Results 201 to 210 of about 12,068,996 (359)

N‐loss isotope effects in the Peru oxygen minimum zone studied using a mesoscale eddy as a natural tracer experiment

, 2015
A. Bourbonnais, M. Altabet, C. Charoenpong, J. Larkum, H. Hu, H. Bange, L. Stramma   +6 more
semanticscholar   +1 more source

Transient Interdomain Interactions Modulate the Monomeric Structural Ensemble and Self‐Assembly of Huntingtin Exon 1

Advanced Science, EarlyView.
Polyglutamine (polyQ) tract expansion (≥ 36 amino acids) within the N‐terminal region of the Huntingtin protein (Httex1) causes Huntington's disease (HD), for which the underlying causes are not well‐understood. The authors performed computer simulations to understand the cause of HD at the molecular level.
Priyesh Mohanty, Tien Minh Phan, Jeetain Mittal   +2 more
wiley   +1 more source

HDAC6 and USP9X Control Glutamine Metabolism by Stabilizing GS to Promote Glioblastoma Tumorigenesis

Advanced Science, EarlyView.
Glioblastoma (GBM) growth relies on glutamine synthetase (GS), which is stabilized by histone deacetylase 6 (HDAC6) and deubiquitinated by ubiquitin‐specific peptidase 9, X‐linked (USP9X). HDAC6 promotes GS deacetylation, while USP9X removes its K48‐linked polyubiquitination, enhancing GS stability.
Go Woon Kim, Minhae Cha, Hien Thi My Ong, Jung Yoo, Yu Hyun Jeon, Sang Wu Lee, Soo Yeon Oh, Min‐Jung Kang, Youngsoo Kim, So Hee Kwon   +9 more
wiley   +1 more source

Apparent Kinetic Isotope Effects for Multi-Step Steady-State Reactions. [PDF]

J Phys Chem B
Williams IH.
europepmc   +1 more source

Isotope Effects on the Vaporization of Organic Compounds from an Aqueous Solution-Insight from Experiment and Computations. [PDF]

J Phys Chem B, 2021
Rostkowski M, Schürner HKV, Sowińska A, Vasquez L, Przydacz M, Elsner M, Dybala-Defratyka A.   +6 more
europepmc   +1 more source

Tritium-labeled compounds IX. Determination of isotope effects in reactions yielding water-t from nonvolatile reactants. Oxidation of aldoses-1-t with iodine

, 1963
Horace S. Isbell, Lorna T. Sniegoski
openalex   +1 more source

Hydrocyclization/Defluorination of CF3‐Substituted Acrylamides: Insights from Kinetics of Hydrogen Atom Transfer

Advanced Science, EarlyView.
The study develops a H•/H– transfer strategy enabling efficient hydrocyclization/defluorination of CF3‐acrylamides to synthesize Seletracetam derivatives with gem‐difluoroalkenes. Mechanistic studies reveal distinct pathways: the NiII‐H/PhSiH3 system operates through a hydrogen atom transfer process, while the 1,4‐Michael addition of H– appears to be ...
Yanjun Wan, Ronghui Shao, Jack R. Norton
wiley   +1 more source

Pre-steady-state kinetics and solvent isotope effects support the "billiard-type" transport mechanism in Na⁺ -translocating pyrophosphatase. [PDF]

Protein Sci, 2022
Malinen AM, Anashkin VA, Orlov VN, Bogachev AV, Lahti R, Baykov AA.   +5 more
europepmc   +1 more source

Session V: II. Investigations of isotope effects in organic systems (Part B) [PDF]

, 1964
V. J. Shiner, Brian M. Martin, Gerd Müllhofer   +2 more
openalex   +1 more source

Unveiling Surface Species Formed on Ni‐Fe Spinel Oxides During the Oxygen Evolution Reaction at the Atomic Scale

Advanced Science, EarlyView.
≈1 nm thick amorphous layer with a higher oxygen concentration is formed on the surfaces of pristine P‐doped NiFe2O4 and activated NiFe2O4. Such surface layer is thought to significantly promote the charge transfer kinetics compared to the oxyhydroxide layer grown on Ni1.5Fe1.5O4 during the oxygen evolution reaction. Abstract Optimizing electrocatalyst
Weikai Xiang, Sheila Hernandez, Pouya Hosseini, Fan Bai, Ulrich Hagemann, Markus Heidelmann, Tong Li   +6 more
wiley   +1 more source