Results 111 to 120 of about 5,973,776 (275)

Probing the Composition, Assembly and Activity of Protein Molecular Machines using Native Mass Spectrometry [PDF]

open access: yes, 2017
Native mass spectrometry and mass spectrometry in general, are powerful analytical tools for studying proteins and protein complexes. Native mass spectrometry may provide accurate mass measurements of large macromolecular assemblies enabling the ...
van de Waterbeemd, M.J.   +2 more
core  

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

open access: yesAdvanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer   +9 more
wiley   +1 more source

Isotope Mass Spectrometry in Meat Identification

open access: yesТехника и технология пищевых производств
Meat and meat products are consumed by a large proportion of the population. As a result, food scientists keep inventing new methods for meat identification, e.g., isotope mass spectrometry.
Lisitsyn Andrey   +5 more
doaj   +1 more source

isotope ratio mass spectrometry

open access: yes
Citation: 'isotope ratio mass spectrometry' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.12453 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

open access: yesAdvanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang   +22 more
wiley   +1 more source

Atomically Correlated Phosphorus–Sulfur Sites in Carbon Nitride for Efficient Hydrogen Peroxide Production

open access: yesAdvanced Science, EarlyView.
Atomically correlated phosphorus–sulphur sites are introduced into graphitic carbon nitride to regulate charge distribution, suppress localized trapping, and enhance oxygen activation. The resulting metal‐free photocatalyst selectively promotes the two‐electron oxygen reduction pathway, enabling efficient hydrogen peroxide production in pure water ...
Adnan Ahmad   +12 more
wiley   +1 more source

Locally Grown, Natural Ingredients? The Isotope Ratio Can Reveal a Lot!

open access: yesCHIMIA, 2016
This communication gives an overview of selected isotope analyses applied to food authenticity assessment. Different isotope ratio detection technologies such as isotope ratio mass spectrometry (IRMS) and cavity ring down spectroscopy (CRDS) are
Joël S. Rossier   +2 more
doaj   +1 more source

Quantification of methane oxidation in the rice rhizosphere using 13C-labelled methane [PDF]

open access: yes, 1994
In this paper isotope ratio mass spectrometry is used to determine the methane (CH4) oxidation fraction in the rhizosphere of intact rice plant-soil systems.
Harren, F.J.M.   +11 more
core   +3 more sources

Metal Active‐Site Exposure via Ligand Engineering Boosts CO2‐to‐Ethylene Conversion on Cu18 Nanoclusters

open access: yesAdvanced Science, EarlyView.
Through quantitative ligand stripping of [Cu18H17(PR3)10]+ nanoclusters via intramolecular interaction modulation, selectivity for CO2 electroreduction to C2H4 is significantly enhanced. The weakly coordinating ligand triggers dual‐ligand stripping (FEC2H4 = 70.59%), whereas the strongly coordinating ligand results in single‐ligand retention (FEC2H4 ...
Ziqi Chen   +8 more
wiley   +1 more source

Bond‐Competition‐Driven Enhancement of Surface Basicity and Interfacial Interaction to Boost Photocatalytic Syngas Production

open access: yesAdvanced Science, EarlyView.
A synergetic surface bond competition−hybridization approach was developed to synthesize high‐performance CO2 adsorbents and syngas production photocatalysts via the sulfurization‐driven control of surface basicity and interfacial coupling. The ZnIn2S4−sulfur‐doped MgO/MgAl2O4 nanocomposites showed outstanding photocatalytic efficiency for production ...
Dong Wook Lee   +9 more
wiley   +1 more source

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