Results 251 to 260 of about 486,624 (356)

A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate

open access: yesAdvanced Science, EarlyView.
Here, a genetically encoded glutarate biosensor, Glusor, is developed based on transcriptional regulator CsiR. Glusor can quantify glutarate concentrations with good accuracy and precision. Then, the role of KgtP and YnfM are identified and characterized by using Glusor. Glusor also allows glutarate spatiotemporal resolution in live cells, facilitating
Kaiyu Gao   +12 more
wiley   +1 more source

Utilisation of Anthropogenic Food by Red Foxes (<i>Vulpes vulpes</i>) in Britain as Determined by Stable Isotope Analysis. [PDF]

open access: yesEcol Evol
Fletcher JWJ   +9 more
europepmc   +1 more source

Real‐Time Tracking of ASCT2‐Mediated Glutamine Uptake in Living Tumors With a Bioorthogonal Bioluminescent Probe

open access: yesAdvanced Science, EarlyView.
A bioluminescent probe, BLGLN, comprising BL568 and ASCT2‐uptaken AA201, enables real‐time monitoring and evaluation of ASCT2‐mediated glutamine uptake rates in living tumors via Staudinger ligation, aiding tumor metabolism studies and targeted therapeutics.
Bing‐Jun Zhou   +9 more
wiley   +1 more source

SIP‐SRS Imaging of Cell Wall Synthesis Identifies a Synergy between Micafungin and Amphotericin B

open access: yesAdvanced Science, EarlyView.
We employed glucose‐d7–based stable isotope probe‐assisted SRS microscopy (SIP‐SRS) C–D imaging to visualize fungal cell wall synthesis and remodeling under antifungal treatment. Amphotericin B (AmB) induced notable daughter cell wall thickening, prompting a combinational therapy with AmB and micafungin.
Meng Zhang   +6 more
wiley   +1 more source

Unveiling ancient Jerusalem's pastoral dynamics (7th to 2nd centuries BCE) with multi-isotope analysis. [PDF]

open access: yesSci Rep
Spiciarich A   +7 more
europepmc   +1 more source

Engineered Fusion Enzyme‐Mediated Non‐Consecutive Cyclization‐Glycosylation Enables Heterologous Synthesis of Antifungal Enfumafungin

open access: yesAdvanced Science, EarlyView.
The artificial biosynthetic pathway potentially involved in biosynthesis of enfumafungin is first reconstructed in an optimized Aspergillus oryzae chassis with the increased site‐specific integration efficiency and shortened time for marker recycling, which requires an artificial fusion enzyme EfuA(TC)FsoA(GT).
Yaohui Gao   +11 more
wiley   +1 more source

Correction: Osmium isotope analysis as an innovative tool for provenancing ancient iron: A systematic approach. [PDF]

open access: yesPLoS One
Brauns M   +5 more
europepmc   +1 more source

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