PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao +6 more
wiley +1 more source
Alpha heating, isotopic mass, and fast ion effects in deuterium–tritium experiments
R. Budny, JET Contributors
openalex +2 more sources
Isotope effects in fully deuterated hexoses, proteins and nucleic acids [PDF]
Joseph Katz +2 more
openalex +1 more source
Isotope effects on L-H threshold and confinement in tokamak plasmas
C. Maggi +26 more
semanticscholar +1 more source
Strong Proton‐Phonon Coupling Drives Fast Ion Transport in Perovskites
Experimental and computational phonon analysis of ABO3‐type proton conductor BaSnO3 shows that substitution on the B‐site with yttrium forms an imaginary phonon mode which is instrumental for the function as proton conductor. This overcompensates the adverse proton trapping effect of the yttrium.
Alexey Rulev +8 more
wiley +1 more source
Partial Hessian vibrational analysis: vapour pressure isotope effects\n and their relation with non-covalent interactions [PDF]
Luis Vásquez
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This study finds that the interaction between ABA‐OsCIPK2‐OsSWEET1A reduces the allocation of methane producing bacteria carbon source (acetic acid) content to the rhizosphere soil of ratoon season rice, thereby reducing methane emissions. Abstract Rice paddies are a major, persistent source of atmospheric methane (CH4), emission rates depend on the ...
Jingnan Zou +14 more
wiley +1 more source
Estimation of frequency factors for the calculation of kinetic isotope effects from classical and path integral free energy simulations. [PDF]
Giese TJ, York DM.
europepmc +1 more source
Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development
This study identifies three metabolic stages (E8.5, E9.5–10.5, E11.5–14.5) and two transition periods (E8.5–9.5, E10.5–11.5) in mouse placental development. NAD(H) emerges as a key dynamic metabolite that enhances embryonic growth through accelerated segmentation and increased proliferation of mouse embryonic stem cell (mESC)‐induced presomitic ...
Gang Chen +11 more
wiley +1 more source
Effects of abrupt changes in the Atlantic meridional overturning circulation over the Amazon Basin: an isotopic and elemental approach [PDF]
Stefano Crivellari
openalex +1 more source

