Results 71 to 80 of about 64,140 (250)

Sex Differences in the Association of Simultaneous Decline in Blood Pressure and Decline in Cognition during Aging

Annals of Neurology, EarlyView.
Objective Both high and declining blood pressure (BP) are associated with risk of cognitive decline in older adults, and women have higher rates of hypertension and faster cognitive decline in late‐life. In old age, the relationship between changes in BP and changes in cognition is complex, and although sex differences in cognitive function and decline
Nicholas W. Baumgartner, Ana W. Capuano, Lisa L. Barnes, David A. Bennett, Zoe Arvanitakis   +4 more
wiley   +1 more source

Diabetes and the Metabolic Syndrome as Drivers of Neurodegeneration: Convergent Mechanisms Linking Peripheral Neuropathy and Dementia

Annals of Neurology, EarlyView.
The metabolic syndrome, a state of progressive metabolic dysfunction, injures the peripheral and central nervous systems, promoting peripheral neuropathy (PN) and cognitive impairment (CI), respectively. We posit PN and CI are connected in the metabolic syndrome framework, built on the premise that neurons, whether in the peripheral or central nervous ...
Masha G. Savelieff, David L. Bennett, Troels S. Jensen, Eva L. Feldman   +3 more
wiley   +1 more source

To Know the Prevalence and Risk Factors of Isolated Systolic Hypertension among Adults Aged 30 Years and Above in Davangere Taluka

National Journal of Community Medicine, 2019
Background: The WHO has estimated that globally hypertension is directly responsible for about 62% of cerebrovascular disease and 49% of ischemic heart disease.
Anurupa MS, Rashmi R, Shubha DB
doaj  

Isolated systolic hypertension and the J-curve of cardiovascular disease risk☆

Artery Research, 2010
Controversy persists regarding the presence and significance of blood pressure “J-curves” of increased cardiovascular disease (CVD) risk as they relate to older people with isolated systolic hypertension (ISH).
Stanley S. Franklin
doaj   +1 more source

Candesartan and hydrochlorothiazide in isolated systolic hypertension

Blood Pressure, 2003
We investigated the efficacy and safety of daily candesartan 8/16mg and hydrochlorothiazide 12.5 mg as monotherapy and in combination in older patients with systolic hypertension.The study used a double-blind randomized placebo-controlled crossover design. Treatment phases were of 6 weeks duration.
Wing, Lindon Michael, Upton, J M, Molloy, D A, Arnolda, Leonard F   +3 more
openaire   +3 more sources

A critical reappraisal of the carotid sinus and carotid bulb: Distinguishing neurohistological function from vascular geometry

The Anatomical Record, EarlyView.
This review redefines the carotid bulb (CB) as a variable geometric dilation shaped by hemodynamics and the carotid sinus (CS) as a conserved neurohistological baroreceptor field. Distinguishing these entities clarifies a century of anatomical confusion and links geometry, neurohistology, and clinical interpretation within a unified framework ...
Răzvan Costin Tudose, Nicolae Radu, Mugurel Constantin Rusu   +2 more
wiley   +1 more source

Hypertension Subtypes among Hypertensive Patients in Ibadan

International Journal of Hypertension, 2014
Background. Certain hypertension subtypes have been shown to increase the risk for cardiovascular morbidity and mortality and may be related to specific underlying genetic determinants.
Abiodun M. Adeoye, Adewole Adebiyi, Bamidele O. Tayo, Babatunde L. Salako, Adesola Ogunniyi, Richard S. Cooper   +5 more
doaj   +1 more source

Cytokine Pathways Driving Diverse Tissue Pathologies in Rheumatoid Arthritis

Arthritis &Rheumatology, EarlyView.
Rheumatoid arthritis (RA) is a complex systemic disorder characterized primarily by articular inflammation and destruction with associated functional loss and reduced quality of life. RA is also associated with extra‐articular disease, such as that of the lung, with potentially devastating clinical consequences. The critical importance of comorbidities,
Aurelie Najm, Lyn D. Ferguson, Iain B. McInnes   +2 more
wiley   +1 more source

TWEAK/Fn14 Signaling Drives Oxidative Cardiac Injury in Systemic Lupus Erythematosus: Evidence From Patient Biomarker Studies, Lupus Mouse Models, and Cardiomyocyte Assays

Arthritis &Rheumatology, EarlyView.
Objective Cardiac involvement is a major cause of morbidity in systemic lupus erythematosus (SLE). Tumor necrosis factor–like weak inducer of apoptosis (TWEAK) is elevated in SLE, but its contribution to lupus‐associated cardiac injury is unclear. We investigated the role of TWEAK/fibroblast growth factor–inducible 14 (Fn14) signaling in SLE‐related ...
Yale Liu, Zhu Yan, Xueting Peng, Meixuan Li, Juan Wang, Yan Zhang, Xiaoqian Hu, Mingzhu Zhou, Kaixuan Ren, Dan Zhang, Xingyi Guo, Yumin Xia, Huanhuan Huo   +12 more
wiley   +1 more source

Effect of renal denervation for patients with isolated systolic hypertension: a systematic review and meta-analysis. [PDF]

J Geriatr Cardiol, 2023
Li L, Xiong YL, Tu B, Liu SY, Zhang ZH, Hu Z, Yao Y.   +6 more
europepmc   +1 more source