Results 241 to 250 of about 486,624 (356)

eIF4E Enriched Extracellular Vesicles Induce Immunosuppressive Macrophages through HMGCR‐Mediated Metabolic Rewiring

Advanced Science, EarlyView.
Here, it is revealed that ovarian cancer cells release extracellular vesicles enriched with eIF4E, which alters protein production in macrophages. This leads to increased expression of 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A reductase (HMGCR), boosting cholesterol synthesis and activating an immunosuppressive pathway through X‐box binding protein 1 and ...
Sonam Mittal, Minal Nenwani, Ishaque Pulikkal Kadamberi, Sudhir Kumar, Olamide Animasahun, Jasmine George, Shirng‐Wern Tsaih, Prachi Gupta, Mona Singh, Anjali Geethadevi, Chandrima Dey, Noah Meurs, Ajay Shankaran, Pradeep Chaluvally Raghavan, Deepak Nagrath, Sunila Pradeep   +15 more
wiley   +1 more source

Investigating long-term trophic stability in North Atlantic cod (<i>Gadus morhua</i>) through nitrogen stable isotope analysis of amino acids. [PDF]

Philos Trans R Soc Lond B Biol Sci
Yamoah AKK, Harland J, McLaughlin R, Talbot HM, Fontanals-Coll M, Craig OE, Orton D.   +6 more
europepmc   +1 more source

Mitochondrial Transplantation Augments the Reparative Capacity of Macrophages Following Myocardial Injury

Advanced Science, EarlyView.
Mitochondrial transplantation induces macrophage polarization toward an anti‐inflammatory M2 phenotype, enhances their reparative capacities, and facilitates mitochondrial transfer to cardiomyocytes, collectively promoting tissue repair and functional recovery post‐myocardial infarction.
Yuning Zhang, Xiaolei Sun, Yawei Jin, Kanghui Chen, Lu Zhang, Xiong Gao, Mohan Li, Ze Yuan, Jianguo Jia, Aijun Sun, Junbo Ge   +10 more
wiley   +1 more source

Chemometric Discrimination of the Geographical Origin of Rheum tanguticum by Stable Isotope Analysis. [PDF]

Foods
Nuralykyzy B, Nie J, Zhou G, Mei H, Zhao S, Li C, M Rogers K, Zhang Y, Yuan Y.   +8 more
europepmc   +1 more source

Inorganic trace analysis by isotope-dilution mass-spectrometry - New frontiers

, 1988
J. D. Fassett
openalex   +1 more source

FMO2 Promotes Angiogenesis via Regulation of N‐Acetylornithine

Advanced Science, EarlyView.
This study identifies flavin‐containing monooxygenase 2 (FMO2) as a novel proangiogenic regulator in endothelial cells. Targeted FMO2 ablation impairs vessel sprouting, whereas its compensation potently enhances angiogenesis. Metabolomics and single‐cell sequencing reveal that FMO2 drives vascular growth via the N‐acetylornithine/ATF3/NOTCH1 axis ...
Jingyi Wang, Yinghui Xu, Xianpeng Wu, Mo Li, Changchen Xiao, Zaiyang Fu, Yongjian Chen, Qingju Li, Yating Ruan, Jing Zhao, Zhiwei Zhong, Jinghai Chen, Wei Zhu, Jinliang Nan, Cheng Ni, Xinyang Hu   +15 more
wiley   +1 more source

Comparison Study on the Trophic Niche of Red Pandas Using Stable Isotope Analysis. [PDF]

Animals (Basel)
Zhang Y, Lei W, Luo W, Dai Q, Han H, Nie Y.   +5 more
europepmc   +1 more source

Determination of DNA by sub- and super-equivalence method of isotope dilution analysis using enzyme reaction.

, 1987
Hiroe Yoshioka, Tatsuya HISADA, Koichi Yoshinaga, K. Hasegawa, Nagao IKEDA   +4 more
openalex   +2 more sources

Comprehensive Genetic Map of Muscle Lipidome Reveals Novel Insights Into Flavor Variation in Ruminant Meat

Advanced Science, EarlyView.
Ruminant meat is widely appreciated for its distinctive flavor. Lipids play a central role in influencing meat flavor, yet their genetic and biochemical basis remains largely unexplored. Here, a comprehensive lipid genetic map of sheep muscle is constructed and 20 candidate genes potentially modulating lipid levels are identified to provide a roadmap ...
Xueying Zhang, Yuanyuan Kong, Jialei Chen, Ran Li, Zhongyu Wang, Yali Song, Tianshu Dai, Yuxin Fu, Beixiang Jiang, Jize Zeng, Shengwei Pei, Yangkai Liu, Qianjie Feng, Weiwei Fu, Zehu Yuan, Joram Mwashigadi Mwacharo, Fadi Li, Xiangpeng Yue   +17 more
wiley   +1 more source

Advancing Biomarker Research: In Situ Cu Isotope Analysis in Liver Tumors by LA-MC-ICP-MS. [PDF]

Anal Chem
Schannor M, Oelze M, Traub H, He Y, Schmidt R, Heidemann L, Savic LJ, Vogl J, Meermann B.   +8 more
europepmc   +1 more source