Results 191 to 200 of about 1,993,131 (236)

Apigenin Protects Hypertensive Intracerebral Hemorrhage by Regulating Trx1 Through Binding to PRDX2

Phytotherapy Research, EarlyView.
ABSTRACT Intracerebral hemorrhage (ICH) remains the most severe stroke subtype with high mortality and disability rates. Although apigenin has shown cerebroprotective potential in preclinical studies, its mechanism of action, particularly in hypertensive ICH, remains poorly understood.
Hao‐chen Xu, Ming Liu, Ying‐ying Sun, Jie‐Dan Ping, Qing‐hua Cui, Jing‐zhou Chen, Hao Li   +6 more
wiley   +1 more source

Echocardiographic assessment of pulmonary hypertension: a hierarchical interpretive framework for clinical decision-making and echo laboratory practice. [PDF]

Echo Res Pract
Shrivastav A, Tivaskar S, Luharia A, Gomase S, Lanjewar R.   +4 more
europepmc   +1 more source

Determinants of preterm pre‐eclampsia following low‐dose aspirin prophylaxis: evidence from stepped‐wedge cluster randomized trial in Asia

Ultrasound in Obstetrics &Gynecology, EarlyView.
ABSTRACT Objectives To identify potential risk factors – among maternal factors, pre‐eclampsia (PE)‐specific biomarkers and estimated risks derived from the first‐trimester Fetal Medicine Foundation (FMF) triple test – that are associated with the subsequent development of preterm PE, and to evaluate predictors of any‐onset PE using time‐to‐event ...
J. Lin, L. Nguyen‐Hoang, L. T. Dinh, R. K. Pooh, A. Ohkuchi, M. Zheng, Y. Wu, A. Kusuma, T. Wataganara, M. Choolani, M. Kaneko, S. Luewan, T.‐Y. Chang, N. Chaiyasit, T. Nanthakomon, H. Liu, S. W. Shaw, L. C. Poon, FORECAST collaborators, I. S. Wong, J. S. Y. Wong, Y. Chen, J. Liu, X. Wang, S. Moungmaithong, X. Lu, L. Wong, F. Liu, A. W. T. Tse, H. H. Y. Leung, N. M. W. Lee, S. L. Lau, I. Y. M. Wah, D. S. Sahota, M. K. C. Chong, D.‐A. Nguyen, A. Shiozaki, Y. Hu, R. Ma, B. Li, Y. M. Jiang, A. Gosavi, A. Sekizawa, W. C. Leung, Z. A. Mahdy, A. Aguilar, O. Shimokawa   +46 more
wiley   +1 more source

Isolated Diastolic Hypertension and Cardiovascular Disease Risk in Young Adults. [PDF]

Hypertension
Tang R, An J, Moran AE, Shimbo D, Allen NB, Xanthakis V, Reynolds K, Zhang Y.   +7 more
europepmc   +1 more source

Integrative proteomic profiling of extracellular vesicle‐enriched preparations with machine learning identifies disease activity‐associated signatures linked to adverse pregnancy outcomes in systemic lupus erythematosus

VIEW, EarlyView.
Integrating cross‐cohort extracellular vesicle proteomics with machine learning identifies a simplified protein signature (AGT, FETUB, SPP2, and FCN3) for adverse pregnancy outcome risk stratification in systemic lupus erythematosus, enabling precise disease‐activity discrimination beyond routine clinical assessment.
Weiwei Shi, Xipei Huang, Wutao Chen, Wen Di, Lin Huang, You Wang   +5 more
wiley   +1 more source

Chronic Disease and Disability in the United States: Trends, Inequities, and Imperatives for Policy Reform

The Milbank Quarterly, EarlyView.
Policy Points Position Universal, High‐Quality Education as a Foundational Public Health Strategy. Long‐term health and life expectancy in the United States are shaped more by educational attainment than by any other single factor. Disparities in access to early childhood, K‐12, and higher education perpetuate cycles of chronic disease, economic ...
ALI H. MOKDAD, LAURA DWYER‐LINDGREN, CHRISTOPHER J.L. MURRAY   +2 more
wiley   +1 more source

Distinct Urinary Protein Signatures in Adolescent Blood Pressure Phenotypes. [PDF]

Circ Res
Thürmann L, Seegebarth A, von Berg A, Berdel D, Koletzko S, Heinrich J, Schikowski T, Lehmann I, Standl M, Trump S.   +9 more
europepmc   +1 more source

Hormone Replacement Therapy for Menopausal Symptoms and the Risk of Cardiometabolic Disease: Current Evidence and Future Directions

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Background The transition through menopause is accompanied by a series of adverse metabolic changes which are associated with an increased risk of cardiometabolic disease, a major cause of mortality in women after midlife. Whilst the indication for menopausal hormone replacement therapy (HRT) is the control of menopausal symptoms ...
Jiawen Dong, Sarah Hillman, Sharon Dixon, Anupa Shah, Radha Venkatakrishnan, Jeremy W. Tomlinson   +5 more
wiley   +1 more source

The Silent Threat: Unmasking Combined Post- and Pre-capillary Pulmonary Hypertension (CpcPH) in an Elderly Patient With Heart Failure With Preserved Ejection Fraction (HFpEF). [PDF]

Cureus
Bhatt PR, Gupta A, Ray A, Sharma A, Raza S, Kammaripalle T, Bhandari M.   +6 more
europepmc   +1 more source

Association Between Proteinuria and Pregnancy Outcomes in Women With Preterm Pre‐Eclampsia Undergoing Expectant Management: Secondary Analysis of Two Randomised Trials

BJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT Objective Evaluate whether proteinuria levels, in women undergoing expectant management for pre‐eclampsia, are associated with pregnancy latency and adverse outcomes. Design Secondary analysis of data from two randomised trials. Setting Tygerberg Hospital, Cape Town, South Africa.
Amy van Rooyen, Lina Bergman, Henrik Imberg, Denise Sproul, Susan P. Walker, Stephen Tong, Catherine A. Cluver   +6 more
wiley   +1 more source