Clinical and Translational Science, 2022 Vericiguat was developed for the treatment of symptomatic chronic heart failure (HF) in adult patients with reduced ejection fraction who are stabilized after a recent decompensation event.
Michael Boettcher +11 more
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The future of isosorbide as a fundamental constituent for polycarbonates and polyurethanes
Green Chemistry Letters and Reviews, 2021 Isosorbide is a biobased compound which could become in the near future an advantageous competitor of petroleum-derived components in the synthesis of polymers of different nature.
Olga Gómez-de-Miranda-Jiménez-de-Aberasturi +11 more
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Ultra‐Tough Elastomers from Stereochemistry‐Directed Hydrogen Bonding in Isosorbide‐Based Polymers
Angewandte Chemie - International Edition, 2022 The remarkable elasticity and tensile strength found in natural elastomers are challenging to mimic. Synthetic elastomers typically feature covalently cross‐linked networks (rubbers), but this hinders their reprocessability.
Hannah Prydderch +2 more
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Catalytic Properties of Microporous Zeolite Catalysts in Synthesis of Isosorbide from Sorbitol by Dehydration [PDF]
Catalysts, 2020 As bisphenol A has been found to cause hormonal disturbances, the natural biomaterial isosorbide is emerging as a substitute. In this study, a method for isosorbide synthesis from sorbitol was proposed by dehydration under high temperature and high ...
Sangmin Jeong +5 more
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Novel role of isosorbide as a biostimulant in enhancing plant growth and development in Arabidopsis thaliana [PDF]
BMC Plant BiologySustainable agriculture faces growing challenges in boosting food production while minimizing environmental impact, highlighting the need for innovative solutions.
Raj Kishan Agrahari +3 more
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Reductive Hydroformylation of Isosorbide Diallyl Ether
Molecules, 2021 Isosorbide and its functionalized derivatives have numerous applications as bio-sourced building blocks. In this context, the synthesis of diols from isosorbide diallyl ether by hydrohydroxymethylation reaction is of extreme interest.
Jérémy Ternel +7 more
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Architectural Control of Isosorbide-Based Polyethers via Ring-Opening Polymerization
Journal of the American Chemical Society, 2019 Isosorbide is a rigid, sugar-derived building block that has shown promise in high-performance materials, albeit with a lack of available controlled polymerization methods.
Derek J Saxon +2 more
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One-pot synthesis of isosorbide from cellulose or lignocellulosic biomass: a challenge?
Beilstein Journal of Organic Chemistry, 2020 The catalytic conversion of (ligno)cellulose is currently subject of intense research. Isosorbide is one of the interesting products that can be produced from (ligno)cellulose as it can be used for the synthesis of a wide range of pharmaceuticals ...
Isaline Bonnin +3 more
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Eco-Friendly Adhesion of Isosorbide-Based Polycarbonate [PDF]
MoleculesWe investigated the practical adhesion of a conventional poly(vinyl alcohol) glue with a glassy isosorbide-based polycarbonate (ISB-PC) comprising isosorbide and 1,4-cyclohexanedimethanol.
Ruiqi Han +2 more
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Isosorbide Concentration in Perilymph of the Guinea Pig After Oral Administration Versus That After Round Window Perfusion [PDF]
Clinical and Experimental Otorhinolaryngology, 2014 ObjectivesThe aims of this study were to investigate the feasibility of isosorbide delivery into perilymph through the round window membrane (RWM), and to compare the intracochlear isosorbide concentration in perilymph after oral administration (PO ...
Minbum Kim, Kyung Hee Do, Kyu-Sung Kim
doaj +3 more sources