, Demoruelle MK, Fleischer CL, Garber J, Genge PC, Gong Q, Graybuck LT, Gustafson CE, Hattel BC, Hernandez V, Heubeck AT, Kawelo EK, Krishnan U, Kuan EL, Kuhn KA, LaFrance CM, Lee KJ, Li R, Lord C, Mettey RR, Moss L, Musgrove B, Nguyen KH, Ochoa A, Parthasarathy V, Pebworth MP, Pedrick C, Peng T, Phalen CG, Reading J, Roll CR, Seifert JA, Siedschlag MD, Speake C, Striebich CC, Stuckey TJ, Swanson EG, Takada H, Thai T, Thomson ZJ, Trieu N, Tsaltskan V, Wang W, Weiss MDA, Westermann A, Zhang F, Boyle DL, Goldrath AW, Bumol TF, Li XJ, Holers VM, Skene PJ, Savage AK, Firestein GS, Deane KD, Torgerson TR, Gillespie MA.   +76 more
europepmc   +1 more source

CASCADED Z-SOURCE ISOLATED DC-DC CONVERTER WITH PWM SHOOT THROUGH CONTROL METHODS

, 2019
Nimrah Saeed, Anas Ibrar, Huma Hafeez, Lubna Majeed   +3 more
openalex   +1 more source

Understanding the Effect of Resistance Temperature Detector Temperature Controllers on Microstructural Alignment in Magnetic Freeze Casting

Advanced Engineering Materials, EarlyView.
The effect of temperature controllers that are commonly used in freeze‐casting is investigated in this work. Temperature controllers are observed to generate a voltage in the slurry. Microstructural alignment and ultimate compressive strength data show this voltage to interfere with the ability to align the microstructure using magnetic fields ...
Maddie A. Schmitz, Steven E. Naleway
wiley   +1 more source

A comparative analysis of supraharmonic emission by DC fast chargers used for electric vehicle charging. [PDF]

Sci Rep
Rajkumar S, Balasubramanian R, Kathirvelu KP.   +2 more
europepmc   +1 more source

Evaluation of the Potential of Laser Shock Peening Compared with Cold Expansion for Improving Fatigue Resistance of Riveted Lap Joints of Aerospace Grade 7175 Al Alloy

Advanced Engineering Materials, EarlyView.
This study investigates laser shock peening for enhancing fatigue performance of riveted aerospace aluminum joints. A comparative approach with cold expansion combines fatigue testing and synchrotron X‐ray methods. Integrating mechanical testing with residual stress and strain characterization provides insights into how different treatments affect the ...
Ogün Baris Tapar, David Osman Busse, Maximilian Sprengel, Domenico Furfari, Marc‐André Nielsen, Guilherme Abreu Faria, Jérémy Epp   +6 more
wiley   +1 more source

Altered network efficiency in isolated REM sleep behavior disorder: A multicentric study. [PDF]

Alzheimers Dement
Tremblay C, Pastor-Bernier A, Rheault F, Daneault V, Ayral V, Filiatrault M, Desaulniers L, Vo A, Gagnon JF, Postuma RB, Dusek P, Marecek S, Varga Z, Klein JC, Hu MT, Lehéricy S, Arnulf I, Dodet P, Vidailhet M, Corvol JC, ICEBERG Study Group, Rahayel S.   +21 more
europepmc   +1 more source

Enabling Digital Continuity in Virtual Manufacturing for Eco‐Efficiency Assessment of Lightweight Structures by Means of a Domain‐Specific Structural Mechanics Language: Requirements, Idea and Proof of Concept

Advanced Engineering Materials, EarlyView.
This article presents a solver‐agnostic domain‐specific language (DSL) for computational structural mechanics that strengthens interoperability in virtual product development. Using a hierarchical data model, the DSL enables seamless exchange between diverse simulation tools and numerical methods.
Martin Rädel, Andreas Schuster, Felix Schoenitz, Jean Lefèvre   +3 more
wiley   +1 more source

Association of DTI-ALPS Glymphatic Index With Differential Phenoconversion in Isolated REM Sleep Behavior Disorder: A Multi-Cohort MRI Study. [PDF]

Neurology
Ayral V, Pastor-Bernier A, Daneault V, Tremblay C, Filiatrault M, Haddad C, Gagnon JF, Postuma RB, Dušek P, Marecek S, Varga Z, Klein JC, Hu MT, Lehéricy S, Arnulf I, Vidailhet M, Corvol JC, ICEBERG Study Group, Rahayel S.   +18 more
europepmc   +1 more source

Efficient Process Development for Laser Powder Bed Fusion of a Soft‐Magnetic Metallic Glass Composite

Advanced Engineering Materials, EarlyView.
Iron‐based metallic glass alloys exhibit excellent soft‐magnetic properties, and unprecedented geometrical freedom in the design of soft‐magnetic metallic glass components is made possible by additive manufacturing. An efficient workflow for developing parameters for laser‐based powder bed fusion of a Fe‐based metallic glass alloy is presented along ...
Julia Löfstrand, Priyanka Saha, Vidhiaza Leviandhika, Urban Wiklund, Alexander Elsen, Carolin Zintel, Lena Thorsson, Petra E. Jönsson   +7 more
wiley   +1 more source