Lactate Signal: Modulator of Cellular Energy Production and Anabolism
Compartmentalized lactate signaling provides a spatial framework for understanding how lactate‐rich states are generated, transported, sensed, and translated into biological outputs. This Review integrates extracellular, cytosolic, mitochondrial‐associated, and nuclear lactate mechanisms to explain how lactate shapes metabolic adaptation, immune ...
Han Wang, Si‐Yuan Yang, Wei Xu
wiley +1 more source
Stable Isotope Labeling to Track De Novo Fatty Acid Synthesis in Mouse Cartilage-Enriched Joint Tissue In Vivo: A Practical Workflow. [PDF]
Moradi S, Binoy A, Zhu S.
europepmc +1 more source
A palladium membrane reactor delivers active hydrogen to homogeneous nickel terpyridine catalysts, which then selectively hydrogenate dinitrogen to ammonia. ABSTRACT Ammonia production is a cornerstone of modern industry and society, yet the conventional Haber–Bosch process accounts for nearly 2% of the global CO2 emissions. A promising and potentially
Morgan McKee +11 more
wiley +1 more source
Rapid consumption of H<sub>2</sub> in the deep subsurface. [PDF]
Xie H +9 more
europepmc +1 more source
By integrating knowledge‐augmented artificial intelligence with an oxygen‐supplemented 3D screening platform, a synergistic interaction between berberine and enzalutamide is identified. The framework integrates compound mechanisms of action with disease‐relevant signaling context to prioritize candidate combinations and generate testable pathway‐based ...
Chih‐Hui Lo +15 more
wiley +1 more source
Stable Isotope Composition of Skin Layers Confirms Trophic Differentiation of Baird's and Sato's Beaked Whales (Berardius spp.) in the Western North Pacific. [PDF]
Filatova OA +7 more
europepmc +1 more source
Robust NbN‐on‐Si/SiGe Hybrid Microwave Quantum Circuits With Long‐Term Stability
Superconducting NbN resonators integrated with Si/SiGe quantum wells based semiconducting chip are investigated as a CMOS–compatible platform for scalable quantum hardware. Temperature–dependent microwave spectroscopy reveals loss mechanisms from TLS, quasiparticles, and scattering.
Paniz Foshat +5 more
wiley +1 more source
Deer Antler δ<sup>18</sup>O Records Desalination in Israel's Water Supply. [PDF]
Laposki C, Darcy A, Werner N, Hartman G.
europepmc +1 more source
Stretchable Energy Storage with Eutectic Gallium Indium Alloy
A highly stretchable liquid metal‐based electrode is developed via a one‐step process, retaining conductivity and capacitance after mechanical deformation up to 900% strain. The stretchable all‐solid‐state device provides a areal energy density of 43 µWh cm⁻2 after 150% strain.
Adit Gupta +6 more
wiley +1 more source
Probing the Human 4-Oxo-l-proline Reductase-Catalyzed Reaction by Deuterium Kinetic and Equilibrium Isotope Effects. [PDF]
Pečaver E +4 more
europepmc +1 more source

