Results 111 to 120 of about 93,473 (332)

Contribution of Sympathetic Sensory Coupling to Craniofacial Nociception

open access: yesOrthodontics &Craniofacial Research, EarlyView.
ABSTRACT Stress and anxiety are associated with increased pain intensity in temporomandibular disorders (TMDs) patients. It is possible that this association is due to a direct interaction between the sympathetic and sensory nervous systems. This narrative review examines evidence for a potential sympathetic sensory interaction in deep craniofacial ...
Brian Edwin Cairns
wiley   +1 more source

ER/K linked GPCR-G protein fusions systematically modulate second messenger response in cells. [PDF]

open access: yes, 2017
FRET and BRET approaches are well established for detecting ligand induced GPCR-G protein interactions in cells. Currently, FRET/BRET assays rely on co-expression of GPCR and G protein, and hence depend on the stoichiometry and expression levels of the ...
Dysthe, Matthew   +4 more
core   +1 more source

Cardiomyocyte ryanodine receptor clusters expand and coalesce after application of isoproterenol [PDF]

open access: hybrid, 2023
David R.L. Scriven   +4 more
openalex   +1 more source

The skeletal muscle–adipose creatine metabolic axis: A novel paradigm for lipid metabolism reprogramming and obesity management

open access: yesExperimental Physiology, EarlyView.
Abstract The global prevalence of obesity and related metabolic disorders has spurred interdisciplinary research to develop new intervention strategies. Current research is increasingly focusing on the exercise‐induced browning of white adipose tissue and the mechanisms by which it improves energy metabolism.
Yuhui Su   +4 more
wiley   +1 more source

Na+,-K+-ATPase Deficiency Exacerbates Cardiac Fibrosis via Promoting ERRα-Mediated Myocardial Cell Injury and Macrophage Activation Under Isoproterenol-Challenged Conditions

open access: yesFrontiers in Bioscience-Landmark
Background: Inflammation plays a pivotal role in the progression of tissue fibrosis. Our previous research demonstrated that Na+, K+-ATPase (NKA) α1 deficiency impairs mitochondrial function and accelerates isoproterenol (ISO)-induced ...
Ting Lei   +7 more
doaj   +1 more source

Regulation of fat specific protein 27 by isoproterenol and TNF-α to control lipolysis in murine adipocytes[S]

open access: yesJournal of Lipid Research, 2011
The lipid droplet-associated fat specific protein 27 (FSP27) suppresses lipolysis and thereby enhances triglyceride accumulation in adipocytes. We and others have recently found FSP27 to be a remarkably short-lived protein (half-life, 15 min) due to its ...
S. Ranjit   +8 more
semanticscholar   +1 more source

Cardiac‐specific Kv1.1 deficiency alters cardiomyocyte electrophysiology without modifying overall cardiac function or arrhythmia susceptibility

open access: yesExperimental Physiology, EarlyView.
Abstract The leading cause of epilepsy‐related mortality is sudden unexpected death in epilepsy (SUDEP), resulting from seizure‐induced cardiorespiratory arrest by mechanisms that remain unresolved. Mutations in ion channel genes expressed in both brain and heart represent SUDEP risk factors because they can disrupt neural and cardiac rhythms ...
Kelsey Halvorson   +11 more
wiley   +1 more source

Glial cells in the heart: Implications for their roles in health and disease

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya   +2 more
wiley   +1 more source

β-Caryophyllene as a Potential Protective Agent Against Myocardial Injury: The Role of Toll-Like Receptors

open access: yesMolecules, 2019
Myocardial infarction (MI) remains one of the major causes of mortality around the world. A possible mechanism involved in myocardial infarction is the engagement of Toll-like receptors (TLRs).
Nancy S. Younis, Maged E. Mohamed
doaj   +1 more source

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