Results 151 to 160 of about 82,044 (253)

Physics‐Informed Machine Learning for Sustainable Alloy Design: Toward a Recyclable Unified Q&P Steel

open access: yesAdvanced Science, EarlyView.
A physics‐informed property‐bridging framework links high‐throughput hardness screening to tensile performance in quenching and partitioning steels. By transferring metallurgically guided representations across properties, a single alloy composition is designed to achieve multiple strength grades through heat‐treatment tuning alone, offering a ...
Xiaolu Wei   +7 more
wiley   +1 more source

mTORC2 Phosphorylation of GSDME‐N Drives Cullin4B‐Mediated Proteasomal Degradation to Suppress Pyroptosis and Confer Radioresistance in Small Cell Lung Cancer

open access: yesAdvanced Science, EarlyView.
Radioresistance severely limits the efficacy of therapies for small cell lung cancer (SCLC). This study reveals a novel mechanism of resistance driven by the active suppression of pyroptosis. Specifically, the mTORC2 complex directly phosphorylates GSDME‐N and promotes its CUL4B‐mediated ubiquitination and proteasomal degradation.
Qing‐qing Xu   +11 more
wiley   +1 more source

Extra Climate Benefits From Afforestation Due to Reduced Forest Fragmentation in China

open access: yesAdvanced Science, EarlyView.
Afforestation in China reduced forest fragmentation in 2015, transforming 51.8 M ha of edge forests into interior forests. This enhanced carbon sequestration (1.4±0.2 Pg CO2e, a cooling biogeochemical effect), while reduced albedo (−0.9 Pg CO2e, a warming biophysical effect) partially offset the gain, yielding a net extra climate benefit of ...
Nan Meng   +19 more
wiley   +1 more source

Resistant Peanut Genotype Reprograms Rhizosphere Metabolism to Enhance Bacterial Wilt Suppression

open access: yesAdvanced Science, EarlyView.
The resistant peanut genotype selectively recruits beneficial bacteria, which coincides with the activation of salicylic acid (SA)‐dependent systemic acquired resistance (SAR) against Ralstonia solanacearum. Keystone rhizosphere metabolites are positively correlated with both beneficial microbiome assembly and SAR gene expression.
Rui Ren   +20 more
wiley   +1 more source

Empirical Superior Vena Cava Isolation Added to Pulmonary Vein Isolation in Atrial Fibrillation: A Systematic Review and Meta-Analysis. [PDF]

open access: yesBMC Cardiovasc Disord
Muhammad Haris H   +14 more
europepmc   +1 more source

Multi‐Stimuli‐Responsive Hydrogen‐Bonded Organic Frameworks Nanocarriers Enable Targeted Fungicide Release and Plant Immune Regulation

open access: yesAdvanced Science, EarlyView.
A fluorinated hydrogen‐bonded organic framework nanocarrier (PFC‐1‐F) loaded with PYR and coated with HACC enables multi‐stimuli‐responsive (enzyme/ROS/pH) release at infection sites. Exhibiting targeted antifungal activity against Sclerotium rolfsii, modulating plant antioxidant defense, and demonstrating favorable biosafety across plant, soil, and ...
Guangming Ma   +6 more
wiley   +1 more source

Diversity and extracellular enzymatic activity of culturable yeasts isolated from soil in a Brazilian Amazonian rainforest biome. [PDF]

open access: yesBraz J Microbiol
Santos ARO   +7 more
europepmc   +1 more source

Federated Isolation Forest

open access: yesJournal of Korea Multimedia Society
Sung-Won Kang, Cheong-Hee Park
openaire   +1 more source

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian   +13 more
wiley   +1 more source

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