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Profiling of urinary formestane and confirmation by isotope ratio mass spectrometry
Steroids, 2013Formestane (F, androst-4-en-4-ol-3,17-dione) is an irreversible aromatase inhibitor with the ability to suppress the estrogen production from anabolic steroids. Consequently, F is mentioned on the World Anti-Doping Agency (WADA) prohibited list and because studies have shown that F is produced endogenously in small amounts, a threshold for urinary ...
Michael, Polet +3 more
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Fast Gas Chromatography Combustion Isotope Ratio Mass Spectrometry
Analytical Chemistry, 2007We report here the first coupling of fast GC to IRMS, in a system capable of 250 ms peak widths (fwhm) at 1 mL/min flow rates, one-fifth as narrow as any previously reported GCC-IRMS system. We developed an optimized postcolumn interface that results in minimal peak broadening, using a programmable temperature vaporization injector in place of a rotary
Gavin L, Sacks +2 more
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Isotope Ratio Measurements with Elemental-Mode Electrospray Mass Spectrometry
Analytical Chemistry, 1996The isotope ratio capabilities of an electrospray ionization source interfaced to a quadrupole mass spectrometer are described. With the instrument operated in the metal ion mode, isotope measurements of Ag, Tl, and Pb are conducted using elemental ions produced from 1 × 10(-)(4) M solutions of metal nitrates or acetates in methanol.
M E, Ketterer, J P, Guzowski
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Acquisition and processing of data for isotope-ratio-monitoring mass spectrometry
Organic Geochemistry, 1994Methods are described for continuous monitoring of signals required for precise analyses of 13C, 18O, and 15N in gas streams containing varying quantities of CO2 and N2. The quantitative resolution (i.e. maximum performance in the absence of random errors) of these methods is adequate for determination of isotope ratios with an uncertainty of one part
M P, Ricci +3 more
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Analytical Chemistry, 2014
Generally, compound-specific isotope analysis of steroids is carried out by gas chromatography combined with isotope ratio mass spectrometry. Thus, a derivatization of the steroids prior to the measurement is compulsory, and a correction of the isotopic data is often necessary.
Zhang, Lijun +8 more
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Generally, compound-specific isotope analysis of steroids is carried out by gas chromatography combined with isotope ratio mass spectrometry. Thus, a derivatization of the steroids prior to the measurement is compulsory, and a correction of the isotopic data is often necessary.
Zhang, Lijun +8 more
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ForensicApplications of Isotope Ratio Mass Spectrometry
2003Meier-Augenstein, Wolfram, Liu, R.H.
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Mass spectrometry and natural variations of iron isotopes
Mass Spectrometry Reviews, 2006Nicolas Dauphas, Olivier Rouxel
exaly
Multi-isotope imaging mass spectrometry quantifies stem cell division and metabolism
Nature, 2012Matthew L Steinhauser +1 more
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