Results 171 to 180 of about 1,839,261 (340)

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

open access: yesAdvanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu   +9 more
wiley   +1 more source

Acidosis Forces Fatty Acid Uptake and Metabolism in Cancer Cells Regardless of Genotype

open access: yesAdvanced Science, EarlyView.
This study demonstrates that biological acidosis, commonly observed in tumors and ischemic conditions, actively promotes the protonation of fatty acids, thereby facilitating the uptake of their neutral forms. Consequently, the preference for lipid metabolism in acid‐exposed cells does not arise from genetic reprogramming that prioritizes lipids as the ...
Sébastien Ibanez   +20 more
wiley   +1 more source

Uncovering the CO2 Capture Mechanism of NaNO3-Promoted MgO by 18O Isotope Labeling. [PDF]

open access: yesJACS Au, 2022
Landuyt A   +6 more
europepmc   +1 more source

Multiplexed proteome analysis with neutron-encoded stable isotope labeling in cells and mice

open access: yesNature Protocols, 2018
K. Overmyer   +5 more
semanticscholar   +1 more source

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