Results 111 to 120 of about 42,511 (255)
British Journal of Pharmacology, EarlyView.Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu +4 more
wiley +1 more source
PLoS ONE, 2014 Recent repeated isolation of H14 hemagglutinin subtype influenza A viruses (IAVs) in the New World waterfowl provides evidence to suggest that host and/or geographic ranges for viruses of this subtype may be expanding.
Andrew M Ramey +5 more
doaj +1 more source
Zinc Uptake by Isolated Rat Enterocytes: Effect of Low Molecular Weight Ligands
Experimental Biology and Medicine, 1989 The luminal phase of zinc intestinal absorption has not been well characterized. This study was intended to elucidate the possible role of low molecular weight (LMW) ligands in zinc intestinal transport in an isolated rat enterocyte system. Under these in vitro conditions, zinc uptake by the isolated enterocytes was rapid, leveling off within 1 min ...
R D, Raffaniello, R A, Wapnir
openaire +2 more sources
Cancer Science, EarlyView.Colorectal cancer (CRC) shows high molecular heterogeneity, yet single‐cell data from Japanese patients are limited. We performed scRNA‐seq on tumors and adjacent normal tissues from four Japanese CRC patients and identified a shared malignant cell cluster with high KCNQ1OT1 expression and reduced RASSF6 levels.
Sadahiro Iwabuchi +15 more
wiley +1 more source
Altered gene expression in highly purified enterocytes from patients with active coeliac disease
BMC Genomics, 2008 Background Coeliac disease is a multifactorial inflammatory disorder of the intestine caused by ingestion of gluten in genetically susceptible individuals.
Jackson John +4 more
doaj +1 more source
Human Apolipoprotein B Transgenic Mice Generated with 207- and 145-Kilobase Pair Bacterial Artificial Chromosomes. Evidence that a distant 5'-element confers appropriate transgene expression in the intestine [PDF]
, 1997 We reported previously that ~80-kilobase pair (kb) P1 bacteriophage clones spanning either the human or mouse apoB gene (clones p158 and p649, respectively) confer apoB expression in the liver of transgenic mice, but not in the intestine. We hypothesized
Gunn, Michael D. +6 more
core
Potassium currents of isolated Necturus enterocytes: a whole‐cell patch‐clamp study.
The Journal of Physiology, 1991 1. The whole‐cell recording mode of the patch‐clamp technique was used to investigate the ionic currents of enterocytes isolated from the small intestine epithelium of Necturus maculosus. 2. When enterocytes were bathed in a physiological Ringer solution and dialysed with a K(+)‐rich intracellular solution containing 1.5 x 10(‐7) M intracellular Ca2 ...
D N, Sheppard +3 more
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Diabetes, Obesity and Metabolism, EarlyView.ABSTRACT Aim To investigate whether common disturbances of glucose and lipid metabolism can be automatically identified from magnetic resonance signatures of the pancreas and liver. Methods In this proof‐of‐principle study, 100 individuals with a history of pancreatitis—a relatively homogeneous population at risk for metabolic derangements—underwent ...
Wandia Kimita +5 more
wiley +1 more source
Adhesive factor/rabbit 2, a new fimbrial adhesin and a virulence factor from Escherichia coli O103, a serogroup enteropathogenic for rabbits [PDF]
, 1997 Enteropathogenic Escherichia coli-like E. coli strains belonging to serovar O103:K-:H2 and rhamnose-negative biotypes are highly pathogenic diarrhea-inducing strains for weaned European rabbits.
Fiederling, Franck +3 more
core +1 more source
Control of growth and gut maturation by HoxD genes and the associated lncRNA Haglr. [PDF]
, 2017 During embryonic development, Hox genes participate in the building of a functional digestive system in metazoans, and genetic conditions involving these genes lead to important, sometimes lethal, growth retardation. Recently, this phenotype was obtained
Darbellay, Fabrice +4 more
core +1 more source