Results 21 to 30 of about 1,769,882 (266)

Gut microbiota Turicibacter strains differentially modify bile acids and host lipids

open access: yesNature Communications, 2023
Bacteria from the Turicibacter genus are prominent members of the mammalian gut microbiota and correlate with alterations in dietary fat and body weight, but the specific connections between these symbionts and host physiology are poorly understood.
Jonathan B. Lynch   +9 more
doaj   +1 more source

Chemistry, Biological Activities and In Silico Bioprospection of Sterols and Triterpenes from Mexican Columnar Cactaceae

open access: yesMolecules, 2020
The Cactaceae family is an important source of triterpenes and sterols. The wide uses of those plants include food, gathering, medicinal, and live fences. Several studies have led to the isolation and characterization of many bioactive compounds.
Juan Rodrigo Salazar   +2 more
doaj   +1 more source

Not reimbursing islet transplantation creates discrimination against patients with type 1 diabetes [PDF]

open access: yesCellR4, 2019
In this commentary reviewing the activity of the University of Geneva islet transplantation program, the author argues that health care coverage of the procedure will stop discrimination against a subset of patients with type 1 diabetes in need of beta ...
T. Berney
doaj   +1 more source

Insulin-producing organoids engineered from islet and amniotic epithelial cells to treat diabetes

open access: yesNature Communications, 2019
Islet transplantation is a feasible approach to treat type I diabetes, however inflammation and poor vascularisation impair long-term engraftment. Here the authors show that incorporating human amniotic epithelial cells into islet organoids improves ...
Fanny Lebreton   +13 more
doaj   +1 more source

In Silico Study of Polyunsaturated Fatty Acids as Potential SARS-CoV-2 Spike Protein Closed Conformation Stabilizers: Epidemiological and Computational Approaches

open access: yesMolecules, 2021
SARS-CoV-2 infects host cells by interacting its spike protein with surface angiotensin-converting enzyme 2 (ACE2) receptors, expressed in lung and other cell types.
Alonso Vivar-Sierra   +7 more
doaj   +1 more source

In Combo Studies for the Optimization of 5-Aminoanthranilic Acid Derivatives as Potential Multitarget Drugs for the Management of Metabolic Syndrome

open access: yesPharmaceuticals, 2022
Metabolic syndrome is a set of risk factors that consist of abdominal obesity, arterial hypertension, alterations in the lipid profile, and hyperglycemia.
Edwin Chávez-Gutiérrez   +13 more
doaj   +1 more source

Impact of vaccination on COVID-19 severity during the second wave in Brunei Darussalam, 2021

open access: yesWestern Pacific Surveillance and Response
Objective: Coronavirus disease (COVID-19) vaccinations have been shown to prevent infection with efficacies ranging from 50% to 95%. This study assesses the impact of vaccination on the clinical severity of COVID-19 during the second wave in Brunei ...
Chee Fui Chong   +9 more
doaj   +1 more source

Disposal of High-Level Nuclear Waste in Deep Horizontal Drillholes

open access: yesEnergies, 2019
Spent nuclear fuel and high-level radioactive waste can be disposed in deep horizontal drillholes in sedimentary, metamorphic or igneous rocks. Horizontal drillhole disposal has safety, operational and economic benefits: the repository is deep in the ...
Richard A. Muller   +7 more
doaj   +1 more source

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