Results 151 to 160 of about 12,068,996 (359)

Solvent isotope effects in the catalytic cycle of P450 CYP17A1: Computational modeling of the hydroxylation and lyase reactions. [PDF]

J Inorg Biochem, 2023
Denisov IG, Sligar SG.
europepmc   +1 more source

Isotope effects in the structural properties of solids [PDF]

, 1962
V.S. Kogan
openalex   +1 more source

Therapeutic Delivery of circDYM by Perillyl Alcohol Nanoemulsion Alleviates LPS‐Induced Depressive‐Like Behaviors

Advanced Science, EarlyView.
PANEs are specifically designed to enhance the brain delivery efficiency of circDYM compared to commercialized lipid nanoparticles (LNPs). Intranasal administration of PANE‐circDYM effectively alleviated LPS‐induced depressive‐like behaviors by mitigating neuroinflammation and promoting neuroplasticity.
Feng Gao, Zhongkun Zhang, Minzi Ju, Liang Bian, Huijuan Wang, Sibo Zhao, Ningbo Cai, Yu Wang, Yanpeng Jia, Ling Shen, Yuan Zhang, Honghong Yao   +11 more
wiley   +1 more source

Correlation of temperature dependence of hydride kinetic isotope effects with donor-acceptor distances in two solvents of different polarities. [PDF]

Org Biomol Chem, 2023
Bai M, Pratap R, Salarvand S, Lu Y.
europepmc   +1 more source

SECONDARY KINETIC ISOTOPE EFFECTS IN BIMOLECULAR NUCLEOPHILIC SUBSTITUTIONS: II. α-DEUTERIUM EFFECTS IN MENSCHUTKIN REACTIONS OF METHYL IODIDE [PDF]

, 1965
Kenneth T. Leffek, J. W. MacLean
openalex   +1 more source

Protease‐Mediated Synthesis of Zein Nanofibrils: From Structural Elucidation to Functional Application

Advanced Science, EarlyView.
The globular shape and hydrophobicity of zein made it unsuitable to be processed in pure aqueous environment. Pepsin‐mediated hydrolysis converts zein into water‐soluble and fibril‐forming peptides with a bioconversion rate exceeding 70%, enabling the self‐assembly of amyloid‐like nanofibrils.
Mingqin Li, Tonghui Jin, Simone Wüthrich, Jiangtao Zhou, Qiyao Sun, Ting Li, Zhou Dong, Eva Maria Zunzuneigui Bru, Raffaele Mezzenga   +8 more
wiley   +1 more source

Secondary isotope effects on pi-complex formation [PDF]

, 1964
E. A. Halevi, B. Ravid
openalex   +1 more source

TRIM25‐Mediated INSIG1 Ubiquitination Promotes MASH Progression Through Reprogramming Lipid Metabolism

Advanced Science, EarlyView.
TRIM25‐mediated ubiquitination of INSIG1 serves as a key driver of lipid metabolism dysregulation in MASH progression. It identifies a novel small‐molecule inhibitor, C27H26N2O4S, which effectively inhibits TRIM25 activity, reducing lipid accumulation and inflammation.
Hao Zhang, Xiangxu Kong, Wei Wang, Huaxin Zhou, Haoran Qu, Zhengyao Guan, Honglei Wu, Xiangyu Zhai, Bin Jin   +8 more
wiley   +1 more source

Role of isotopes in microturbulence from linear to saturated Ohmic confinement regimes

Physical Review Research
The first-principle gyrokinetic numerical experiments investigating the isotopic dependence of energy confinement achieve a quantitative agreement with experimental empirical scalings, particularly in Ohmic and L-mode tokamak plasmas.
Lei Qi, Jae-Min Kwon, T. S. Hahm, M. Leconte, Sumin Yi, Y. W. Cho, Janghoon Seo   +6 more
doaj   +1 more source

Isotope effects in dynamics of water isotopologues induced by core ionization at an x-ray free-electron laser. [PDF]

Struct Dyn, 2023
Guillemin R, Inhester L, Ilchen M, Mazza T, Boll R, Weber T, Eckart S, Grychtol P, Rennhack N, Marchenko T, Velasquez N, Travnikova O, Ismail I, Niskanen J, Kukk E, Trinter F, Gisselbrecht M, Feifel R, Sansone G, Rolles D, Martins M, Meyer M, Simon M, Santra R, Pfeifer T, Jahnke T, Piancastelli MN.   +26 more
europepmc   +1 more source