Results 141 to 150 of about 9,679,616 (302)

Isotope engineering achieved by local coordination design in Ti-Pd co-doped ZrCo-based alloys

Nature Communications
Deuterium/Tritium (D/T) handling in defined proportions are pivotal to maintain steady-state operation for fusion reactors. However, the hydrogen isotope effect in metal-hydrogen systems always disturbs precise D/T ratio control.
Jiacheng Qi, Xu Huang, Xuezhang Xiao, Xinyi Zhang, Panpan Zhou, Shuoqing Zhang, Ruhong Li, Huaqin Kou, Fei Jiang, Yong Yao, Jiangfeng Song, Xingwen Feng, Yan Shi, Wenhua Luo, Lixin Chen   +14 more
doaj   +1 more source

Isotope Effect in D₂O Negative Ion Formation in Electron Transfer Experiments: DO-D Bond Dissociation Energy. [PDF]

J Phys Chem Lett, 2023
Kumar S, Hoshino M, Kerkeni B, García G, Limão-Vieira P.   +4 more
europepmc   +1 more source

Isomeric Ag14 Nanoclusters With Distinct Photophysical and Nanomechanical Properties

Advanced Science, EarlyView.
Ligand‐shell isomerism in atomically precise Ag14 nanoclusters is demonstrated to regulate core distortion, photoluminescence, and mechanical properties. Subtle changes in phosphine ligand arrangement drive a pronounced emission shift from green to red and alter crystal rigidity, revealing a direct structure‐property correlation that offers new design ...
Vivek Yadav, Arijit Jana, Maya Khatun, Harshita Nagar, Sergei Lebedkin, Amit Mondal, Swetashree Acharya, Sami Malola, Sudhadevi Antharjanam, Moses Egor, Pijush Ghosh, Tomas Base, Manfred Kappes, Hannu Häkkinen, Thalappil Pradeep   +14 more
wiley   +1 more source

New Insights into the Volume Isotope Effect of Ice Ih from Polarizable Many-Body Potentials. [PDF]

J Phys Chem Lett, 2022
Rasti S, Jónsson EÖ, Jónsson H, Meyer J.   +3 more
europepmc   +1 more source

Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance

Advanced Science, EarlyView.
Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer, Ian de Ridder, Mahjoobeh Ehsani, Marasim Khan, Justin Kale, Lukas P. Frenzel, David Andrews, Spyridoula Karamanou, Ana J. Garcia‐Saez, Geert Bultynck   +9 more
wiley   +1 more source

Pseudogap Isotope Effect as a Probe of Bipolaron Mechanism in High Temperature Superconductors. [PDF]

Materials (Basel), 2021
Lakhno VD.
europepmc   +1 more source

A Second Pathogenic Protein, PolyGN2C‐iso2, Reveals a Dual‐Protein Pathology in Neuronal Intranuclear Inclusion Disease

Advanced Science, EarlyView.
This study reveals that NOTCH2NLC transcript variant 2 generates PolyGN2C‐iso2, an aggregating protein present within intranuclear inclusions of NIID patient tissues. A novel mouse model expressing PolyGN2C‐iso2 recapitulates white matter abnormalities and cognitive deficits, mechanistically linked to mitochondrial dysfunction. These findings support a
Kang Zhang, Wenhao Ma, Yi Zhou, Zhijie Wu, Pan Gao, Hongze Niu, Hongfei Tai, Tianyi Zhao, Zheyue Dong, Li Li, Yan Zhang, An Wang, Si Shen, Yueyang Li, Sifei Yu, Yan Peng, Wang Sheng, Xiaoyan Dong, Hua Pan, Kaibin Shi, Magdalena J. Koziol, Xiaobing Wu, Zaiqiang Zhang   +22 more
wiley   +1 more source

Metal-binding amino acid ligands commonly found in metalloproteins differentially fractionate copper isotopes

Scientific Reports
Copper (Cu) is a cofactor in numerous key proteins and, thus, an essential element for life. In biological systems, Cu isotope abundances shift with metabolic and homeostatic state. However, the mechanisms underpinning these isotopic shifts remain poorly
Corday R. Selden, Kathrin Schilling, Linda Godfrey, Nathan Yee   +3 more
doaj   +1 more source

Asymmetric Single‐Atom Catalysts Govern Diffusible and Non‐Diffusible Non‐Radical Pathways for Selective Degradation of Antibiotic Resistance Genes

Advanced Science, EarlyView.
Asymmetric single‐atom metal‐nitrogen‐carbon catalysts modulate the non‐radical pathway during peroxymonosulfate (PMS) activation. A fundamental contrast was revealed between diffusible singlet oxygen (1O2) and non‐diffusible electron‐transfer pathways (ETP) in antibiotic resistance gene (ARG) degradation.
Chen Gao, Jun Sun, Liang Zhang, Litao Lin, Zongfeng Wan, Bingcai Pan, Sheng Tang   +6 more
wiley   +1 more source

Selectivity in Enzymatic Phosphorus Recycling from Biopolymers: Isotope Effect, Reactivity Kinetics, and Molecular Docking with Fungal and Plant Phosphatases. [PDF]

Environ Sci Technol, 2022
Solhtalab M, Moller SR, Gu AZ, Jaisi D, Aristilde L.   +4 more
europepmc   +1 more source