Results 241 to 250 of about 31,445 (305)

Subglacial landscape formation and sediment discharge: relating basal conditions to bedform dimensions and properties at Rutford Ice Stream, West Antarctica

open access: yesBoreas, EarlyView.
Basal conditions that facilitate fast ice flow are still poorly understood and their parameterization in ice‐flow models results in high uncertainties in ice‐flow and consequent sea‐level rise projections. Direct observations of basal conditions beneath modern ice streams are limited due to the inaccessibility of the bed.
Rebecca Schlegel   +5 more
wiley   +1 more source

Living on the edge: Pleistocene ice‐free refugia and collared lemming (Dicrostonyx sp.) in the North American High Arctic

open access: yesBoreas, EarlyView.
Comparing the morphological variation of North American collared lemming with climatic and geographic features, as well as genetic insight and the ice sheet extend, indicate the strong geographic structure underlying the morphological diversity of the genus, that might be linked with a local Pleistocene survival in the High Arctic.
Louis Arbez   +4 more
wiley   +1 more source

Characterisation of the novel quinoline RCD405: Relaxant effects on cholinergic and histaminergic tone in human bronchi and small airways

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Increased contractility of human airway smooth muscle (hASM) is a hallmark of asthma and chronic obstructive pulmonary disease (COPD). Developing new classes of bronchodilators has proved to be challenging because of efficacy and safety concerns.
Paola Rogliani   +4 more
wiley   +1 more source

Clinically relevant niclosamide concentrations modulate TMEM16A and CaV1.2 channels to control artery tone and capillary diameter

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose TMEM16A Ca2+‐gated Cl− channels mediate depolarisation of contractile vascular cells. The anthelmintic niclosamide was reported to modulate the TMEM16A channel, suggesting possible repurposing for vascular pharmacology. Here, we investigate the mechanism of TMEM16A modulation by niclosamide and explore its effect on the ...
Rachel Kaye   +5 more
wiley   +1 more source

The thoracic perivascular adipose tissue spontaneously induces vasoconstriction through activation of α1‐adrenoceptors

open access: yesBritish Journal of Pharmacology, EarlyView.
Background and Purpose Although perivascular adipose tissue (PVAT) contains substances with contractile properties, its actions on the vascular tone are associated with the release of anticontractile substances. We hypothesize that procontractile PVAT products also exert direct effects on vascular tone. Experimental Approach Thoracic aortas from Wistar
Leonardo Gomes‐Pereira   +1 more
wiley   +1 more source

New perspectives on body size and shape evolution in dinosaurs

open access: yesBiological Reviews, EarlyView.
ABSTRACT Diversity in the body shapes and sizes of dinosaurs was foundational to their widespread success during the Mesozoic era. The ability to quantify body size and form reliably is therefore critical to the study of dinosaur biology and evolution.
Matthew Dempsey   +4 more
wiley   +1 more source

Neural Geometry Processing via Spherical Neural Surfaces

open access: yesComputer Graphics Forum, EarlyView.
Abstract Neural surfaces (e.g., neural map encoding, deep implicit, and neural radiance fields) have recently gained popularity because of their generic structure (e.g., multi‐layer perceptron) and easy integration with modern learning‐based setups. Traditionally, we have a rich toolbox of geometry processing algorithms designed for polygonal meshes to
Romy Williamson, Niloy J. Mitra
wiley   +1 more source

Isometric exercise, isometric strength and anthropometric measurements

Internationale Zeitschrift f�r Angewandte Physiologie Einschliesslich Arbeitsphysiologie, 1963
1. 29 young adult male subjects practiced 15 sec. of maximal isometric contractions of the elbow flexors three times a day, 5 days a week, for 5 weeks. They achieved greater increases in strength than have been claimed for a single two-thirds maximal contraction once a day, although the latter has been said to provide the maximal stimulus for the ...
Philip J. Rasch, William R. Pierson
openaire   +3 more sources

Energetics of isometric exercise in man

Journal of Applied Physiology, 1976
In isometric contractions of the plantar flexors (5–40% of maximal tension, Tmax), VO2 is linearly related to the force exerted, averaging 2 ml/min-kg of tension. At tension levels above 5% Tmax the lactic acid contribution to the overall energy demand is constant at about 20%.
P. Cerretelli   +3 more
openaire   +4 more sources

Home - About - Disclaimer - Privacy