Results 41 to 50 of about 1,993,131 (236)

The benefit of treating isolated systolic hypertension [PDF]

, 2001
Isolated systolic hypertension affects over 15% of all people older than 60 years of age. In the elderly, systolic hypertension is a major modifiable cardiovascular risk factor. Systolic blood pressure is associated with higher risk of an adverse outcome.
Staessen, Jan A., Wang, J.G.
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Prognostic significance of serum creatinine and uric acid in older Chinese patients with isolated systolic hypertension [PDF]

, 2001
UNLABELLED: We examined the relation of serum creatinine and uric acid to mortality and cardiovascular disease in older (aged >/=60 years) Chinese patients with isolated systolic hypertension (systolic/diastolic blood pressure >/=160/
Staessen, Jan A., for the Systolic Hypertension in China (Syst-China) Trial Collaborative Group, Wang, J.G., Fagard, Robert, Birkenhäger, W.H., Liu, L., Gong, L.   +6 more
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PECULIARITIES OF 24 HOUR AMBULATORY BLOOD PRESSURE MONITORING INDICES IN HYPERTENSIVE PATIENTS OF DIFFERENT AGE GROUPS

Медична наука України, 2022
Relevance. Until now, there is an ongoing debate about the value of different indicators of blood pressure (BP) − systolic blood pressure (SBP), diastolic blood pressure (DBP), pulse blood pressure (PBP) as predictors of essential hypertension (EH).
V.S. Pasko
doaj   +1 more source

Integrating Time‐Adjusted Imaging Instability Into Functional Outcome Prediction After Intracerebral Hemorrhage: Development and Validation of the HAGIV Score

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Early risk stratification may support clinical decision‐making in spontaneous intracerebral hemorrhage (ICH). We aimed to develop and internally validate HAGIV, a score integrating frequency of imaging markers (FIM), a time‐adjusted non‐contrast computed tomography (CT) metric of hematoma expansion, with established predictors for 90‐
Lei Song, Ren Ke, Anqi Chen, Yufei Fu, Hang Zhou, Rujia Wang, Liwei Zou, Yongqiang Yu, Ming Yuan, Xiaoming Qiu, Mengzhou Xue   +10 more
wiley   +1 more source

Improved ventricular function during inhalation of PGI(2) aerosol partly relies on enhanced myocardial contractility [PDF]

, 2005
Inhaled prostacyclin (PGI(2)) aerosol induces selective pulmonary vasodilation. Further, it improves right ventricular ( RV) function, which may largely rely on pulmonary vasodilation, but also on enhanced myocardial contractility.
Thein, E., Kisch-Wedel, H., Kemming, G., Bruhn, S., Meisner, F., Meisner, D., Kreyling, W., Zwissler, B., Flondor, M., Kreyling, W.G., Zwissler, Bernhard, Hofstetter, C., Kemming, Gregor   +12 more
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Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Concentric left ventricular remodeling and aortic stiffness: a comparison of obesity and hypertension. [PDF]

, 2013
BACKGROUND: Increased thoracic ascending aortic stiffness is thought to contribute to concentric left ventricular hypertrophy and increased mortality, a pattern seen in hypertension.
Francis, JM, Rider, OJ, Nethononda, R, Petersen, SE, Neubauer, Stefan, Francis, Jane M., Rider, Oliver J., Petersen, Steffen E., Neubauer, S, Nethononda, Richard, Clarke, Kieran, Byrne, James, Clarke, K, Byrne, JP, Leeson, P, Leeson, Paul   +15 more
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ВЗАИМОСВЯЗИ ДИАСТОЛИЧЕСКОЙ ФУНКЦИИ ЛЕВОГО ЖЕЛУДОЧКА С ЕГО МОРФОФУНКЦИОНАЛЬНЫМИ ОСОБЕННОСТЯМИ, ПОКАЗАТЕЛЯМИ ПЕРИФЕРИЧЕСКОЙ ГЕМОДИНАМИКИ И ДАННЫМИ СУТОЧНОГО МОНИТОРИРОВАНИЯ АРТЕРИАЛЬНОГО ДАВЛЕНИЯ У ПАЦИЕНТОВ С АРТЕРИАЛЬНОЙ ГИПЕРТЕНЗИЕЙ

Архивъ внутренней медицины, 2014
Various disorders of the diastolic function of left ventricle are formed due to concentric and eccentric types of hypertrophy. The processes of elevation of myocardial stiffness and reduction of lard-bore arterial vessel elastance develop parallel and at
С. В. Самоявчева, Е. В. Гурвич, В. В. Шкарин   +2 more
doaj   +1 more source

Discordance Between Patient and Physician Global Assessments in Early Systemic Sclerosis

Arthritis Care &Research, EarlyView.
Objective This study aims to identify factors associated with patient global assessment (PtGA) and physician global assessment (PhGA) and discordance between them in systemic sclerosis (SSc). Methods Data from adults with early SSc (<5 years) from the Collaborative National Quality and Efficacy Registry were included.
Ellen Romich, Alexis Ogdie, Alisa Stephens Shields, Peter A. Merkel, Shervin Assassi, Elana J. Bernstein, Andreea Bujor, Flavia V. Castelino, Lorinda Chung, Luke B. Evnin, Tracy M. Frech, Jessica K. Gordon, Melissa Griffith, Faye N. Hant, Monica L. Harding, Laura K. Hummers, Dinesh Khanna, Kimberly S. Lakin, Dorota J. Lebiedz‐Odrobina, Yiming Luo, Ashima Makol, Maureen D. Mayes, Zsuzsanna H. McMahan, Jerry Molitor, Duncan F. Moore, Julie Paik, Carrie Richardson, Brian Skaug, Ami A. Shah, Ankoor Shah, Virginia Steen, John M. VanBuren, Elizabeth R. Volkmann, Carleigh Zahn, Nora Sandorfi, for the CONQUER Investigators   +35 more
wiley   +1 more source

Isolated Biventricular Noncompaction in an adult with severe pulmonary hypertension : an association reviewed. [PDF]

, 2012
Biventricular noncompaction is a recently recognized rare form of cardiomyopathy. It is characterized by altered structure of myocardial wall as a result of intrauterine arrest of compaction of the myocardial fibers in absence of coexisting congenital
Awasthy, Neeraj, Tomar, Munesh, Radhakrishnan, Sitaraman   +2 more
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