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Archives of Ophthalmology, 1967
Isosorbide is an effective hyperosmotic agent which can be administered orally without gastrointestinal irritation. It is absorbed quantitatively and more than 95% of the administered dose is excreted unchanged in the urine. Oral administration of a 50% solution to rabbits or man results in prompt increases in osmolarity of the serum and profound ...
B, Becker, A E, Kolker, T, Krupin
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Isosorbide is an effective hyperosmotic agent which can be administered orally without gastrointestinal irritation. It is absorbed quantitatively and more than 95% of the administered dose is excreted unchanged in the urine. Oral administration of a 50% solution to rabbits or man results in prompt increases in osmolarity of the serum and profound ...
B, Becker, A E, Kolker, T, Krupin
openaire +2 more sources
Isosorbide 5-Mononitrate Pharmacokinetics
Cardiology, 1987Isosorbide 5-mononitrate differs from other clinically used organic nitrate vasodilators because of its almost complete oral absorption, the low intersubject variability in its plasma concentrations and pharmacokinetic parameters, its relatively long half-life and its lack of active metabolites.
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Isosorbide dinitrate/isosorbide mononitrate/nitroglycerin
Reactions Weekly, 2004openaire +1 more source