Results 111 to 120 of about 89,475 (303)

The possibility of using echocardiography in small laboratory animals for acute pharmacological tests

open access: yesФармакокинетика и Фармакодинамика, 2018
Resume. The purpose of this investigation is to study the adequacy of the echocardiography method in small laboratory animals for performing acute pharmacological tests.
E. O. Ionova   +4 more
doaj   +1 more source

Electrophysiological and arrhythmogenic effects of 5-hydroxytryptamine on human atrial cells are reduced in atrial fibrillation [PDF]

open access: yes, 2007
5-Hydroxytryptamine (5-HT) is proarrhythmic in atrial cells from patients in sinus rhythm (SR) via activation of 5-HT<sub>4</sub> receptors, but its effects in atrial cells from patients with atrial fibrillation (AF) are unknown.
Andrew C. Rankin   +44 more
core   +2 more sources

Heat Stress‐Mediated Multi‐Organ Injury: Pathophysiology and Treatment Strategies

open access: yesComprehensive Physiology, Volume 15, Issue 3, June 2025.
Thermal environment‐mediated pathophysiologic processes in the body and their coping strategies. ABSTRACT With global warming in recent years, humans have been subjected to the impact of thermal environments on both work and life. Improving the body's ability to withstand heat is an urgent task.
Xiaoqing Ding, Binghong Gao
wiley   +1 more source

Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes[S]

open access: yesJournal of Lipid Research, 2011
The lipid droplet-associated fat specific protein 27 (FSP27) suppresses lipolysis and thereby enhances triglyceride accumulation in adipocytes. We and others have recently found FSP27 to be a remarkably short-lived protein (half-life, 15 min) due to its ...
S. Ranjit   +8 more
semanticscholar   +1 more source

ADENYLYL CYCLASE TYPE 9: REGULATION AND CARDIAC FUNCTION [PDF]

open access: yes, 2018
Abnormalities in cardiac stress signaling underlie a number of cardiovascular diseases (e.g. arrhythmias and heart failure). Cardiac stress signaling pathways normally integrate signals from the sympathetic nervous system to promote efficient contraction
Baldwin, Tanya A., Baldwin, Tanya A.
core   +1 more source

Phosphorylation of protein kinase A (PKA) regulatory subunit RIα by protein kinase G (PKG) primes PKA for catalytic activity in cells. [PDF]

open access: yes, 2018
cAMP-dependent protein kinase (PKAc) is a pivotal signaling protein in eukaryotic cells. PKAc has two well-characterized regulatory subunit proteins, RI and RII (each having α and β isoforms), which keep the PKAc catalytic subunit in a catalytically ...
Casteel, Darren E   +5 more
core   +1 more source

Immune cell dynamics in heart failure: implicated mechanisms and therapeutic targets

open access: yesESC Heart Failure, Volume 12, Issue 3, Page 1739-1758, June 2025.
Abstract The relationship between heart failure (HF) and immune activation has garnered significant interest. Studies highlight the critical role of inflammation in HF, affecting cardiac structure and function. Despite promising anti‐inflammatory therapies, clinical trials have faced challenges, indicating an incomplete understanding of immune ...
Gen Li, Wu He, Dao Wen Wang
wiley   +1 more source

Characteristics of atrioventricular block during slow pathway ablation for atrioventricular nodal re‐entrant tachycardia: A comparative study of cryoablation and radiofrequency ablation

open access: yesJournal of Arrhythmia, Volume 41, Issue 3, June 2025.
This study aimed to investigate the differences in the appearance of atrioventricular block (AVB) between cryoablation and radiofrequency (RF) ablation for atrioventricular nodal re‐entrant tachycardia (AVNRT). Our findings revealed that cryoablation for AVNRT has a higher incidence of transient AVB than RF ablation.
Shinichi Tachibana   +8 more
wiley   +1 more source

Sulfated polysaccharides of Turbinaria conoides dose-dependently mitigate oxidative stress by ameliorating antioxidants in isoproterenol induced myocardial injured rats: Evidence from histopathological study

open access: yesThe Egyptian Heart Journal, 2012
Objectives: In recent years, fucoidan is being marketed as a nutraceutical and food supplement because of its various pharmacological activity.
Krishnamoorthy Mohankumar   +3 more
doaj   +1 more source

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