Results 81 to 90 of about 66,057 (284)

Project Retrosight. Understanding the returns from cardiovascular and stroke research: Case Studies [PDF]

, 2011
Copyright @ 2011 RAND Europe. All rights reserved. The full text article is available via the link below.This project explores the impacts arising from cardiovascular and stroke research funded 15-20 years ago and attempts to draw out aspects of the ...
Pollitt, A, Wooding, S, Hanney, S, Grant, J, Buxton, MJ   +4 more
core  

Identification of phenotypes at risk of transition from diastolic hypertension to isolated systolic hypertension

, 2015
Little is known about the potential progression of hypertensive patients towards isolated systolic hypertension (ISH) and about the phenotypes associated with the development of this condition.
ESPOSITO, GIOVANNI, IZZO, RAFFAELE, STABILE, EUGENIO, DE SIMONE, GIOVANNI, ESPOSITO, roberta, DE LUCA, NICOLA, ROZZA, FRANCESCO, GALDERISI, MAURIZIO, DE MARCO, MARINA, TRIMARCO, VALENTINA   +9 more
core   +1 more source

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

To Know the Prevalence and Risk Factors of Isolated Systolic Hypertension among Adults Aged 30 Years and Above in Davangere Taluka

National Journal of Community Medicine, 2019
Background: The WHO has estimated that globally hypertension is directly responsible for about 62% of cerebrovascular disease and 49% of ischemic heart disease.
Anurupa MS, Rashmi R, Shubha DB
doaj  

Hypertension Subtypes among Hypertensive Patients in Ibadan

International Journal of Hypertension, 2014
Background. Certain hypertension subtypes have been shown to increase the risk for cardiovascular morbidity and mortality and may be related to specific underlying genetic determinants.
Abiodun M. Adeoye, Adewole Adebiyi, Bamidele O. Tayo, Babatunde L. Salako, Adesola Ogunniyi, Richard S. Cooper   +5 more
doaj   +1 more source

Isolated systolic hypertension and the J-curve of cardiovascular disease risk☆

Artery Research, 2010
Controversy persists regarding the presence and significance of blood pressure “J-curves” of increased cardiovascular disease (CVD) risk as they relate to older people with isolated systolic hypertension (ISH).
Stanley S. Franklin
doaj   +1 more source

Candesartan and hydrochlorothiazide in isolated systolic hypertension

Blood Pressure, 2003
We investigated the efficacy and safety of daily candesartan 8/16mg and hydrochlorothiazide 12.5 mg as monotherapy and in combination in older patients with systolic hypertension.The study used a double-blind randomized placebo-controlled crossover design. Treatment phases were of 6 weeks duration.
Wing, Lindon Michael, Upton, J M, Molloy, D A, Arnolda, Leonard F   +3 more
openaire   +3 more sources

Integrated Clinical and Proteomic Profiling of CD19 Chimeric Antigen Receptor T Cell Therapy in Progressive Systemic Sclerosis

Arthritis &Rheumatology, EarlyView.
Objective To characterize the clinical, immunologic, and proteomic changes associated with CD19 chimeric antigen receptor T cell therapy in patients with progressive systemic sclerosis (SSc). Methods Patients with progressive SSc received CD19 chimeric antigen receptor (CAR)‐T cell therapy and were observed longitudinally for safety, clinical efficacy,
Chenhan Jia, Wanyi Lin, Zhangyi Zhao, Fenglin Wu, Chaoyu Gu, Yuankai Sun, Zhe Ding, Chang Wei, Xinyu Li, Cuiwei Xie, Peng Xia, Zhen Xia, Xuesong Liu, Shaoying Yang, Chunyan Zhang, Hanlin Yin, Liangjing Lu   +16 more
wiley   +1 more source

ALK1 controls hepatic vessel formation, angiodiversity, and angiocrine functions in hereditary hemorrhagic telangiectasia of the liver

Hepatology, EarlyView., 2022
Hepatic endothelial Alk1 signaling protects from development of vascular malformations while maintaining organ‐specific endothelial differentiation and angiocrine portmanteau of the names Wingless and Int‐1 signaling. Abstract Background and Aims In hereditary hemorrhagic telangiectasia (HHT), severe liver vascular malformations are associated with ...
Christian David Schmid, Victor Olsavszky, Manuel Reinhart, Vanessa Weyer, Felix A. Trogisch, Carsten Sticht, Manuel Winkler, Sina W. Kürschner, Johannes Hoffmann, Roxana Ola, Theresa Staniczek, Joerg Heineke, Beate K. Straub, Jens Mittler, Kai Schledzewski, Peter ten Dijke, Karsten Richter, Steven Dooley, Cyrill Géraud, Sergij Goerdt, Philipp‐Sebastian Koch   +20 more
wiley   +1 more source

Prevalence, pathophysiology and treatment of isolated systolic hypertension in the elderly

, 2004
Isolated systolic hypertension is the predominant type of hypertension in the elderly and is associated with cardiovascular complications such as stroke, coronary heart disease and heart failure.
Staessen, Jan A., Nawrot, Tim, Thijs, Lutgarde, Den Hond, Elly   +3 more
core   +2 more sources