Results 41 to 50 of about 42,511 (255)

Rab8a and Rab8b are essential for several apical transport pathways but insufficient for ciliogenesis [PDF]

, 2013
The small GTP-binding protein Rab8 is known to play an essential role in intracellular transport and cilia formation. We have previously demonstrated that Rab8a is required for localising apical markers in various organisms.
A. Harada, H. Hagiwara, M. Kunii, M. Yuzaki, R. Harada, R. Mizuguchi, S. Matsuda, T. Iwano, T. Sato, Y. Jung, Y. Yoshihara   +10 more
core   +2 more sources

Progressive Morphogenesis IN VIVO after Transplantation of Cultured Small Bowel Epithelium

Cell Transplantation, 1994
An experimental model for the primary culture and transplantation of late foetal rat small intestinal epithelium is described. Multicellular aggregates of mucosal epithelium containing pre-crypt proliferative cells were isolated from 20-day foetal rat ...
I.S. Tait, G.S. Evans, M. Kedinger, N. Flint, C.S. Potten, F.C. Campbell MD FRCS   +5 more
doaj   +1 more source

Dynamic interactions of a conserved enterotoxigenic Escherichia coli adhesin with intestinal mucins govern epithelium engagement and toxin delivery [PDF]

, 2016
At present, there is no vaccine for enterotoxigenic Escherichia coli (ETEC), an important cause of diarrheal illness. Nevertheless, recent microbial pathogenesis studies have identified a number of molecules produced by ETEC that contribute to its ...
Bhullar, Kirandeep, Fleckenstein, James M, Kuhlmann, F. Matthew, Kumar, Pardeep, Luo, Qingwei, Vallance, Bruce A, Xia, Lijun, Yang, Hyungjun   +7 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Molecular transport through primary human small intestinal monolayers by culture on a collagen scaffold with a gradient of chemical cross-linking

Journal of Biological Engineering, 2019
Background The luminal surface of the small intestine is composed of a monolayer of cells overlying a lamina propria comprised of extracellular matrix (ECM) proteins.
Jennifer E. Speer, Dulan B. Gunasekara, Yuli Wang, John K. Fallon, Peter J. Attayek, Philip C. Smith, Christopher E. Sims, Nancy L. Allbritton   +7 more
doaj   +1 more source

Ligilactobacillus salivarius 7247 Strain: Probiotic Properties and Anti-Salmonella Effect with Prebiotics

Antibiotics, 2023
The Ligilactobacillus salivarius 7247 (LS7247) strain, originally isolated from a healthy woman’s intestines and reproductive system, has been studied for its probiotic potential, particularly against Salmonella Enteritidis (SE) and Salmonella ...
Vyacheslav M. Abramov, Igor V. Kosarev, Andrey V. Machulin, Evgenia I. Deryusheva, Tatiana V. Priputnevich, Alexander N. Panin, Irina O. Chikileva, Tatiana N. Abashina, Ashot M. Manoyan, Anna A. Ahmetzyanova, Olga E. Ivanova, Tigran T. Papazyan, Ilia N. Nikonov, Nataliya E. Suzina, Vyacheslav G. Melnikov, Valentin S. Khlebnikov, Vadim K. Sakulin, Vladimir A. Samoilenko, Alexey B. Gordeev, Gennady T. Sukhikh, Vladimir N. Uversky   +20 more
doaj   +1 more source

Lactic acid bacteria isolated from poultry protect the intestinal epithelial cells of chickens from in vitro wheat germ agglutinin-induced cytotoxicity [PDF]

, 2018
Poultry fed on wheat-based diets regularly ingest wheat germ agglutinin (WGA) that has toxic effects in vitro on intestinal epithelial cells (IEC) obtained from 14-d-old broilers.
Apella, Maria Cristina, Argañaraz Martínez, Fernando Eloy, Babot, Jaime Daniel, Lorenzo Pisarello, Maria Jose, Perez Chaia, Adriana Beatriz   +4 more
core   +1 more source

Oral Dosed Organo‐Silica Nanoparticles Restore Glucose Homeostasis and β‐Cell Function in Diabetes Rats

Advanced Functional Materials, EarlyView.
An oral nanoplatform, MOP@T@D, which can maintain glucose homeostasis and restore islet β cells in diabetic rats is developed. It achieves efficient intestinal absorption and liver‐targeted delivery. The nanoparticle disintegrates only in response to hyperglycemia to release insulin on demand and provides antioxidant protection through selenoprotein ...
Chenxiao Chu, Mingli Wei, Che Bian, Xiaoshuang Bi, Yaxin Deng, Peifu Xiao, Jiansong Zhao, Yuying Wang, Haibing He, Jingxin Gou, Tian Yin, Xing Tang, Li Yang, Hongbo Zhang, Yu Zhang   +14 more
wiley   +1 more source

Investigation of the influence of high glucose on molecular and genetic responses: an in vitro study using a human intestine model

Genes & Nutrition, 2018
Background Dietary glucose consumption has increased worldwide. Long-term high glucose intake contributes to the development of obesity and type 2 diabetes mellitus (T2DM). Obese people tend to eat glucose-containing foods, which can lead to an addiction
Tugce Boztepe, Sukru Gulec
doaj   +1 more source

Characterization of the proteome of cytoplasmic lipid droplets in mouse enterocytes after a dietary fat challenge. [PDF]

PLoS ONE, 2015
Dietary fat absorption by the small intestine is a multistep process that regulates the uptake and delivery of essential nutrients and energy. One step of this process is the temporary storage of dietary fat in cytoplasmic lipid droplets (CLDs).
Theresa D'Aquila, Devika Sirohi, Jeffrey M Grabowski, Victoria E Hedrick, Lake N Paul, Andrew S Greenberg, Richard J Kuhn, Kimberly K Buhman   +7 more
doaj   +1 more source