Results 261 to 270 of about 12,174,017 (385)

Carbonate clumped isotope thermometry of deep-sea corals and implications for vital effects

, 2011
Nivedita Thiagarajan, Jess F. Adkins, John M. Eiler   +2 more
openalex   +1 more source

Dual‐Site Synergistic Mechanism via Single‐Atom and Vacancy Drives Lattice Oxygen Activation in Layered Double Hydroxides

Advanced Science, EarlyView.
A strategy utilizing high‐energy ion beam technology to engineer defects in layered double hydroxide (LDH) nanosheets enables the high loading of non‐noble metal Mo single atoms. The synergistic effect between oxygen vacancies and single atoms promotes a novel mechanism for lattice oxygen activation, thereby significantly enhancing the oxygen evolution
Shixin Wu, Wenyu Lu, Shijun Zhao, Kai Zhao, Ning Yan, Liqiu Huang, Derun Li, Tao Jiang, Hengyi Wu, Feng Ren   +9 more
wiley   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science, EarlyView.
A comprehensive technology platform enables high‐fidelity, volumetric MALDI imaging of 3D cell cultures by integrating custom embedding molds, a semi‐automated computational framework for 3D reconstruction, voxel‐instead of pixel‐based biomarker discovery, and immersive mixed reality data exploration.
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
wiley   +1 more source

Heavy water inhibits DNA double-strand break repairs and disturbs cellular transcription, presumably via quantum-level mechanisms of kinetic isotope effects on hydrolytic enzyme reactions. [PDF]

PLoS One
Yasuda T, Nakajima N, Ogi T, Yanaka T, Tanaka I, Gotoh T, Kagawa W, Sugasawa K, Tajima K.   +8 more
europepmc   +1 more source

Boron Nitride Nanomaterials Trigger Immunomodulatory Effects in Human Broncho‐Epithelial Cells by Modulating Eicosanoid Lipid Signaling

Advanced Science, EarlyView.
This study demonstrates that BNNT exposure disrupts lipid homeostasis in bronchial epithelial cell cultures and activates eicosanoid lipid biosynthesis, producing inflammatory lipid mediators like leukotrienes. These effects are more pronounced in asthmatic cell cultures compared to healthy ones.
Govind Gupta, Jonas Bossart, Sènan Mickael D'Almeida, Luis Augusto Visani de Luna, Christoph Schwärzler, Tingting Fu, Vanesa Ayala‐Nunez, Alexander Gogos, Marija Buljan, Vera M Kissling, Emmanuel Flahaut, Miguel Garcia, Cyrill Bussy, Peter Wick, Tina Buerki‐Thurnherr   +14 more
wiley   +1 more source

Insights into the Mechanism of O(³P)-Mediated Oxidation of Alkenes through Kinetic Isotope Effects and Computational Modeling. [PDF]

J Org Chem
Maness PF, McCulla RD.
europepmc   +1 more source

Deuteration Induced Electron‐Phonon Coupling Modulation: Suppressing Energy Dissipation and Enhancing Carrier Separation in Organic Photocatalysis

Advanced Science, EarlyView.
During charge transport, photogenerated carriers exchange energy with lattice vibrations, influencing photocatalytic performance. The deuteration strategy enhances exciton dissociation and suppresses non‐radiative energy loss, significantly improving photocatalytic hydrogen evolution.
Hongli Sun, Zirui Zhou, Yunfei Ma, Qingzhu Xu, Yanglong Liao, Cheng Han, Yue Zheng, Xiaosong Cao, Yu Wang, Zutao Fan, Jianfeng Zhao, Chenliang Su, Fengtao Fan, Bin Liu   +13 more
wiley   +1 more source

Study of the Effects of Remote Heavy Group Vibrations on the Temperature Dependence of Hydride Kinetic Isotope Effects of the NADH/NAD⁺ Model Reactions. [PDF]

ACS Omega
Singh G, Austin A, Bai M, Bradshaw J, Hammann BA, Kabotso DEK, Lu Y.   +6 more
europepmc   +1 more source

Alternative Pathway for Methyl Supply through the Coupling of SHMT1 and PEMT to Maintain Astrocytic Homeostasis in Parkinson's Disease

Advanced Science, EarlyView.
In Parkinson's disease, SHMT1 downregulation disrupts its interaction with PEMT in astrocytes, reducing SAM levels. This leads to H3K4me1 hypomethylation and decreased Slc1a2/Glul expression, ultimately exacerbating neuroexcitotoxicity and dopaminergic neuron loss.
Yue‐Han Chen, Rong‐Xin Zhu, Nuo‐Xi Zhang, Ting‐Ting Sun, Xi‐Wei Zhang, Yu‐Jie Zhao, Ben‐Yu He, Hang Yao, Ren‐Hong Du, Lei Cao, Wen‐Bin Zhang, Wei‐Guo Liu, Yun Cai, Cong Wang, Gang Hu, Yao Wei, Yang Liu, Ming Lu   +17 more
wiley   +1 more source

Ligand effects, solvent cooperation, and large kinetic solvent deuterium isotope effects in gold(I)-catalyzed intramolecular alkene hydroamination. [PDF]

Beilstein J Org Chem
Lan R, Yager B, Jee Y, Day CS, Jones AC.
europepmc   +1 more source