Results 151 to 160 of about 80,153 (209)

The isoquinoline alkaloids

1971
1. ISOQUINOLINE ALKALOIDS - ORIGINS AND DEGREDATION 2. ss-PHENYLETHYLAMINES AND SIMPLE ISOQUINOLINES 2.1 Structures 2.2 Syntheses 2.3 Chemical Properties 2.4 Polymeric Isoquinolines 2.5 N-Benzylisoquinolines 2.6 1-Phenylisoquinolines 2.7 4-Phenylisoquinolines 2.8 Biogenesis 2.9 Pharmacology References 3.
J. E. Saxton, K. W. Bentley
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The Pyrrolo[2,1-a]isoquinoline Alkaloids

2011
The present chapter describes isolation, biogenetic proposals, and syntheses of the natural products 1-4 and 10-11 with a pyrrolo[2,1-a]-isoquinoline framework. Moreover, the syntheses of some structural analogs are discussed. The pyrrolo[2,1-a]isoquinolines are of interest due to their promising biological activities.
Ulrike, Pässler, Hans-Joachim, Knölker
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Isoquinoline Alkaloids and Chemotaxonomy

2019
The isoquinoline alkaloids are a class of secondary metabolites classified into different groups, being the aporphinoids the most representative class. They are considered the second-largest class of alkaloids in terms of structural diversity staying behind only of indole alkaloids.
Anderson R. dos Santos, Nelissa P. Vaz
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Isoquinoline alkaloids as prolyl oligopeptidase inhibitors

Fitoterapia, 2015
Prolyl oligopeptidase is a cytosolic serine peptidase that hydrolyses proline-containing peptides at the carboxy terminus of proline residues. It has been associated with schizophrenia, bipolar affective disorder, and related neuropsychiatric disorders and therefore may have important clinical implications.
Lucie, Cahlíková, Lucie, Hulová, Martina, Hrabinová, Jakub, Chlebek, Anna, Hošťálková, Markéta, Adamcová, Marcela, Šafratová, Daniel, Jun, Lubomír, Opletal, Miroslav, Ločárek, Kateřina, Macáková   +10 more
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Antimicrobial Activity of Some Isoquinoline Alkaloids

Archiv der Pharmazie, 1991
AbstractThe isoquinoline alkaloids are of great importance to humanity because of their medicinal value and different structure. During the last ten years, many isoquinoline alkaloids were isolated from Fumaria and Corydalis species growing in Turkey1—6).There have been many researches on the antimicrobial activity of extracts of higher plants, but ...
U, Abbasoglu, B, Sener, Y, Günay, H, Temizer   +3 more
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Metabolic Engineering in Isoquinoline Alkaloid Biosynthesis

Current Pharmaceutical Biotechnology, 2007
Higher plants produce diverse classes of metabolites. Metabolic engineering offers tremendous potential to improve the production and quality of these chemicals. This report summarizes the possibility of using metabolic engineering in benzylisoquinoline alkaloid biosynthesis.
Fumihiko, Sato, Takayuki, Inui, Tomoya, Takemura   +2 more
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Extractions of isoquinoline alkaloids with butanol and octanol

Fitoterapia, 2010
Six different isoquinoline alkaloids (sanguinarine, chelerythrine, berberine, coptisine, allocryptopine, and protopine) were extracted by butanol and octanol from aqueous solution, pH 4.5. The samples were analyzed by HPLC. Butanol extraction was non-selective, alkaloids passed into organic phase in 83-98%.
Jana, Gregorová, Jan, Babica, Radek, Marek, Hana, Paulová, Eva, Táborská, Jirí, Dostál   +5 more
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Isoquinoline alkaloids

Neurochemical Research, 1978
Representatives of eleven different classes of isoquinoline alkaloids inhibit Na+, K+-ATPase and Mg2+-ATPase in rat brain microsomal preparations. In most cases the Na+, K+-ATPase is more sensitive than Mg2+-ATPase to inhibition by the alkaloids.
L R, Meyerson, K D, McMurtrey, V E, Davis   +2 more
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The Biosynthesis of Isoquinoline Alkaloids

1985
The tetrahydroisoquinoline skeleton occurs in numerous plant alkaloids. The simplest bearers of this structural unit are exemplified by anhalonidine (12) (Sect. 2). Slightly more elaborate are the benzylisoquinoline alkaloids exemplified at their simplest by reticuline (25) and papaverine (27) (Sect. 3).
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Isoquinoline and Benzylisoquinoline Alkaloids

1998
Alkaloids that possess an isoquinoline moiety in their structure are among the most common of all alkaloids. More than 4000 compounds of many structural types but with this structural feature are known (Verpoorte et al., 1991). Those treated in this chapter are all derived from a 3,4-dihydroxytyramine (dopamine) precursor that is linked to an aldehyde ...
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