Results 241 to 250 of about 333,047 (329)

Lienhwalides: Unique Tropolone–Maleidride Hybrids from Hypoxylon lienhwacheense

open access: yesChemBioChem, EarlyView.
Lienhwalides are novel tropolone–maleidride hybrid molecules unique in nature. Absolute configuration is solved by semisynthetic approaches and X‐ray analysis. Interplay between both lwt and lwm biosynthetic gene clusters is responsible for the production of lienhwalides.
Katharina Schmidt   +13 more
wiley   +1 more source

Pioneering Women Shaping the Field of Biocatalysis

open access: yesChemCatChem, EarlyView.
Groundbreaking works of women scientists in biocatalysis are highlighted in this article. Their innovative contributions are categorized in four interrelated research areas, collectively driving advancements in enzymatic biotransformations. Abstract In this perspective article, we celebrate the accomplishments of female‐led research groups in ...
Ana I. Benítez‐Mateos   +3 more
wiley   +1 more source

Citizen Science to Raise Antimicrobial Resistance Awareness in the Community: The MicroMundo Project in Spain and Portugal. [PDF]

open access: yesMicrob Biotechnol
Gil-Serna J   +41 more
europepmc   +1 more source

Tryptophan‐Selective Chemical Modification of Peptides by Thioether‐Mediated Sulfenylation

open access: yesChemistryEurope, EarlyView.
A thioether‐mediated sulfenylation method based on 4‐fluorophenyl 3‐nitro‐2‐pyridinesulfenate (Npys‐OPh(pF)) is developed for Trp‐selective chemical modification. This sulfenylation proceeds under mild, metal‐free, and weakly acidic conditions and is broadly applicable to the chemical modification of various Trp‐containing peptides as well as the late ...
Hayate Shida   +11 more
wiley   +1 more source

Persistence in time: the hunt for <i>Bacillus anthracis</i> at a historic tannery site in Austria reveals genetic diversity thought extinct. [PDF]

open access: yesAppl Environ Microbiol
Mayerhofer-Rochel MF   +8 more
europepmc   +1 more source

Total Synthesis of Kanamycins

open access: yesChemistry – A European Journal, Accepted Article.
Structurally‐modified aminoglycosides, such as kanamycin, have shown promise as antibiotics and premature termination codon read‐through drugs to fight against drug‐resistant bacteria and to treat genetic diseases, respectively. Therefore, research on developing and discovering aminoglycoside antibiotics has recently increased.
Kanae Hosomi   +7 more
wiley   +1 more source

In Vitro Psilocybin Synthesis by Co‐Immobilized Enzymes

open access: yesChemistry – A European Journal, EarlyView.
The drug candidate and psychedelic mushroom product psilocybin was produced by multienzyme‐charged beads in a biocatalytic cell‐free approach. Using immobilized fungal indolethylamine biosynthetic and additional bacterial enzymes, these beads turned over 4‐hydroxy‐l‐tryptophan to psilocybin.
Tim Schäfer   +7 more
wiley   +1 more source

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