Results 221 to 230 of about 486,624 (356)

A Synergistic Complexation‐Encapsulation Paradigm Enables Unprecedented Radioactive Remediation

open access: yesAdvanced Science, EarlyView.
A novel HDEHP‐APG eutectic mixture‐based detergent is developed that achieves highly efficient decontamination of Am through a synergistic complexation‐encapsulation mechanism. Remarkably, such a detergent effectively removes radionuclides across a wide range of oxidation states (+I to +VII), demonstrating exceptional versatility.
Qilong Tang   +4 more
wiley   +1 more source

SIRT6 Lysine‐Demyristoylates ATF2 to Ameliorate Vascular Injury via PRKCD/VE‐Cadherin Pathway Regulating Vascular Endothelial Barrier

open access: yesAdvanced Science, EarlyView.
A novel modified SIRT6 variant (dSIRT6) H133Y‐mediated enrichment technique unmasks 15 new human lysine‐myristoylated proteins. Notably, Sirtuin 6 (SIRT6) demyristoylation of activating transcription factor 2 (ATF2) at K296 orchestrates its nucleoplasmic translocation.
Runyang Feng   +40 more
wiley   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

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