Results 121 to 130 of about 323,080 (268)

OGFRL1 Deficiency Causes Chronic Recurrent Multifocal Osteomyelitis Via Pathologic Osteoclastogenesis, With Therapeutic Response to Tumor Necrosis Factor Inhibitor

Arthritis &Rheumatology, EarlyView.
Objective To verify the pathogenesis of the opioid growth factor receptor like‐1 (OGFRL1) loss‐of‐function variant (c.30del, p. F10Ffs*110) identified in a patient with chronic recurrent multifocal osteomyelitis (CRMO) and to investigate the underlying mechanism.
Wen Xiong, Yusha Wang, Tingyan He, Jinjian Fu, Ying Luo, Jinbo Wang, Jun Wang, Xiaomin Yu, Qing Zhou, Jun Yang   +9 more
wiley   +1 more source

Bacterial Pigments as Potential Antitumor Agents Against Gastrointestinal Cancers: A Comprehensive Systematic Review

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Gastrointestinal cancers (GICs) constitute one of the leading causes of cancer‐related morbidity and mortality worldwide. Despite currently available therapeutic strategies, new approaches and procedures are needed for their prevention and treatment.
Raúl Vergara, Ricardo F. S. Pereira, Carla C. C. R. de Carvalho, Jose Prados, Consolación Melguizo, Raul Ortiz   +5 more
wiley   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

British Journal of Clinical Pharmacology, EarlyView.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga, Stefano Agliardi, Riccardo Giossi, Alice Schianchi, Alessandra Romandini, Thomas Virdis, Silvia Nerini Molteni, Maria Luisa De Angelis, Stefania Paccagnini, Cecilia Gechtman, Alice Proto, Marco Fossati, Silvia Oliveri, Giulia Angela Pattarino, Elena Altieri, Agnese Graziosi, Arianna Pani, Romano Danesi, Stefano Martinelli, Costantino De Giacomo, Francesco Scaglione   +20 more
wiley   +1 more source

Impact of a One‐Week Bioengineering Outreach Activity on the Academic Perceptions and Motivation of High School Students

Biochemistry and Molecular Biology Education, EarlyView.
ABSTRACT Many universities across Europe have developed outreach programs to bring high school students closer to science and help them make more informed decisions about their academic futures. At the University of Porto (Portugal), the Junior University is a summer school that offers research and development activities on specific topics, enabling ...
J. S. Sousa, B. M. P. Gonçalves, C. Ferreira, J. M. Rocha, S. Faia, L. C. Simões, M. Simões   +6 more
wiley   +1 more source

Advanced nanotherapeutics for combating ocular infections: Rational design, antimicrobial mechanisms, and therapeutic breakthroughs

BMEMat, EarlyView.
Nanomaterials revolutionize ocular infection treatment by enabling targeted drug delivery and enhanced antimicrobial efficacy against resistant pathogens. This review systematically explores their rational design, multimodal mechanisms, and translational potential for next‐generation anti‐infective therapies.
Yujia Liu, Xuetian Wen, Yue Tan, Rui Zeng, Yijuan Zhang, Tong Lin, Lan Gong, Zichao Luo   +7 more
wiley   +1 more source

Correction: NAxtra magnetic nanoparticles for low-cost, efficient isolation of mammalian DNA and RNA. [PDF]

Sci Rep
Starheim EJ, Ravlo E, Schjølberg JO, Solvang V, Wang W, Scrimgeour NR, Manaf A, Erlandsen SE, Aas PA, Hagen L, de Sousa MML, Bjørås M.   +11 more
europepmc   +1 more source

Injuries in deep time: interpreting competitive behaviours in extinct reptiles via palaeopathology

Biological Reviews, EarlyView.
ABSTRACT For over a century, palaeopathology has been used as a tool for understanding evolution, disease in past communities and populations, and to interpret behaviour of extinct taxa. Physical traumas in particular have frequently been the justification for interpretations about aggressive and even competitive behaviours in extinct taxa.
Maximilian Scott, Julia A. Gamble, Caleb Marshall Brown, Kirstin S. Brink   +3 more
wiley   +1 more source

A 5-year review of <i>Helicobacter pylori</i> isolated from gastric biopsies at the UK Health Security Agency Gastrointestinal Bacteria Reference Unit. [PDF]

J Med Microbiol
Swift C, Jenkins C, Chattaway MA, Wong V, Ready D, Godbole G.   +5 more
europepmc   +1 more source

A review of the historic and present ecological role of aquatic and shoreline wood, from forest to deep sea

Biological Reviews, EarlyView.
ABSTRACT The ecology of forests, their losses, and terrestrial wood decomposition dynamics have been intensively studied and reviewed. In the aquatic realm, reviews have concentrated on large wood (LW) in rivers and the transition from freshwater to marine environments in the Pacific Northwest of North America. However, a comprehensive global synthesis
Jon Dickson, Ellen Wohl, Laura L. Govers, Oscar Franken, Tjeerd J. Bouma, Han Olff, Britas Klemens Eriksson, Maryann S. Watson, Luísa M.S. Borges, Tjisse van der Heide   +9 more
wiley   +1 more source

Draft genome sequences of three <i>Streptomyces</i> sp. strains isolated from marine sponges in Kochi Prefecture, Japan. [PDF]

Microbiol Resour Announc
Hirano A, Matsubara Y, Okamura K, Sakurai T, Ulanova D.   +4 more
europepmc   +1 more source